Nebivolol+hydrochlorothiazide
About Nebivolol+hydrochlorothiazide
Hydrochlorothiazide+nebivolol is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. Hydrochlorothiazide+nebivolol is a combination medication generally used when a single medicine cannot control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.
Hydrochlorothiazide+nebivolol contains nebivolol and hydrochlorothiazide. Nebivolol is a beta blocker that works on the heart, particularly to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time.
You may experience nausea, constipation, diarrhoea, fatigue, headache, dizziness, decreased potassium level in the blood, increased blood uric acid, altered blood lipid level, breathlessness, swelling of hands & feet, paresthesia (burning sensation of the skin), decreased magnesium level in the blood, increased calcium level in blood. Most of these side effects of Hydrochlorothiazide+nebivolol do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Do not take Hydrochlorothiazide+nebivolol if you are allergic to any of its components. Before taking Hydrochlorothiazide+nebivolol, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. It is recommended not to take Hydrochlorothiazide+nebivolol if you are pregnant or breastfeeding.
Uses of Nebivolol+hydrochlorothiazide
Medicinal Benefits
Hydrochlorothiazide+nebivolol is a combination of Nebivolol (beta-blockers/ blood pressure-lowering medicines) and Hydrochlorothiazide (thiazide diuretic or water pill). Nebivolol is a beta blocker that works on the heart specifically to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time. Thus Hydrochlorothiazide+nebivolol lowers blood pressure and prevents the risk of stroke, heart attack and oedema (fluid overload).
Directions for Use
Storage
Side Effects of Nebivolol+hydrochlorothiazide
- Nausea
- Constipation
- Diarrhoea
- Fatigue
- Headache
- Dizziness
- Decreased potassium level in the blood
- Increased blood uric acid
- Altered blood lipid level
- Breathlessness
- Swelling of hands & feet
- Paresthesia (burning sensation of the skin)
- Decreased magnesium level in the blood
- Increased calcium level in the blood
Drug Warnings
Before using Hydrochlorothiazide+nebivolol, inform your doctor if you have liver disease, kidney disease, eye problem (glaucoma), asthma, increased uric acid level (gout), diabetes, hyperlipidemia (increased level of lipid) or hyperthyroidism (increased level of thyroid). Hydrochlorothiazide+nebivolol should not be given to people allergic to Hydrochlorothiazide+nebivolol, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. It is contraindicated in low blood pressure (hypotension) and aortic stenosis (heart valve problem). Hydrochlorothiazide+nebivolol can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Hydrochlorothiazide+nebivolol and breastfeeding.
Drug Interactions
Drug-Drug Interactions: Hydrochlorothiazide+nebivolol may interact with other diuretics, blood pressure-lowering drugs (amiodarone, amlodipine, clonidine, digoxin, diltiazem, disopyramide), mental illness medications (amisulpiride, chlorpromazine, haloperidol), depression medications (amitriptyline, fluoxetine, paroxetine), antispasmodic medication (baclofen), anti-cancer medications (cyclophosphamide, fluorouracil, methotrexate), mood stabilizer (lithium), angina medication (bepridil), blood sugar-lowering medicines (insulin and oral antidiabetic drugs, metformin), medicines for gout (allopurinol, probenecid, sulfinpyrazone), drugs used to treat low blood pressure or slow heart rate (noradrenaline). If you are taking any of the above, speak with your doctor.
Drug-Food Interactions: You are recommended not to consume alcohol with a Hydrochlorothiazide+nebivolol to avoid unpleasant side effects.
Drug-Disease Interactions: Hydrochlorothiazide+nebivolol may interact with disease conditions, including liver function impairment, Anuria (severe renal insufficiency), cardiovascular diseases, Hypotension, bronchospasm (bronchial asthma), abnormal levels of potassium, calcium, sodium and symptomatic hyperuricemia (excess of uric acid in the blood).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol and Hydrochlorothiazide+nebivolol to avoid unpleasant side effects like drowsiness and dizziness.
Pregnancy
unsafeHydrochlorothiazide+nebivolol is not recommended during pregnancy. Hydrochlorothiazide+nebivolol contains hydrochlorothiazide that crosses the placenta. This may cause fetal damage and can affect the unborn baby (fetus).
Breast Feeding
unsafeTell your doctor if you are breast-feeding or about to start breast-feeding. Hydrochlorothiazide+nebivolol is not recommended for mothers who are breast-feeding.
Driving
cautionHydrochlorothiazide+nebivolol usually causes drowsiness and dizziness, affecting your ability to drive or operate machinery.
Liver
cautionHydrochlorothiazide+nebivolol to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.
Kidney
cautionHydrochlorothiazide+nebivolol to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.
Children
cautionLimited information is available regarding the usage of Hydrochlorothiazide+nebivolol in children, so please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
- Keep your weight under control with a BMI of 19.5-24.9.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Be mindful of salt; consume no more than 2,300 mg each day.
- Limit or avoid alcohol consumption.
- Quitting smoking is the best strategy to lower the risk of heart disease.
Special Advise
Your doctor may advice regular blood sugar monitoring as Hydrochlorothiazide+nebivolol may cause changes in your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Hypertension: The blood exerts increased pressure on the walls of blood vessels, leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, there are no signs or symptoms of hypertension.
FAQs
Hydrochlorothiazide+nebivolol is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.
Hydrochlorothiazide+nebivolol contains nebivolol and hydrochlorothiazide. Nebivolol is a beta blocker that works on the heart to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time.
Hydrochlorothiazide+nebivolol can be safely taken as long as your doctor has prescribed it. Conditions such as high blood pressure are life-long, and one should not abruptly discontinue them without discussing them with a doctor.
If you have missed a dose of Hydrochlorothiazide+nebivolol, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place. If it is time for you to take your next dose, do not take both doses together. Take only one dose; taking a double dose of Hydrochlorothiazide+nebivolol will lead to low blood pressure.
Yes, Hydrochlorothiazide+nebivolol can cause dizziness. Avoid driving or operating any heavy machinery while taking Hydrochlorothiazide+nebivolol. In case you feel dizzy or lightheaded, rest for some time until you feel better.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending on your current blood pressure readings, your doctor may lower your medicine dosage and not recommend discontinuing it.
The best time to take Hydrochlorothiazide+nebivolol is morning or evening as advised by the doctor based on your medical condition.
Hydrochlorothiazide+nebivolol can be taken with food or without food as recommended by the doctor.
Hydrochlorothiazide+nebivolol consists of hydrochlorothiazide and nebivolol. Hydrochlorothiazide is a thiazide diuretic and nebivolol is a beta blocker. This medication is used for the treatment of hypertension (high blood pressure) and reduces the risk of stroke in patients with high blood pressure.
Hydrochlorothiazide+nebivolol should be taken orally. Swallow the medicine as a whole with water, do not crush, break or chew it.
The side effects of Hydrochlorothiazide+nebivolol include constipation, diarrhoea, nausea, fatigue, headache, dizziness, decreased potassium level in the blood, altered blood lipid level, increased blood uric acid, increased calcium level in blood, breathlessness, swelling of hands & feet, paraesthesia (burning sensation of the skin), and decreased magnesium level in the blood. Consult the doctor if any of these side effects persist or worsen.
You should be cautious while taking Hydrochlorothiazide+nebivolol if you have kidney disease, liver disease, asthma, diabetes, eye problem (glaucoma), increased uric acid level (gout), hyperlipidaemia (increased lipid level) or hyperthyroidism (increased thyroid level). Consult the doctor before taking Hydrochlorothiazide+nebivolol if you have any of these health conditions.
Consult the doctor before taking other medications with Hydrochlorothiazide+nebivolol, particularly diuretics, blood pressure-lowering medications (amiodarone, clonidine, diltiazem, amlodipine, digoxin, disopyramide), antispasmodic medications (baclofen), medications for mental illness (amisulpiride, haloperidol, chlorpromazine), depression medications (amitriptyline, paroxetine, fluoxetine), anti-cancer medications (cyclophosphamide, methotrexate, fluorouracil), mood stabilizers (lithium), angina medications (bepridil), blood sugar-lowering medications (insulin, metformin), gout medications (allopurinol, sulfinpyrazone, probenecid), and medications used to treat low blood pressure medications (noradrenaline).
Hydrochlorothiazide+nebivolol should be stored in a cool and dry place away from sunlight. Keep it out of sight and reach of children.
