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FOLLITROPIN ALFA+LUTROPIN ALFA

About

FOLLITROPIN ALFA+LUTROPIN ALFA belongs to a group of medicines called gonadotropins. It is for use in adult women (18 years old or above) who have low levels (severe deficiency) of “follicle-stimulating hormone” (FSH) and “luteinising hormone” (LH). These women are usually infertile. Female Infertility is a condition when a woman cannot become pregnant within a year of trying without the use of contraception.

The active ingredients in FOLLITROPIN ALFA+LUTROPIN ALFA are synthetic versions of the natural hormones FSH and LH. FSH increases egg production in your body. LH triggers your ovary to release a mature egg. FOLLITROPIN ALFA+LUTROPIN ALFA helps women with low levels of FSH and LH to produce a follicle by supplementing the missing hormones. Following an injection of FOLLITROPIN ALFA+LUTROPIN ALFA, an egg will be released. This assists women in becoming pregnant.

Experienced healthcare professionals will administer FOLLITROPIN ALFA+LUTROPIN ALFA in the hospital setup. Like all medicines, FOLLITROPIN ALFA+LUTROPIN ALFA can cause side effects, although not everybody gets them. In some cases, FOLLITROPIN ALFA+LUTROPIN ALFA may cause reactions at the injection site (such as pain, redness, bruising, swelling and/or itching), sacs of fluid within the ovaries (ovarian cysts), diarrhoea, breast pain, feeling sick or vomiting, abdominal or pelvic pain, and abdominal cramp or bloating. These side effects are usually mild and temporary. However, if the side effects persist or worsen, please consult your doctor.

It is recommended not to use if you are allergic to follicle-stimulating hormone (FSH), luteinising hormone (LH) or any of the other ingredients of this medicine or if you have a brain tumour (in your hypothalamus or pituitary gland) or if you have unexplained vaginal bleeding or if you have cancer in your ovaries, womb or breasts or if you have a condition that would make a normal pregnancy impossible, such as early menopause, malformed sex organs or benign tumours of the womb or if you have large ovaries or sacs of fluid within your ovaries (ovarian cysts) of unknown origin. So, let your doctor know about all your medical conditions.

Uses of FOLLITROPIN ALFA+LUTROPIN ALFA

Treatment of Female infertility

Medicinal Benefits

FOLLITROPIN ALFA+LUTROPIN ALFA contains Follicle Stimulating Hormone and Luteinizing Hormone. FSH increases egg production in your body. LH triggers your ovary to release a mature egg. FOLLITROPIN ALFA+LUTROPIN ALFA helps women with low levels of FSH and LH to produce a follicle by supplementing the missing hormones. Following an injection of FOLLITROPIN ALFA+LUTROPIN ALFA, an egg will be released. This assists women in becoming pregnant.

Directions for Use

FOLLITROPIN ALFA+LUTROPIN ALFA will be administered by a trained healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of FOLLITROPIN ALFA+LUTROPIN ALFA

  • Reactions at the injection site (such as pain, redness, bruising, swelling and/or itching)
  • Sacs of fluid within the ovaries (ovarian cysts)
  • Diarrhoea
  • Breast pain
  • Feeling sick or vomiting
  • Abdominal or pelvic pain
  • Abdominal cramp or bloating

In-Depth Precautions and Warning

Drug Warnings

Before receiving FOLLITROPIN ALFA+LUTROPIN ALFA, inform your doctor if you have a known allergy to any medicines. Inform your doctor about your complete medical and medication history before receiving FOLLITROPIN ALFA+LUTROPIN ALFA to rule out any side effects, especially if you or any member of your family has porphyria (an inability to break down porphyrins that can be handed down from parents to children). Inform your doctor right away if your skin becomes brittle and easily blistered, particularly if it has been exposed to sunlight regularly or if you get stomach, arm, or leg pain. In the event of any of the events mentioned above, your doctor may advise you to discontinue treatment.

Drug Interactions

Drug-Drug Interactions: FOLLITROPIN ALFA+LUTROPIN ALFA interacts with certain medications used in fertility treatment to prevent premature ovulation (e.g. ganirelix).

Drug-Food Interactions: Limit or avoid the consumption of alcohol.

Drug-Disease Interactions: FOLLITROPIN ALFA+LUTROPIN ALFA potentially interacts with various

disease conditions such as a brain tumour (in your hypothalamus or pituitary gland), unexplained vaginal bleeding, cancer in your ovaries, womb or breasts, early menopause, malformed sex organs or benign tumours of the womb or if you have large ovaries or sacs of fluid within your ovaries (ovarian cysts) of unknown origin, adrenal dysfunction, thyroid dysfunction, and tumours.

Drug-Drug Interactions Checker List:

  • GANIRELIX
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is unknown whether FOLLITROPIN ALFA+LUTROPIN ALFA interacts with alcohol. However, as a precautionary measure, it is advisable not to take or limit alcohol.

    • Safety Warning

      Pregnancy

      unsafe

      Do not use FOLLITROPIN ALFA+LUTROPIN ALFA if you are pregnant. You may need to have a negative pregnancy test before starting this treatment.

    • Safety Warning

      Breast Feeding

      caution

      Your healthcare provider should decide if you will take FOLLITROPIN ALFA+LUTROPIN ALFA or breastfeed. You should not do both.

    • Safety Warning

      Driving

      safe if prescribed

      FOLLITROPIN ALFA+LUTROPIN ALFA does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      Limited information is available about using FOLLITROPIN ALFA+LUTROPIN ALFA in patients with liver disease. Inform your doctor before receiving FOLLITROPIN ALFA+LUTROPIN ALFA if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Kidney

      caution

      Limited information is available about using FOLLITROPIN ALFA+LUTROPIN ALFA in patients with kidney disease. Inform your doctor before receiving FOLLITROPIN ALFA+LUTROPIN ALFA if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Children

      unsafe

      FOLLITROPIN ALFA+LUTROPIN ALFA is not intended for use in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Consume a healthy diet rich in fibre and proteins and low in carbohydrates and fats. 
    • Avoid processed or high-sugar foods. 
    • Stay active and shed excess weight if you are overweight or obese. Do not perform intense exercises as they may negatively impact your reproductive health. Increase the intensity of exercise gradually.
    • Being underweight may also reduce your chances of getting pregnant. So, prepare a diet chart that can help you gain weight healthily. 
    • Avoid stress, as it may decrease your chances of getting pregnant. Try relaxation techniques and receive support and counselling if necessary. 
    • Limit alcohol and caffeine intake.
    • Quit smoking.

    Special Advise

    Patients Concern

    Disease/Condition Glossary

    Female Infertility: When a woman cannot become pregnant within a year of trying without the use of contraception, then the condition is called female infertility. If a woman gets pregnant but experiences miscarriages or stillbirths, it is also included in infertility. It can occur due to ovulation disorders (problems with ovaries), fallopian tube damage, and uterus or cervix problems. The risk factors can be age, being overweight or obese, smoking, alcoholism, and the presence of sexually transmitted infections.

    FAQs

    FOLLITROPIN ALFA+LUTROPIN ALFA is used to treat Female infertility.

    FOLLITROPIN ALFA+LUTROPIN ALFA contains Follicle Stimulating Hormone and Luteinizing Hormone. FSH increases egg production in your body. LH causes your ovary to release a mature egg. By replenishing the missing hormones, FOLLITROPIN ALFA+LUTROPIN ALFA assists women with low FSH and LH levels in producing follicles. Following an injection of FOLLITROPIN ALFA+LUTROPIN ALFA, an egg will be released. This helps women become pregnant.

    FOLLITROPIN ALFA+LUTROPIN ALFA is contraindicated to use in populations of those who are suffering from unexplained vaginal bleeding.

    Treatment with hormones such as FOLLITROPIN ALFA+LUTROPIN ALFA may enhance the likelihood of multiple pregnancies (twins, triplets, etc.). Multiple pregnancies might result in medical concerns for both you and your children. You can lower the risk of multiple pregnancies by taking FOLLITROPIN ALFA+LUTROPIN ALFA at the proper times.

    Available Medicines for

    FOLLITROPIN ALFA+LUTROPIN ALFA

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