Omeprazole+ondansetron
About Omeprazole+ondansetron
Omeprazole+ondansetron is used in the treatment of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is forcible voluntary or involuntary emptying of stomach contents through the mouth.
Omeprazole+ondansetron is a combination of two drugs, namely Omeprazole (proton pump inhibitor) and Ondansetron (anti-emetic). Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Take Omeprazole+ondansetron as prescribed. Your doctor will advise you on how often you should take it based on your medical condition. Omeprazole+ondansetron may cause common side effects such as headache, a feeling of warmth, constipation, diarrhoea, or flatulence (wind). Most of these side effects of Omeprazole+ondansetron do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Omeprazole+ondansetron. If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Omeprazole+ondansetron.
Uses of Omeprazole+ondansetron
Medicinal Benefits
Omeprazole+ondansetron belongs to a group of medicines called gastrointestinal agents that prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness. It may also be indicated in conditions such as gastroesophageal reflux disease (GERD) and ulcers in the stomach or intestine. It contains Omeprazole and Ondansetron. Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Directions for Use
Storage
Side Effects of Omeprazole+ondansetron
- Headache
- A feeling of warmth
- Constipation
- Diarrhoea
- Flatulence (wind)
Drug Warnings
If you are allergic to omeprazole, ondansetron, granisetron, dolasetron, pantoprazole, lansoprazole, rabeprazole, esomeprazole or other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor. Drive only if you are alert after taking Omeprazole+ondansetron. If you are taking nelfinavir (for HIV infection) or apomorphine (for Parkinson’s disease), do not take Omeprazole+ondansetron. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Omeprazole+ondansetron. Omeprazole in Omeprazole+ondansetron may alter the results of some tests related to cancer. Therefore, tell your doctor, nurse or hospital staff you are taking Omeprazole+ondansetron. Your doctor may advise you to stop taking this medicine for at least five days if you undergo certain tests.
Drug Interactions
Drug-Drug Interaction: If you are taking an antiparkinson drug (apomorphine) or any medicine containing nelfinavir (for HIV infection) or any other prescription or non-prescription medicines or supplements, inform your doctor.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: If you have problems with the levels of salts (potassium, sodium, and magnesium) in your blood, a blockage in your gut, severe constipation, or liver or heart problems, inform your doctor.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIf you have any concerns regarding alcohol consumption while taking Omeprazole+ondansetron, please discuss them with your doctor.
Pregnancy
consult your doctorIf you are pregnant or planning pregnancy, please inform your doctor before taking Omeprazole+ondansetron.
Breast Feeding
consult your doctorIf you are a breastfeeding mother, please inform your doctor before taking Omeprazole+ondansetron.
Driving
cautionOmeprazole+ondansetron usually does not affect your ability to drive or operate machinery. However, if you experience visual disturbances or dizziness after taking Omeprazole+ondansetron, avoid driving or operating machinery.
Liver
cautionIf you have severe liver problems, inform your doctor, as a lower dose is recommended in such cases.
Kidney
consult your doctorIf you have kidney problems, please inform your doctor before taking Omeprazole+ondansetron.
Children
cautionOmeprazole+ondansetron should be used in dose and duration as advised by a doctor only. However, if you have any concerns regarding using Omeprazole+ondansetron for children below 1 year, please consult a doctor.
Habit Forming
Diet & Lifestyle Advise
- Eat a healthy, low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating overly sweet food and include more salty food, especially if you have been vomiting.
- Also, if you like to vomit at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off.
- Drink any other liquid at least 30 minutes after eating food.
- If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.
Patients Concern
Disease/Condition Glossary
Nausea and vomiting: Nausea is an uneasy feeling in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. It can be triggered by taste, anxiety, smell, pain, or irritation of the stomach. Usually, a person experiences nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients during everyday activities. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration.
FAQs
Omeprazole+ondansetron is used to treat Nausea and Vomiting.
Omeprazole+ondansetron contains Omeprazole and Ondansetron. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Ondansetron blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Omeprazole+ondansetron may cause constipation as a side effect. It is not necessary for everyone taking Omeprazole+ondansetron to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Omeprazole+ondansetron should be used with caution in patients suffering from liver problems. Inform your doctor if you have any liver problems before taking Omeprazole+ondansetron so that the dose may be adjusted appropriately.
