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Ezetimibe+pitavastatin

About Ezetimibe+pitavastatin

Ezetimibe+pitavastatin is used to lower bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. High cholesterol, also known as Hypercholesterolemia, occurs when the unhealthy cholesterol balance is excessed in the blood. When the cholesterol level is high in the blood, your arteries get narrowed and clogged, contributing to heart diseases like stroke and heart attack.

Ezetimibe+pitavastatin is a combination of Ezetimibe and Pitavastatin. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Pitavastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. 

Take Ezetimibe+pitavastatin as prescribed. Your doctor will advise you on how often you should take it based on your medical condition. Sometimes, Ezetimibe+pitavastatin may cause common side effects such as headache, muscle pain or tenderness, joint pain, and weakness. Most of these side effects of Ezetimibe+pitavastatin do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Ezetimibe, Pitavastatin or any other medicines, please tell your doctor. If you are aged 65 years or older or drink excessive amounts of alcohol, please inform your doctor. Avoid using Ezetimibe+pitavastatin if you are pregnant. Also, you are advised to use effective birth control measures while taking Ezetimibe+pitavastatin to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. If you have any concerns regarding the use of Ezetimibe+pitavastatin for children, consult a doctor. If you feel dizzy or sleepy after taking Ezetimibe+pitavastatin, avoid driving or operating machinery. Maintain a cholesterol-lowering diet along with Ezetimibe+pitavastatin for effective results.

Uses of Ezetimibe+pitavastatin

Treatment of High Cholesterol

Medicinal Benefits

Ezetimibe+pitavastatin belongs to the class of medicines called antihyperlipidemic drugs or cholesterol-lowering agents. It contains Ezetimibe and Pitavastatin, which are used to lower the levels of bad cholesterol and triglycerides (type of fat) and increase good cholesterol levels. This reduces the risk of heart attack and stroke in future. Ezetimibe reduces the cholesterol absorbed in the digestive tract. Simvastatin inhibits the production of cholesterol your body makes by itself. Also, it reduces the risk of stroke or heart attack by decreasing the excess cholesterol deposition in the major blood vessels of the brain and heart. Ezetimibe+pitavastatin is used for patients whose cholesterol levels cannot be controlled by diet and exercise alone.

Directions for Use

Take it with or without food as advised by your doctor. Swallow it whole with a glass of water. Do not break, crush, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ezetimibe+pitavastatin

  • Headache
  • Muscle pain or tenderness
  • Joint pain
  • Weakness

Drug Warnings

If you are allergic to Ezetimibe, Pitavastatin or any other medicines, please tell your doctor. Your doctor may recommend a blood test before and after you start taking Ezetimibe+pitavastatin to check your liver function. If you are taking or have taken fusidic acid (antibiotic) orally or by injection in the last 7 days, inform your doctor, as the combination of fusidic acid and pitavastatin may lead to serious muscle problems (rhabdomyolysis). If you are aged 65 years or older, or drink excessive amounts of alcohol, please inform your doctor. Avoid using Ezetimibe+pitavastatin if you are pregnant. Also, you are advised to use effective birth control measures while taking Ezetimibe+pitavastatin to avoid pregnancy. Please inform your doctor if you are a breastfeeding mother. If you have any concerns regarding the use of Ezetimibe+pitavastatin for children, consult a doctor. If you feel dizzy or sleepy after taking Ezetimibe+pitavastatin, avoid driving or operating machinery. Maintain a cholesterol-lowering diet along with Ezetimibe+pitavastatin for effective results. If you have diabetes or are at risk of developing diabetes, your doctor will monitor you closely while on treatment with Ezetimibe+pitavastatin. You are likely to be at risk of developing diabetes if you have high levels of sugars and fats in the blood, high blood pressure and are overweight.

Drug Interactions

Drug-Drug Interaction: If you are taking immunosuppressant (ciclosporin), blood thinners (warfarin, acenocoumarol, phenprocoumon, fluindione), other cholesterol-lowering drugs (colestyramine, gemfibrozil, fenofibrate), antibiotics (erythromycin, rifampicin, fusidic acid), medicines used to treat HIV (lopinavir, darunavir, ritonavir, atazanavir, efavirenz), drugs used to treat hepatitis C (glecaprevir, pibrentasvir) or niacin (vitamin B3), inform your doctor before taking Ezetimibe+pitavastatin.

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Avoid taking Ezetimibe+pitavastatin if you have liver problems. If you have severe breathing problems, myasthenia (general muscle weakness), ocular myasthenia (eye muscle weakness), muscle problems, diabetes, thyroid, kidney or liver problems, inform your doctor before taking Ezetimibe+pitavastatin.

Drug-Drug Interactions Checker List:

  • CICLOSPORIN
  • WARFARIN
  • ACENOCOUMAROL
  • PHENPROCOUMON
  • FLUINDIONE
  • CHOLESTYRAMINE
  • GEMFIBROZIL
  • FENOFIBRATE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • FUSIDIC ACID
  • LOPINAVIR
  • DARUNAVIR
  • RITONAVIR
  • ATAZANAVIR
  • EFAVIRENZ
  • GLECAPREVIR
  • PIBRENTASVIR
  • NIACIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid alcohol consumption with Ezetimibe+pitavastatin as it may increase the risk of liver damage. Inform your doctor if you drink excessive amounts of alcohol.

    • Safety Warning

      Pregnancy

      unsafe

      Ezetimibe+pitavastatin is not recommended for use during pregnancy as it may harm your unborn baby. If you get pregnant while on treatment with Ezetimibe+pitavastatin, stop using it immediately and seek medical advice.

    • Safety Warning

      Breast Feeding

      consult your doctor

      It is unknown whether Ezetimibe+pitavastatin is excreted in the breast milk. Therefore, if you are a breastfeeding mother, inform your doctor before taking Ezetimibe+pitavastatin.

    • Safety Warning

      Driving

      caution

      Ezetimibe+pitavastatin usually does not affect your ability to drive or operate machinery. However, if you feel dizzy or sleepy after taking Ezetimibe+pitavastatin, avoid driving or operating machinery.

    • Safety Warning

      Liver

      caution

      Ezetimibe+pitavastatin is contraindicated in patients with moderate or severe liver problems. Thus, if you have any liver problems, inform your doctor before taking this medicine.

    • Safety Warning

      Kidney

      consult your doctor

      If you have kidney problems, please inform your doctor before taking Ezetimibe+pitavastatin. Your doctor may adjust the dose based on your condition.

    • Safety Warning

      Children

      consult your doctor

      Please consult a doctor if you have any concerns regarding the use of Ezetimibe+pitavastatin for children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
    • Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts, cut-down beverages, and processed and sugary foods.
    • Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight. Obesity also raises bad cholesterol and lowers good cholesterol.
    • Avoid smoking and alcohol consumption.

    Special Advise

    If you experience unexplained muscle pain, tenderness, or weakness, consult your doctor immediately, as on rare occasions, muscle problems, including muscle breakdown resulting in kidney damage, can be serious and may become a potentially life-threatening condition.

    Patients Concern

    Disease/Condition Glossary

    High cholesterol: It is also known as Hypercholesterolemia and occurs when there is an excess of the unhealthy cholesterol balance in the blood. When there is a high level of cholesterol in the blood, your arteries get narrowed and clogged, finally contributing to heart diseases like stroke and heart attack. Eating high-fat or high-cholesterol-containing food/drinks and genetic factors are the primary causes of high cholesterol. Two types of cholesterol are found in our body: good cholesterol (high-density lipoprotein) and bad cholesterol (low-density lipoprotein). Good cholesterol is good for our heart and helps reduce the bad cholesterol in our body. On the other hand, excess bad cholesterol (LDL) leads to the risk of heart diseases like heart attack and stroke.

    FAQs

    Ezetimibe+pitavastatin is used to treat High Cholesterol.

    Ezetimibe+pitavastatin contains Ezetimibe and Pitavastatin. Ezetimibe works by reducing the cholesterol absorbed in the digestive tract. Pitavastatin works by inhibiting the production of cholesterol your body makes by itself. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.

    Ezetimibe+pitavastatin may increase the risk of rhabdomyolysis (the breakdown of muscle tissue) in some patients. It is not common for everyone who takes Ezetimibe+pitavastatin. However, if you experience unexplained muscle pain, weakness or tenderness, especially along with fever, dark-coloured urine or unusual tiredness, please consult your doctor immediately.

    You are not recommended to stop taking Ezetimibe+pitavastatin without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Ezetimibe+pitavastatin for as long as your doctor has prescribed it, and if you experience any difficulty while taking Ezetimibe+pitavastatin, please consult your doctor so that the dose may be gradually reduced.

    Available Medicines for

    Ezetimibe+pitavastatin

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