CEFTIZOXIME+SULBACTAM
About
CEFTIZOXIME+SULBACTAM belongs to the group of medicines called antibiotics. It is used to treat a wide variety of bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.
CEFTIZOXIME+SULBACTAM contains Ceftizoxime (third-generation cephalosporin antibiotic) and Sulbactam (beta-lactamase inhibitor). It works by inhibiting the synthesis of the bacterial cell wall (a protective covering) that is necessary for their survival. This causes damage to the bacterial cell wall and eventually leads to the death of the bacterial cell. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Together, CEFTIZOXIME+SULBACTAM helps treat bacterial infections.
CEFTIZOXIME+SULBACTAM will be administered by a healthcare professional; do not self-administer. In some cases, CEFTIZOXIME+SULBACTAM may cause injection site reactions, diarrhoea, nausea, vomiting, headache, rash, stomach upset, and indigestion. Most of these side effects of CEFTIZOXIME+SULBACTAM do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Let your doctor know about your medical and medication history to avoid the occurrence of potential interactions. CEFTIZOXIME+SULBACTAM should only be given during pregnancy when the need has been established. Hence, inform your doctor if you are pregnant, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of CEFTIZOXIME+SULBACTAM therapy against the risk to your baby. Breastfeeding should be avoided unless instructed by the doctor. Consumption of alcohol should be avoided while on treatment with CEFTIZOXIME+SULBACTAM.
Uses of CEFTIZOXIME+SULBACTAM
Medicinal Benefits
CEFTIZOXIME+SULBACTAM contains Ceftizoxime and Sulbactam. Ceftizoxime is a third-generation cephalosporin antibiotic, and Sulbactam is a beta-lactamase inhibitor. It acts by blocking the synthesis of the bacterial cell wall, which is required for their survival. This damages the bacterial cell wall and eventually kills the bacterial cell. Sulbactam reduces bacterial resistance while increasing the activity of Ceftizoxime against bacteria. Together, CEFTIZOXIME+SULBACTAM helps to treat bacterial infections.
Directions for Use
Storage
Side Effects of CEFTIZOXIME+SULBACTAM
- Injection site reactions
- Diarrhoea
- Nausea
- Vomiting
- Headache
- Rash
- Stomach upset
- Indigestion
In-Depth Precautions and Warning
Drug Warnings
Before taking the CEFTIZOXIME+SULBACTAM, inform your doctor about all of your medical problems, sensitivities, and drugs. If you are pregnant or breastfeeding, check with your doctor before taking CEFTIZOXIME+SULBACTAM. For effective outcomes, it is recommended that you complete the entire course of CEFTIZOXIME+SULBACTAM as prescribed by your doctor. If you are received or scheduled for immunizations, inform your doctor. CEFTIZOXIME+SULBACTAM should be used cautiously in people with Clostridium difficile-associated diarrhoea.
Drug Interactions
Drug-Drug Interaction: CEFTIZOXIME+SULBACTAM may interact with immunosuppressive medications (e.g. Mycophenolate mofetil, Mycophenolic acid) and certain vaccinations (BCG vaccine, Cholera vaccine live, Typhoid vaccine live).
Drug-Food Interaction: Alcohol consumption should be avoided.
Drug-Disease Interaction: CEFTIZOXIME+SULBACTAM may interact with certain disease conditions, including colitis (inflammation in your colon), renal dysfunction, renal impairment, dialysis, liver disease, and seizure disorders. So, inform your doctor about your medical conditions before taking CEFTIZOXIME+SULBACTAM.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
not applicableAvoid consuming alcohol while taking CEFTIZOXIME+SULBACTAM.
Pregnancy
cautionCEFTIZOXIME+SULBACTAM should only be given during pregnancy when the need has been established. Therefore, please inform your doctor if you are pregnant or planning for pregnancy; your doctor will weigh the benefits and potential risks before prescribing this medicine.
Breast Feeding
cautionInform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, taking into account the importance of the medicine to the mother.
Driving
safe if prescribedCEFTIZOXIME+SULBACTAM is unlikely to affect your ability to drive.
Liver
cautionCaution should be exercised while using CEFTIZOXIME+SULBACTAM in patients with liver disease. Inform your doctor before receiving CEFTIZOXIME+SULBACTAM if you have a history of liver diseases. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionCaution should be exercised while using CEFTIZOXIME+SULBACTAM in patients with kidney disease. Inform your doctor before receiving CEFTIZOXIME+SULBACTAM if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.
Children
cautionLimited information is available for the use of CEFTIZOXIME+SULBACTAM in children. Hence, it will be administered to the children only if needed.
Habit Forming
Diet & Lifestyle Advise
- Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
- Avoid intake of alcoholic beverages with CEFTIZOXIME+SULBACTAM as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid CEFTIZOXIME+SULBACTAM in fighting off infections.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is when harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
FAQs
CEFTIZOXIME+SULBACTAM is used to treat Bacterial infections.
CEFTIZOXIME+SULBACTAM contains Ceftizoxime and Sulbactam. Ceftizoxime works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby killing the bacteria. Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, CEFTIZOXIME+SULBACTAM helps to treat bacterial infections.
CEFTIZOXIME+SULBACTAM may cause Clostridium difficile-associated diarrhoea (CDAD). Antibiotic treatment alters the normal flora, leading to overgrowth of Clostridium difficile, which causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking CEFTIZOXIME+SULBACTAM and consult your doctor. Do not take anti-diarrheal medicine on your own.
Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor.
Usually, CEFTIZOXIME+SULBACTAM starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.
To reduce the development of antibiotic resistance and maintain the effectiveness of CEFTIZOXIME+SULBACTAM, it should only be used to treat or prevent infections that are proven or highly suspected to be caused by bacteria.
