CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE
About
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE is a combination medicine used to treat irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and symptoms related to intestinal infection. Irritable bowel syndrome is a common disease that affects the large intestine. Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Enterocolitis is an inflammation of the digestive tract caused by bacteria, virus, parasites, fungus, or other causes.
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE contains Clidinium (anti-cholinergic), Chlordiazepoxide (benzodiazepine), Dicyclomine (anti-cholinergic), and Ranitidine (H2 blocker). Clidinium and Dicyclomine relax the stomach and intestine muscles, thereby providing relief from cramps, discomfort, bloating, and pain. Chlordiazepoxide decreases abnormal and excess activity of the nerve cells in the brain by increasing a chemical messenger called GABA. Ranitidine works by blocking H2 receptors, reducing gastric acid secretion and providing relief from acidity and heartburn.
Take CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as prescribed. Swallow CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as a whole with a glass of water; do not chew or crush it. You are advised to take CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may cause certain common side-effects such as weakness, tiredness, dry mouth, nausea, constipation, and drowsiness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Please do not stop taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE on your own as it might cause withdrawal symptoms. Avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are pregnant or planning for pregnancy, as it may cause congenital disabilities (birth defects). CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may pass into breastmilk, so avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are breastfeeding. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may cause drowsiness, blurred vision or vision changes; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as it may cause increased drowsiness. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE should not be given to children as safety and effectiveness were not established.
Uses of CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE
Medicinal Benefits
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE is a combination medicine used to treat irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and symptoms related to intestinal infection. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE is a combination of four drugs, namely: Clidinium (anti-cholinergic), Chlordiazepoxide (benzodiazepine), Dicyclomine (anti-cholinergic), and Ranitidine (H2 blocker). Clidinium and Dicyclomine work by stopping muscle contractions by relaxing the muscles in the stomach and intestine, thereby providing relief from cramps, discomfort, bloating, and pain. Chlordiazepoxide decreases abnormal and excess activity of the nerve cells in the brain by increasing the action of a chemical messenger called GABA. Ranitidine works by blocking H2 receptors, thereby reducing gastric acid secretion and providing relief from acidity and heartburn.
Directions for Use
Storage
Side Effects of CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE
- Weakness
- Tiredness
- Dry mouth
- Nausea
- Constipation
- Drowsiness
In-Depth Precautions and Warning
Drug Warnings
Do not take CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are allergic to any of its contents. Inform your doctor if you have glaucoma, enlarged prostate, bladder neck obstruction, vision problems, urination problems, depression, liver and kidney problems; if you are 65years or older; if you use opioid (narcotic) medicines such as codeine, hydrocodone, hydromorphone, methadone, morphine, oxycodone, and tramadol. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may be habit-forming, so inform your doctor if you have a history of drug addiction or abuse. Keep your doctor informed about all the medicines you are taking, including prescription, non-prescription medicines and herbal supplements. Please do not stop taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE on your own as it might cause withdrawal symptoms. Avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are pregnant or planning for pregnancy, as it may cause congenital disabilities (birth defects). CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may pass into breastmilk, so avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are breastfeeding. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may cause drowsiness, blurred vision or vision changes; do not drive or handle machinery unless you are alert. Avoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as it may cause increased drowsiness. CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE should not be given to children as safety and effectiveness were not established.
Drug Interactions
Drug-Drug Interactions: CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may interact with pain killers (codeine, hydrocodone, hydromorphone, methadone, morphine, oxycodone, tramadol, acetaminophen, ibuprofen), blood thinner (warfarin), anti-psychotic (chlorpromazine, fluphenazine, thioridazine), anti-depressants (isocarboxazid, phenelzine, selegiline, tranylcypromine, duloxetine, fluoxetine, sertraline), muscle relaxant (cyclobenzaprine), anti-convulsant (pregabalin, gabapentin), anti-anxiety (alprazolam), antihistamine (cetirizine, diphenhydramine), anti-hypertensive (metoprolol), anti-spasmodic (hyoscyamine), anti-diarrhoeal (loperamide), anti-emetic (promethazine), and vitamin (cyanocobalamin).
Drug-Food Interactions: Avoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as it may cause increased drowsiness.
Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeat), gastrointestinal obstruction, glaucoma, infectious diarrhoea, acute alcohol intoxication, drug dependence, autonomic neuropathy (nerve damage), respiratory depression, seizures, prolonged low blood pressure, depression, psychoses, obesity, high blood pressure, porphyria, fever, gastrointestinal bleeding, tardive dyskinesia (uncontrollable movements of the face), liver or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE as it may cause increased drowsiness.
Pregnancy
unsafeConsult your doctor before taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are pregnant or planning for pregnancy, as CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may cause congenital disabilities (birth defects).
Breast Feeding
unsafeConsult your doctor before taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you are breastfeeding as CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may pass into breastmilk.
Driving
unsafeCHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may cause drowsiness, blurred vision or vision changes. Do not drive or handle machinery unless you are alert.
Liver
cautionDose adjustment may be needed. Consult your doctor before taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed. Consult your doctor before taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE if you have kidney impairment or any concerns regarding this.
Children
unsafeCHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE should not be given to children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
- Maintain a healthy weight by regular exercising.
- Avoid carbonated and caffeinated beverages.
- Practise relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid deep-fried and spicy foods.
- Foods containing probiotics may help in providing relief from gas and bloating.
Special Advise
- Do not stop taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE on your own as it may cause withdrawal symptoms.
- Take CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE only as prescribed by the doctor. Do not exceed the dose and duration as CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE may be habit-forming, especially in people with a history of drug addiction or abuse, and in those who are alcoholic.
Patients Concern
Disease/Condition Glossary
Irritable bowel syndrome (IBS): It is a common disease that affects the large intestine. IBS is also known as spastic colon, irritable colon, spastic colitis, and mucous colitis. An irritable bowel syndrome is a group of intestinal symptoms that occur together. The exact cause is unknown, but common causes of IBS are acidity, stress, carbonated foods and beverages, irregular hormone levels, and certain food and medications. Symptoms include abdominal pain, cramps, bloating, gas, constipation, and/or diarrhoea.
Peptic ulcers: Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
Enterocolitis: It is an inflammation of the digestive tract caused by bacteria, viruses, parasites, fungi, or other causes. Symptoms include abdominal pain, nausea, vomiting, mucous-like discharge from the rectum, loss of appetite, and diarrhoea.
FAQs
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE is used to treat irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and symptoms related to intestinal infection.
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE contains Clidinium, Chlordiazepoxide, Dicyclomine, and Ranitidine. Clidinium and Dicyclomine work by stopping muscle contractions by relaxing the stomach and intestine muscles, thereby providing relief from cramps, discomfort, bloating, and pain. Chlordiazepoxide decreases abnormal and excess activity of the nerve cells in the brain by increasing a chemical messenger called GABA. Ranitidine works by blocking H2 receptors, reducing gastric acid secretion and providing relief from acidity and heartburn.
Constipation might be a side-effect of CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE. Drink enough fluids and eat fibre-rich food if you experience constipation. Consult your doctor if the condition persists or worsens.
Please do not stop taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE on your own as it might cause withdrawal symptoms such as fits, shaking, muscle cramps, stomach cramps, depression, vomiting, sleeping problems, and sweating. Consult your doctor if you experience any difficulty while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE, the doctor may gradually reduce the dose.
Dry mouth could be a side-effect of CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Irregular menstrual cycle might be a side-effect of CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE. Consult your doctor if you miss your periods or if you have irregular periods while taking CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE.
CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE contains chlordiazepoxide which is a habit-forming drug. Habit-forming could occur, especially in people with a history of drug addiction or abuse and in those who are alcoholic. Take CHLORDIAZEPOXIDE+CLIDINIUM+DICYCLOMINE+RANITIDINE only as prescribed by the doctor and do not exceed the dose and duration.
