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Oxcarbazepine

About Oxcarbazepine

Oxcarbazepine belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy/seizures/fits. Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain, leading to seizures, unusual behaviour, and loss of awareness. 

Oxcarbazepine works by reducing the attacks of seizures or epilepsy by decreasing the nerve impulses that cause fits. Thereby helps in controlling seizures.

You are advised to take Oxcarbazepine as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, double vision, stomach pain, diarrhoea or constipation, and weakness. You are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Oxcarbazepine without consulting your doctor to avoid precipitating seizures. Do not take Oxcarbazepine if you are pregnant or planning for pregnancy unless prescribed by the doctor. Avoid taking Oxcarbazepine while breastfeeding as it may cause side effects in breastfed babies. Oxcarbazepine should not be given to children unless prescribed. Consult your doctor immediately if you experience suicidal tendencies.

Uses of Oxcarbazepine

Treatment of Epilepsy

Medicinal Benefits

Oxcarbazepine belongs to a group of medicines called anti-convulsants or anti-epileptics. Oxcarbazepine is used to treat epilepsy/seizures/fits. Oxcarbazepine works by decreasing the nerve impulses that cause fits and pain, thereby controlling seizures. Oxcarbazepine is used alone or in combination to treat and prevent partial seizures in adults. Oxcarbazepine may be used as sole therapy in treating and preventing seizures in children above 4 years or is used in combination in children above 2 years. Oxcarbazepine does not cause dependence or tolerance.

Directions for Use

Swallow it as a whole with a glass of water; do not chew or crush the dosage form. Dispersible tablet: Disperse the tablet in a tablespoon full of boiled and cooled water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oxcarbazepine

  • Dizziness
  • Sleepiness
  • Tiredness
  • Headache
  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Constipation
  • Weakness

Drug Warnings

Do not take Oxcarbazepine if you are allergic to any of its contents. Inform your doctor if you have or had heart problems, kidney and liver problems, if you have low levels of sodium in blood or if you are taking medicines that could lower the levels of sodium in the blood, or if you are using hormonal contraceptives. Do not stop taking Oxcarbazepine without consulting your doctor to avoid precipitating seizures. Consult your doctor if you are pregnant or planning for pregnancy. Nursing mothers should consult the doctor before using Oxcarbazepine as it may pass into the breast milk and affect the baby. Oxcarbazepine should not be given to children unless prescribed. Avoid consuming alcohol along with Oxcarbazepine as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Drug Interactions

Drug-Drug Interactions: Oxcarbazepine may have interaction with antipsychotic (aripiprazole, lurasidone, quetiapine), sedative (zolpidem), anti-depressant (duloxetine, escitalopram, pregabalin, fluoxetine, trazodone, sertraline), antibiotics (erythromycin), pain killer (hydrocodone, methadone), anti-convulsant (lamotrigine, topiramate), antacid (esomeprazole), anti-anxiety (alprazolam), an antihistamine (cetirizine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have depression, liver disease, kidney dysfunction, suicidal tendency, irregular heartbeat, thyroid dysfunction, hyponatremia (low levels of sodium in the blood), or blood disorders.

Drug-Drug Interactions Checker List:

  • ARIPIPRAZOLE
  • QUETIAPINE
  • LURASIDONE
  • ZOLPIDEM
  • DULOXETINE
  • ESCITALOPRAM
  • PREGABALIN
  • FLUOXETINE
  • TRAZODONE
  • SERTRALINE
  • ERYTHROMYCIN
  • HYDROCODONE
  • METHADONE
  • LAMOTRIGINE
  • TOPIRAMATE
  • ESOMEPRAZOLE
  • ALPRAZOLAM
  • CETIRIZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking Oxcarbazepine as it may increase dizziness and sleepiness.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Oxcarbazepine should not be taken by breastfeeding mothers as it passes into breast milk and could lead to side-effects in breastfed babies.

    • Safety Warning

      Driving

      unsafe

      Avoid driving as Oxcarbazepine may cause drowsiness, sleepiness and tiredness.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      safe if prescribed

      Oxcarbazepine can be given to children aged above 6years if prescribed by the doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.

    • Atkins's diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

    • Exercising regularly helps in maintaining weight and improving overall health. 

    • Rest well, and get plenty of sleep.

    • Avoid smoking and alcohol consumption.

    • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

    • Have a seizure response plan, this helps those around you know what to do.

    • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

    • Understand what triggers seizures and try reducing or avoiding them.

    • Please pay attention to overall health as it can help in reducing seizure activity.

    • Install an alarm or emergency device to get assistance during a seizure attack.

    Patients Concern

    Disease/Condition Glossary

    Epilepsy/Seizures: Seizures, also known as fits or convulsions, are a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

    FAQs

    Oxcarbazepine is used to treat epilepsy/seizures/fits.

    Oxcarbazepine works by decreasing the nerve impulses that cause fits (seizures episodes) in the brain. Thereby helps in controlling seizures.

    Oxcarbazepine causes dizziness, sleepiness and tiredness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or sleepy.

    Do not discontinue Oxcarbazepine without consulting your doctor. To treat your condition effectually, continue taking Oxcarbazepine for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Oxcarbazepine; your doctor will reduce the dose gradually to avoid precipitating seizures.

    Oxcarbazepine may cause weight gain, so try to maintain a healthy weight (BMI between 18.5-24.9) by following a healthy diet and exercising regularly.

    Oxcarbazepine may cause agitation or mood changes. Talk to your doctor if you experience any changes in mood, behaviour, or emotions while taking Oxcarbazepine.

    Oxcarbazepine may cause low sodium levels in the blood. This could lead to confusion, reduced concentration, vision problems, nausea, vomiting or worsening of seizures. Regular monitoring of sodium levels is advised while taking Oxcarbazepine.

    Oxcarbazepine may cause sleepiness or dizziness as side effect. Therefore, unless you are familiar with the effects of Oxcarbazepine on you, be cautious while driving or doing any physical activity that requires mental focus.

    No, Oxcarbazepine is not a steroid. It is anticonvulsant drug used to treat epilepsy.

    Oxcarbazepine has less side effects as compared to carbamazepine. Furthermore, Oxcarbazepine can be started with a clinically effective dose whereas carbamazepine may require frequent doctor visits before an effective dose can be decided based on the patient’s response to the treatment.

    You should pay attention to any changes, especially sudden changes in behaviour, mood, feelings or thoughts. Be aware of common warning signs that might be an indication for risk of suicide. Some of these include thinking or talking about hurting yourself or ending your life, withdrawing from family and friends, becoming depressed or worsening your depression. Make sure you don’t skip your scheduled visit with your doctor. Maintain contact with the doctor in between appointments.

    Take Oxcarbazepine as advised by your doctor. It can be taken either with or without food. Take it at the same time every day for effective results.

    There have been no reports of Oxcarbazepine affecting fertility in either males or females. However, if you have any concerns, please discuss with your doctor.

    Yes, Oxcarbazepine may cause hair loss as a side effect. It is not necessary for everyone taking Oxcarbazepine to experience this side effect. However, if you have severe hair loss, please consult your doctor.

    Oxcarbazepine should be avoided if you are allergic to oxcarbazepine, eslicarbazepine or to any of its ingredients. Also, pregnant women and those who use birth control medicine should avoid Oxcarbazepine unless advised by the doctor.

    You are recommended to consult your doctor before taking Oxcarbazepine with other medicines to avoid drug interactions.

    If you have kidney or liver problems, or have or have had suicidal thoughts or actions, mood problems or depression, inform your doctor before taking Oxcarbazepine.

    Oxcarbazepine may cause side effects such as headache, dizziness, nausea, vision problems, sleepiness, tiredness, vomiting and tremors. If these side effects persist or worsen, please consult your doctor.

    Available Medicines for

    Oxcarbazepine

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