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Chlorpheniramine+dextromethorphan+phenylephrine

About Chlorpheniramine+dextromethorphan+phenylephrine

Chlorpheniramine+dextromethorphan+phenylephrine is used to treat dry cough. Coughing (dry or productive) is the body's way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. A dry cough is tickly and doesn't produce any viscous or thick mucus, while a chesty cough (wet cough) means mucus or sputum is created to help clear the airways.

Chlorpheniramine+dextromethorphan+phenylephrine is a combination of three drugs: Chlorpheniramine, Phenylephrine, and Dextromethorphan. Chlorpheniramine works by blocking the action of histamine. Phenylephrine helps in shrinking the blood vessels located in the nasal passage. Dextromethorphanworks by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce a cough.

Some people may experience dry mouth, throat, or nose, as well as drowsiness, blurred vision, constipation, dizziness, restlessness, or excitation. Most of these side effects do not require medical attention and typically resolve on their own over time. However, if the side effects persist or worsen, please consult your doctor.

If you are pregnant or breastfeeding, it is advised to inform your doctor before using Chlorpheniramine+dextromethorphan+phenylephrine. Avoid using Chlorpheniramine+dextromethorphan+phenylephrine if you have taken monoamine oxidase inhibitors in the past 14 days. If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, inform your doctor before taking it.

Uses of Chlorpheniramine+dextromethorphan+phenylephrine

Chlorpheniramine+dextromethorphan+phenylephrine is used to treat dry cough. The detailed uses of Chlorpheniramine+dextromethorphan+phenylephrine are as follows:
• Cough Relief: Chlorpheniramine+dextromethorphan+phenylephrine is designed to provide cough relief, especially for dry coughs, by utilizing its antitussive properties to calm throat irritation and reduce the urge to cough.
• Allergy Relief: Chlorpheniramine+dextromethorphan+phenylephrine can help to alleviate allergy symptoms like runny nose and sneezing, offering relief for individuals who experience seasonal allergic reactions.
• Soothing Sore Throat: Chlorpheniramine+dextromethorphan+phenylephrine helps to calm a sore throat caused by coughing or irritation, making swallowing easier and reducing throat discomfort.
• Decongestant: Chlorpheniramine+dextromethorphan+phenylephrine contains Phenylephrine, a decongestant that reduces nasal congestion by shrinking swollen blood vessels in the nasal passages.

Medicinal Benefits

  • Chlorpheniramine+dextromethorphan+phenylephrine contains Chlorpheniramine maleate, Phenylephrine, and Dextromethorphan used to treat dry cough. 
  • Chlorpheniramine maleate helps to provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps in shrinking the blood vessels located in the nasal passage, thereby reducing the stuffy nose. 
  • Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.
  • Thus, Chlorpheniramine+dextromethorphan+phenylephrine helps to relieve overall cough, cold and allergic symptoms.

Directions for Use

  • Chlorpheniramine+dextromethorphan+phenylephrine can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Measure the prescribed dose using a measuring cup and administer it orally.
  • Avoid using regular household spoons, as they may not measure the dose correctly.
  • Shake te bottle well before use.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Chlorpheniramine+dextromethorphan+phenylephrine

  • Dry mouth, throat or nose
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Headache
  • Constipation
  • Restlessness or excitation
  • Loss of appetite

Drug Warnings

  • If you are allergic to Chlorpheniramine+dextromethorphan+phenylephrine or any other medicines, please tell your doctor.
  • If you are pregnant or breastfeeding, it is advised to inform your doctor before using it.
  • Chlorpheniramine+dextromethorphan+phenylephrine is not recommended for children below 12 years of age.
  • If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking this medicine.
  • Avoid taking Chlorpheniramine+dextromethorphan+phenylephrine if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days.
  • If you have glaucoma, urinary problems, enlarged prostate, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), cough with mucus or cough caused by asthma, smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), inform your doctor before taking Chlorpheniramine+dextromethorphan+phenylephrine.

Drug Interactions

Drug-Drug Interactions: Chlorpheniramine+dextromethorphan+phenylephrine may have interaction with anti-allergic drugs (diphenhydramine), anti-psychotic (escitalopram, desvenlafaxine, vilazodone), pain killer (aspirin), cold medicines (acetaminophen), antibiotics (amoxicillin), anti-depressants (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), beta-blockers (metoprolol, atenolol), muscle relaxants (carisoprodol, cyclobenzaprine).

Drug-Food Interactions: Chlorpheniramine+dextromethorphan+phenylephrine may interact with alcohol. Therefore, avoid alcohol consumption with Chlorpheniramine+dextromethorphan+phenylephrine as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

Drug-Disease Interactions: Chlorpheniramine+dextromethorphan+phenylephrine is known to interact in patients with liver or kidney disease, asthma, diabetes, glaucoma, cardiovascular diseases, enlarged prostate gland, chronic bronchitis or emphysema (a lung condition causing shortness of breath).

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • ESCITALOPRAM
  • DESVENLAFAXINE
  • VILAZODONE
  • ACETAMINOPHEN
  • AMOXICILLIN
  • LINEZOLID
  • PHENELZINE
  • SELEGILINE
  • RASAGILINE
  • ISOCARBOXAZID
  • TRANYLCYPROMINE
  • METOPROLOL
  • ATENOLOL
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol with Chlorpheniramine+dextromethorphan+phenylephrine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Chlorpheniramine+dextromethorphan+phenylephrine.

    • Safety Warning

      Pregnancy

      caution

      The safety of Chlorpheniramine+dextromethorphan+phenylephrine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether Chlorpheniramine+dextromethorphan+phenylephrine is excreted in human milk. Chlorpheniramine+dextromethorphan+phenylephrine is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

    • Safety Warning

      Driving

      caution

      Chlorpheniramine+dextromethorphan+phenylephrine may cause dizziness or drowsiness in some people. Therefore, drive only if you are alert after taking Chlorpheniramine+dextromethorphan+phenylephrine.

    • Safety Warning

      Liver

      caution

      Take Chlorpheniramine+dextromethorphan+phenylephrine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Chlorpheniramine+dextromethorphan+phenylephrine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Chlorpheniramine+dextromethorphan+phenylephrine is not recommended for children below 12 years of age. However, please consult a doctor before using Chlorpheniramine+dextromethorphan+phenylephrine in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. 
    • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
    • Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

    Special Advise

    • Chlorpheniramine+dextromethorphan+phenylephrine may contain phenylalanine, so check the medication label if you have phenylketonuria (PKU).
    • Do not use Chlorpheniramine+dextromethorphan+phenylephrine only to make a child sleepy.
    • Contact a doctor if your symptoms do not improve even after 7 days.
    • Contact a doctor immediately if you develop fever, rash or headaches after taking Chlorpheniramine+dextromethorphan+phenylephrine. 

    Patients Concern

    Disease/Condition Glossary

    Cough: Coughing is the body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an infection in the respiratory tract. If you are coughing thick, solid white mucus, you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.

    FAQs

    Chlorpheniramine+dextromethorphan+phenylephrine is used to treat dry cough.

    Chlorpheniramine+dextromethorphan+phenylephrine is a combination drug, primarily used to treat dry cough. Chlorpheniramine works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a 'decongestant' that helps in shrinking the blood vessels located in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough.

    Consuming alcohol, along with Chlorpheniramine+dextromethorphan+phenylephrine, may potentiate some of the pharmacologic effects of CNS-active agents. If used together, it may lead to symptoms like confusion, central nervous system depression, impairment of thinking and judgment.

    No, you should not take Chlorpheniramine+dextromethorphan+phenylephrine if you need to undergo surgery as it may lead to excessive drowsiness and sleepiness when given along with anesthesia. Please inform your doctor before surgery if you are taking Chlorpheniramine+dextromethorphan+phenylephrine as the doctor may stop it 72 hours before the surgery.

    It is not recommended to take Chlorpheniramine+dextromethorphan+phenylephrine along with any anti-depressant medication, especially MAO inhibitors (linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine), as it may lead to unpleasant side-effects or any drug interaction. Also, Chlorpheniramine+dextromethorphan+phenylephrine should be taken at least 15 days after your last dose of anti-depressants.

    Available Medicines for

    Chlorpheniramine+dextromethorphan+phenylephrine

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