Quinapril+hydrochlorothiazide
About Quinapril+hydrochlorothiazide
Hydrochlorothiazide+quinapril is indicated in treating high blood pressure (hypertension). It lowers blood pressure and reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. High blood pressure is when the blood exerts increased pressure on the walls of blood vessels.
Hydrochlorothiazide+quinapril contains Quinapril and Hydrochlorothiazide. Quinapril widens the blood vessels in the body and helps reduce their pressure. Hydrochlorothiazide helps the body get rid of extra fluid. Together, Hydrochlorothiazide+quinapril helps treat high blood pressure.
In some cases, Hydrochlorothiazide+quinapril may cause side effects such as diarrhoea, dizziness, headache, tiredness, and indigestion. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.
Do not take Hydrochlorothiazide+quinapril if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Hydrochlorothiazide+quinapril may cause dizziness, so drive only if you are alert. Keep the doctor informed about your health condition and medications to avoid unpleasant side effects/interactions.
Uses of Quinapril+hydrochlorothiazide
Medicinal Benefits
Hydrochlorothiazide+quinapril is used to treat high blood pressure (hypertension). It is a combination of two anti-hypertensive medicines, Quinapril and Hydrochlorothiazide. Quinapril is an angiotensin-converting enzyme (ACE) inhibitor) which reduces the pressure in the vessels by widening the blood vessels in the body. Hydrochlorothiazide is a diuretic that helps the body to get rid of extra fluid. Together, Hydrochlorothiazide+quinapril helps treat high blood pressure.
Directions for Use
Storage
Side Effects of Quinapril+hydrochlorothiazide
- Diarrhoea
- Indigestion
- Dizziness
- Headache
- Tiredness
- Feeling or being sick
- Mild stomach pain
Drug Warnings
Do not take Hydrochlorothiazide+quinapril if you are allergic to any of its components, if you have a history of angioedema, kidney disease or problems passing urine, obstruction in the heart that slows blood in the heart, hereditary (inherited)/idiopathic (unknown cause) angioneurotic oedema (swelling of the face, tongue or throat which causes difficulty breathing), diabetes or impaired kidney function and you are treated with a blood pressure lowering medicine containing aliskiren, or if you are taking sacubitril/valsartan, a medicine for heart failure. Inform the doctor if you have/had skin cancer, aortic stenosis (narrowing of the main blood vessel from the heart), kidney, liver or heart problems, low blood pressure, dry cough, collagen vascular disease (deposits of collagen in your blood vessels), asthma, angioedema, diabetes, gout, systemic lupus erythematosus (SLE, an allergic condition which causes skin rashes, joint pain and fever), salt/electrolyte imbalance, eye problems, pregnant or breastfeeding, or if you are due to undergo any surgery, or desensitisation treatment. Seek medical attention if you experience symptoms of visual disturbances/increased pressure in the eye (intense pain, headaches, redness of the eye, tender eye area, misty vision and loss of vision), neutropenia or agranulocytosis (fever, mouth ulcers, sore throat, unexplained bruising or bleeding, tiredness, or a blood problem such as low/lack of white blood cells), breathing or lung problems (severe shortness of breath or difficulty breathing).
Drug Interactions
Drug-Drug Interactions: Inform the doctor if you are taking medicines used to treat high blood pressure (aliskiren), medicines used to treat heart failure (sacubitril/valsartan), cholesterol-lowering medicines (cholestyramine, colestipol), neurotransmitters (norepinephrine epinephrine), antibiotics (sulfamethoxazole, trimethoprim), anaesthetics, anti-manic agents (lithium), painkillers (aspirin, ibuprofen), corticosteroids, antacids, antidiarrheals (racecadotril) or anti-diabetics (vildagliptin).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform the doctor if you have diabetes, impaired kidney function, heart problems, or angioneurotic oedema (swelling of the face, tongue or throat which causes difficulty breathing).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIt is not known if alcohol affects Hydrochlorothiazide+quinapril. Please consult the doctor.
Pregnancy
cautionConsult the doctor if you are pregnant, think you may be pregnant or planning for pregnancy. Hydrochlorothiazide+quinapril is not recommended during pregnancy and must not be taken when more than three months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Breast Feeding
unsafeHydrochlorothiazide+quinapril is not recommended for mothers who are breastfeeding.
Driving
cautionHydrochlorothiazide+quinapril may cause dizziness in some cases. Drive or operate heavy machinery only if you are alert.
Liver
consult your doctorPlease consult the doctor if you have liver problems or any concerns regarding this.
Kidney
cautionHydrochlorothiazide+quinapril may not be recommended if you have impaired kidney function. Please consult the doctor if you have kidney problems or any concerns regarding this.
Children
unsafeHydrochlorothiazide+quinapril is recommended for children below 18 years.
Habit Forming
Diet & Lifestyle Advise
- Follow a low-salt and low-fat diet.
- Exercise regularly for at least 30 minutes most days.
- Eat a diet rich in whole grains, vegetables, and fruits.
- Avoid smoking and alcohol consumption.
- Maintain a healthy weight with proper diet and exercise.
- Manage stress with meditation, yoga, and massage.
Special Advise
- Your doctor may advise regular monitoring of kidney function, blood pressure and the amount of electrolytes in your blood at regular intervals.
- Hydrochlorothiazide+quinapril may affect the results of some laboratory tests. If you are due to undergo any tests, inform the doctor that you are taking Hydrochlorothiazide+quinapril.
- Do not start taking Hydrochlorothiazide+quinapril if you are pregnant or planning to become pregnant. Talk to the doctor if you have any concerns.
Patients Concern
Disease/Condition Glossary
High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels, leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, there are no signs or symptoms of hypertension.
FAQs
Hydrochlorothiazide+quinapril is used to treat hypertension (high blood pressure).
Hydrochlorothiazide+quinapril widens the blood vessels and facilitates the removal of extra fluid from the body, helping treat high blood pressure.
High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Hydrochlorothiazide+quinapril are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.
Please do not stop taking Hydrochlorothiazide+quinapril without consulting your doctor, as it may raise your blood pressure. To treat your condition effectively, continue taking Hydrochlorothiazide+quinapril for as long as your doctor has prescribed it. Do not hesitate to speak with your doctor if you experience difficulty taking Hydrochlorothiazide+quinapril.
Treatment with hydrochlorothiazide, especially on long-term use with high doses, might increase the risk of skin and lip cancer (non-melanoma skin cancer). Therefore, protect your skin from sun exposure and UV rays while taking Hydrochlorothiazide+quinapril. Consult the doctor if you have had skin cancer or if you develop an unexpected skin lesion during the treatment.