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Ofloxacin+metronidazole+simethicone

About Ofloxacin+metronidazole+simethicone

Ofloxacin+metronidazole+simethicone is an antidiarrheal medicine used to treat diarrhea in children. Diarrhea is defined as loose, watery and frequent bowel movements. This can be acute (temporary) or chronic (long-lasting). Most times, diarrhoea can occur due to various types of bacteria.

Ofloxacin+metronidazole+simethicone is a combination medicine containing Ofloxacin (quinolone antibiotic), Metronidazole (antimicrobials), and Simethicone (digestive enzyme). Ofloxacin inhibits bacterial DNA replication by attaching to an enzyme known as DNA gyrase. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It inhibits the protein synthesis interacting with DNA. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping).

Ofloxacin+metronidazole+simethicone may cause certain side effects, such as vomiting, diarrhea, nausea, bloating, headache, and stomach pain. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist or bother your child, please consult your pediatrician. Ofloxacin+metronidazole+simethicone should be given as advised by your child's doctor. Do not give your child more than the prescribed dose of Ofloxacin+metronidazole+simethicone. Ofloxacin+metronidazole+simethicone can be given with or without food. The dose of the medicine will be decided by your pediatrician, depending upon the severity of the infection.

Ofloxacin+metronidazole+simethicone is intended for pediatric use only. Avoid giving Ofloxacin+metronidazole+simethicone to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition and ongoing medications, including OTC drugs and vitamin supplements, to rule out any possible side effects/interactions. Let your child's doctor know if your child has lung disease, muscle weakness, liver and kidney disease before giving Ofloxacin+metronidazole+simethicone to the child.

Uses of Ofloxacin+metronidazole+simethicone

Treatment of Diarrhoea

Medicinal Benefits

Ofloxacin+metronidazole+simethicone contains Ofloxacin (quinolone antibiotic), Metronidazole (antimicrobials), and Simethicone (digestive enzyme). Ofloxacin inhibits bacterial DNA replication by attaching to an enzyme known as DNA gyrase. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It inhibits the protein synthesis interacting with DNA. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping). Thus Ofloxacin+metronidazole+simethicone helps treat diarrhoea and reduce symptoms of flatulence and stomach discomfort.

Directions for Use

Shake the container well before each use. Measure the required amount of this medicine into the measuring cup and administer it to your child. It is advised to measure the quantity accurately with the help of a syringe or measuring spoon containing markings.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofloxacin+metronidazole+simethicone

  • Nausea
  • Diarrhea
  • Stomach upset
  • Bloating
  • Vomiting

Drug Warnings

Avoid giving Ofloxacin+metronidazole+simethicone to your child if she/he is allergic to antibiotics. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, let your paediatrician know if your child has lung disease, muscle weakness, liver, and kidney disease. Dairy products should be avoided along with Ofloxacin+metronidazole+simethicone. Inform your paediatrician if your child is taking any iron or zinc supplements or antacids. Do not stop giving this medicine even if your child feels better. Complete the full course as prescribed.

Drug Interactions

Drug-Drug Interactions: Ofloxacin+metronidazole+simethicone may interact with caffeine-containing medications, antacids, etc. Give Ofloxacin+metronidazole+simethicone either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc.

Drug-Food Interactions: No interactions found/established. 

Drug-Disease Interactions: Inform your doctor before administering Ofloxacin+metronidazole+simethicone if your child has any history of lung disease or kidney or liver disease.

Drug-Drug Interactions Checker List:

  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • CALCIUM CARBONATE
  • Safety Advice

    • Safety Warning

      Alcohol

      not applicable

      -

    • Safety Warning

      Pregnancy

      not applicable

      -

    • Safety Warning

      Breast Feeding

      not applicable

      -

    • Safety Warning

      Driving

      not applicable

      -

    • Safety Warning

      Liver

      caution

      If your child has a liver impairment, inform your doctor before giving Ofloxacin+metronidazole+simethicone.

    • Safety Warning

      Kidney

      caution

      If your child has kidney impairment, inform your doctor before giving Ofloxacin+metronidazole+simethicone.

    • Safety Warning

      Children

      safe if prescribed

      Ofloxacin+metronidazole+simethicone is safe for children if prescribed by the doctor. Based on your child's condition, the doctor will suggest a suitable dose. Do not give your child more than the prescribed dose.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more fiber-enriched food in your child’s diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth.
    • Fiber foods may help restore healthy gut bacteria after a course of antibiotics.
    • Avoid giving too much calcium, or iron-enriched foods, as it might affect the working of Ofloxacin+metronidazole+simethicone. 
    • Make your child drink more fluids to avoid dehydration.
    • Do not make your child drink or eat a lot of caffeine-containing products such as cola or chocolate. Ofloxacin+metronidazole+simethicone may increase nervousness, sleeplessness, and anxiety.

    Patients Concern

    Disease/Condition Glossary

    Diarrhoea: Diarrhoea is defined as the occurrence of loose and watery stools due to frequent bowel movements in the stomach. This can be acute (temporary- lasts for a few days) or chronic (long-lasting- lasts for a few weeks). Diarrhoea can lead to the loss of water along with salts, electrolytes, and minerals from the body. This can occur due to various reasons such as food intolerance, food allergy, adverse reaction to a medication, or infections caused by microorganisms. Symptoms include nausea, abdominal pain, cramps, bloating, dehydration, watery loose stools, and frequent urge to evacuate the bowels.

    FAQs

    Ofloxacin+metronidazole+simethicone is used to treat Diarrhoea.

    Ofloxacin+metronidazole+simethicone contains Ofloxacin (quinolone antibiotic), Metronidazole (antimicrobials), and Simethicone (digestive enzyme). Ofloxacin inhibits bacterial DNA replication by attaching to an enzyme known as DNA gyrase. Metronidazole kills parasites and anaerobic bacteria that are responsible for causing infections. It inhibits the protein synthesis interacting with DNA. Simethicone works by decreasing the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping).

    No. It is always advised to complete the entire treatment course as prescribed. If the treatment is stopped abruptly, it may lead to drug resistance.

    Available Medicines for

    Ofloxacin+metronidazole+simethicone

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