Chlorpheniramine+paracetamol+phenylephrine+caffeine
About Chlorpheniramine+paracetamol+phenylephrine+caffeine
Chlorpheniramine+paracetamol+phenylephrine+caffeine is used to treat the common cold and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus.' The virus attacks the body through the mouth, nose, or eyes and spreads quickly through droplets in the air when a person who is sick sneezes, coughs, or talks.
Chlorpheniramine+paracetamol+phenylephrine+caffeine is composed of four medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing the stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Chlorpheniramine+paracetamol+phenylephrine+caffeine.
Your doctor will recommend how often you take Chlorpheniramine+paracetamol+phenylephrine+caffeine based on your medical condition. Some people may experience drowsiness, sleepiness, nausea, fatigue, difficulty in sleeping, and headache. Most of these side effects may not require medical attention and resolve gradually overtime. However, if the side effects persist or worsen, consult the doctor.
Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Chlorpheniramine+paracetamol+phenylephrine+caffeine. If you have high blood pressure (hypertension), liver or kidney disease, or coronary artery disease (heart disease), avoid using Chlorpheniramine+paracetamol+phenylephrine+caffeine as it may worsen your existing condition and symptoms. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Intake of more than 4 gm of paracetamol can damage your liver, so it is better to avoid the use of Chlorpheniramine+paracetamol+phenylephrine+caffeine in severe liver damage. Cetirizine present in the Chlorpheniramine+paracetamol+phenylephrine+caffeine can make you sleepy, so do not drive or operate heavy machinery after taking Chlorpheniramine+paracetamol+phenylephrine+caffeine. Phenylephrine present in Chlorpheniramine+paracetamol+phenylephrine+caffeine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers).
Uses of Chlorpheniramine+paracetamol+phenylephrine+caffeine
Medicinal Benefits
Chlorpheniramine+paracetamol+phenylephrine+caffeine is primarily used to treat common cold symptoms and allergic symptoms like sneezing, watery eyes, or itchy/watery nose and throat. It is composed of four medicines: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever. Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Chlorpheniramine+paracetamol+phenylephrine+caffeine.
Directions for Use
Storage
Side Effects of Chlorpheniramine+paracetamol+phenylephrine+caffeine
- Drowsiness
- Nervousness
- Headache
- Dizziness
- Insomnia (difficulty falling or staying asleep)
- Allergic reactions
Drug Warnings
If you are allergic to Chlorpheniramine+paracetamol+phenylephrine+caffeine or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using Chlorpheniramine+paracetamol+phenylephrine+caffeine. Do not use Chlorpheniramine+paracetamol+phenylephrine+caffeine in breastfeeding mothers without a doctor’s advice as it contains caffeine, which may be excreted in breast milk and cause harm to the baby. Chlorpheniramine+paracetamol+phenylephrine+caffeine is not recommended for children below 4 years. Please do not take more than the prescribed dose of Chlorpheniramine+paracetamol+phenylephrine+caffeine as it may cause liver damage and can be lethal. If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking Chlorpheniramine+paracetamol+phenylephrine+caffeine. Do not take Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days. Also, avoid intake of chocolate, alcohol, and caffeine-containing beverages like coffee as they may increase the risk of severity of side effects. Do not take Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Cetirizine present in the Chlorpheniramine+paracetamol+phenylephrine+caffeine can make you sleepy, so do not drive or operate heavy machinery after taking Chlorpheniramine+paracetamol+phenylephrine+caffeine. Phenylephrine present in Chlorpheniramine+paracetamol+phenylephrine+caffeine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage) including Raynaud's phenomenon (decreased blood flow to the fingers).
Drug Interactions
Drug-Drug Interaction: Chlorpheniramine+paracetamol+phenylephrine+caffeine may interact with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, imipramine, amitriptyline), anticonvulsants (clonazepam), antianxiety drug (alprazolam), cough suppressants (dextromethorphan), bronchodilator (albuterol), sleeping agent (ramelteon), pain killers (ibuprofen).
Drug-Food Interaction: Avoid intake of Chlorpheniramine+paracetamol+phenylephrine+caffeine with caffeine-containing foods (like coffee) and alcoholic beverages as they may cause increased drowsiness, dizziness, and difficulty in concentrating.
Drug-Disease Interaction: If you have high blood pressure, diabetes, hyperthyroidism (overactive thyroid), asthma, chronic obstructive pulmonary disease (COPD), stomach ulcer, Raynaud's phenomenon (decreased blood flow to the fingers), enlarged prostate gland, kidney, liver, heart, or urinary problems, inform your doctor before taking Chlorpheniramine+paracetamol+phenylephrine+caffeine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Chlorpheniramine+paracetamol+phenylephrine+caffeine to avoid excessive drowsiness and sleepiness.
Pregnancy
cautionThe safety of Chlorpheniramine+paracetamol+phenylephrine+caffeine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionChlorpheniramine+paracetamol+phenylephrine+caffeine is known to pass through milk in small amounts. Use in breastfeeding women is not recommended as it may cause unpleasant side effects to the baby like unusual irritability, excitement.
Driving
unsafeChlorpheniramine+paracetamol+phenylephrine+caffeine is known to cause drowsiness, so please do not drive or operate any machinery which requires concentration.
Liver
cautionTake Chlorpheniramine+paracetamol+phenylephrine+caffeine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Chlorpheniramine+paracetamol+phenylephrine+caffeine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
cautionChlorpheniramine+paracetamol+phenylephrine+caffeine is not recommended for children below 4 years. However, it can be given to the children more than 4 years of age only if the doctor has prescribed it.
Habit Forming
Diet & Lifestyle Advise
Wash your hands with soap and water regularly to prevent the spread of germs.
Eat plenty of foods rich in good bacteria like yogurt to improve overall health.
Drink plenty of fluids to avoid dehydration and keep the throat lubricated.
Gargle with salt water for relief from sore throat.
Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylephrine+caffeine as it may cause tiredness, drowsiness, or lack of concentration.
Special Advise
Avoid alcohol consumption with Chlorpheniramine+paracetamol+phenylephrine+caffeine as it may cause tiredness, drowsiness, or lack of concentration.
Do not take Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
Please inform your doctor if you are pregnant or breastfeeding before starting Chlorpheniramine+paracetamol+phenylephrine+caffeine as it contains caffeine, which can pass in the breast milk, which may have a stimulating effect on a breastfed child.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected by having 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The common cold symptoms include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.
Allergies: These occur when foreign elements that cause allergy-causing agents (allergens) attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose, throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet dander, dust, pollen hairs, seasonal allergies like hay fever, etc.
FAQs
Chlorpheniramine+paracetamol+phenylephrine+caffeine is used to treat the common cold and allergy symptoms like sneezing, watery eyes, or itchy/watery nose and throat.Â
Chlorpheniramine+paracetamol+phenylephrine+caffeine is composed of four medicines, namely: Chlorpheniramine (anti-histamine), Phenylephrine (decongestant), Paracetamol (mild analgesic and antipyretic), and Caffeine (a stimulant). Chlorpheniramine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.  Caffeine acts as a common stimulant, which decreases sleepiness caused by Chlorpheniramine and speeds up the action of all the medicines present in Chlorpheniramine+paracetamol+phenylephrine+caffeine.
Do not use Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have used an MAO inhibitor in the past 14 days, like isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, or tranylcypromine. Tell your doctor before taking Chlorpheniramine+paracetamol+phenylephrine+caffeine if you have nausea, stomach pain, itchy skin, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes). In rare cases, paracetamol present in Chlorpheniramine+paracetamol+phenylephrine+caffeine may cause a severe skin allergic reaction. So, if you observe any skin blisters or redness, or rash, immediately contact your doctor and stop taking Chlorpheniramine+paracetamol+phenylephrine+caffeine.
Chlorpheniramine+paracetamol+phenylephrine+caffeine contains caffeine. So, avoid taking medicines or food containing caffeine like cold drinks, coffee, chocolate, and tea. Also, avoid consumption of alcohol while taking Chlorpheniramine+paracetamol+phenylephrine+caffeine as it might increase drowsiness.
You are not recommended to stop taking Chlorpheniramine+paracetamol+phenylephrine+caffeine without consulting your doctor as it may worsen the cough or cause recurring cough. Therefore, take Chlorpheniramine+paracetamol+phenylephrine+caffeine for as long as your doctor has prescribed it, and if you experience any difficulty while taking Chlorpheniramine+paracetamol+phenylephrine+caffeine, please consult your doctor.
No, it is not advisable to breastfeed while using Chlorpheniramine+paracetamol+phenylephrine+caffeine as it contains an antihistamine drug Chlorpheniramine, and also it contains caffeine, which can pass through the breast milk and may harm the baby.
Chlorpheniramine+paracetamol+phenylephrine+caffeine is a combination medication containing four active ingredients: Chlorpheniramine (antihistamine), Phenylephrine (decongestant), Paracetamol (mild pain reliever and fever reducer), and Caffeine (stimulant). It treats common cold and allergic symptoms such as sneezing, runny nose, and itchy throat.
Store Chlorpheniramine+paracetamol+phenylephrine+caffeine in by keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, place it in a plastic bag and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.
In rare cases, some side effects may become serious, such as severe headaches, allergic reactions, fatigue, severe stomach problems, vomiting, difficulty sleeping, liver problems, and kidney issues. If you experience any of these symptoms, seek medical attention immediately.
No, taking a higher than the recommended dose of Chlorpheniramine+paracetamol+phenylephrine+caffeine will not be more effective and may increase the risk of side effects.
Yes, some contraindications are associated with using Chlorpheniramine+paracetamol+phenylephrine+caffeine; it should be used cautiously in certain situations. People who are allergic to any of its ingredients should inform their doctor. It should be used with caution in pregnancy, breastfeeding women, and in children under 4 years. Additionally, individuals with certain medical conditions, such as high blood pressure, diabetes, hyperthyroidism, asthma, and kidney or liver problems, should inform their doctor before taking this medication.
The common side effects of Chlorpheniramine+paracetamol+phenylephrine+caffeine are drowsiness, sleepiness, nausea, fatigue, allergic reactions, difficulty sleeping, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.
