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Cefpodoxime+clavulanic Acid

About Cefpodoxime+clavulanic Acid

Cefpodoxime+clavulanic Acid is used to treat various bacterial infections such as pharyngitis/tonsillitis (throat infections), otitis media (ear infections), sinusitis (infection of the sinuses), community-acquired pneumonia, gonorrhoea (sexually transmitted disease), anorectal infections in women, skin, and urinary tract infections. 

Cefpodoxime+clavulanic Acid contains Cefpodoxime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor). Cefpodoxime works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thus, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of Cefpodoxime against the bacteria. Together, Cefpodoxime+clavulanic Acid helps to treat bacterial infections.

Take Cefpodoxime+clavulanic Acid with food. The dose and duration of Cefpodoxime+clavulanic Acid can vary depending on your condition and the severity of the infection. In some cases, you may experience certain common side effects, such as diarrhoea, abdominal pain, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before starting Cefpodoxime+clavulanic Acid, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take $ your name on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Cefpodoxime+clavulanic Acid if you are pregnant or planning for pregnancy. Avoid taking Cefpodoxime+clavulanic Acid if you are breastfeeding as Cefpodoxime+clavulanic Acid may pass into breast milk. Avoid alcohol consumption while taking Cefpodoxime+clavulanic Acid to prevent unpleasant side effects. Cefpodoxime+clavulanic Acid may cause dizziness, so drive with caution.

Uses of Cefpodoxime+clavulanic Acid

Treatment of Bacterial infections.

Medicinal Benefits

Cefpodoxime+clavulanic Acid belongs to the group of medicines called antibiotics used to treat various bacterial infections such as pharyngitis/tonsillitis (throat infections), otitis media (ear infections), sinusitis (infection of the sinuses), community-acquired pneumonia, gonorrhoea (sexually transmitted disease), anorectal infections in women, skin, and urinary tract infections. Cefpodoxime+clavulanic Acid is a combination of two antibiotics: Cefpodoxime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor). Cefpodoxime works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thus, it kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of cefpodoxime against the bacteria. Together, Cefpodoxime+clavulanic Acid helps to treat bacterial infections. Cefpodoxime+clavulanic Acid is a broad-spectrum antibiotic which is effective against both gram-positive and gram-negative bacteria, including beta-lactamase-producing strains.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule. Dispersible tablet: Disperse the tablet in water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cefpodoxime+clavulanic Acid

  • Diarrhoea
  • Abdominal pain
  • Nausea
  • Vomiting

Drug Warnings

Before starting Cefpodoxime+clavulanic Acid, please inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Cefpodoxime+clavulanic Acid should not be given to patients with rare hereditary problems of galactose intolerance (the Lapp lactase deficiency or glucose-galactose malabsorption). Do not take Cefpodoxime+clavulanic Acid on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking Cefpodoxime+clavulanic Acid if you have colitis (inflammation of the colon).  Consult your doctor before taking Cefpodoxime+clavulanic Acid if you are pregnant or planning for pregnancy. Avoid taking Cefpodoxime+clavulanic Acid if you are breastfeeding as it may pass into breast milk. Avoid alcohol consumption while taking Cefpodoxime+clavulanic Acid to prevent unpleasant side-effects. Cefpodoxime+clavulanic Acid causes dizziness, so drive with caution.

Drug Interactions

Drug-Drug Interactions: Cefpodoxime+clavulanic Acid may have interaction with anticoagulants (warfarin), anti-gout (probenecid), diuretics (furosemide), and vitamin supplements (calcium/vitamin D).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you have colitis (inflammation in the lining of the colon), seizures, dialysis, kidney and liver dysfunction.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • PROBENECID
  • FUROSEMIDE
  • CALCIUM CARBONATE+CHOLECALCIFEROL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consuming alcohol while taking Cefpodoxime+clavulanic Acid to prevent unpleasant side-effects.

    • Safety Warning

      Pregnancy

      caution

      Cefpodoxime+clavulanic Acid belongs to pregnancy category B. Please consult your doctor if you are pregnant, your doctor will prescribe Cefpodoxime+clavulanic Acid only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Cefpodoxime+clavulanic Acid may pass into breast milk. Avoid taking Cefpodoxime+clavulanic Acid if you are breastfeeding unless prescribed.

    • Safety Warning

      Driving

      caution

      Cefpodoxime+clavulanic Acid may cause dizziness. Drive only if you are alert and omit driving or operating machinery if you feel dizzy.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Please consult your doctor before taking Cefpodoxime+clavulanic Acid if you have liver impairment/liver disease.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Cefpodoxime+clavulanic Acid.

    • Safety Warning

      Children

      safe if prescribed

      Cefpodoxime+clavulanic Acid is safe for children if prescribed by a doctor. The dose and duration may vary depending upon age and severity of the infection.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat fibre rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

    • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

    • Avoid consumption of alcohol and usage of tobacco.

    • Antibiotics can alter the useful bacteria in the stomach, which help indigestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

    Patients Concern

    Disease/Condition Glossary

    Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue. Bacteria are of various forms, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.

    FAQs

    Cefpodoxime+clavulanic Acid is used to treat various bacterial infections such as pharyngitis/tonsillitis (throat infections), otitis media (ear infections), sinusitis (infection of the sinuses), community-acquired pneumonia, gonorrhoea (sexually transmitted disease), anorectal infections in women, skin, and urinary tract infections.

    Cefpodoxime+clavulanic Acid is a combination of two antibiotics, namely: Cefpodoxime (cephalosporin antibiotic) and Clavulanic acid (beta-lactamase inhibitor). Cefpodoxime works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby, kills the bacteria. Clavulanic acid works by decreasing bacterial resistance and enhancing the activity of cefpodoxime against the bacteria. Together, Cefpodoxime+clavulanic Acid helps to treat bacterial infections.

    Cefpodoxime+clavulanic Acid may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Cefpodoxime+clavulanic Acid and consult your doctor. Do not take anti-diarrheal medicine on your own.

    Do not stop taking Cefpodoxime+clavulanic Acid despite symptomatic relief. To treat your condition effectually continue taking Cefpodoxime+clavulanic Acid for as long as it has been prescribed for you.

    Do not take Cefpodoxime+clavulanic Acid on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

    Cefpodoxime+clavulanic Acid usually begins to work soon after taking it. However, it may take few days to kill all the harmful bacteria and make you feel better.

    If you don't feel better after completing the full course of treatment with Cefpodoxime+clavulanic Acid, inform your doctor. Also, let your doctor know if your symptoms are worsening while taking Cefpodoxime+clavulanic Acid.

    Cefpodoxime+clavulanic Acid may cause serious side effects in very few patients (less than 1 in 1,000). If you get bloody diarrhea, bruising or skin discoloration, yellowing of the eyes and skin, skin peeling, shortness of breath, widespread rash, and fever, inform your doctor immediately.

    Yes, Cefpodoxime+clavulanic Acid can cause allergic reaction and is harmful to patients with known allergy to a class of antibiotics called Cephalosporins. If you notice any of the signs of an allergic reaction such as difficulty in breathing; hives; swelling of your face, tongue, lips, or throat, contact your doctor immediately.

    The use of Cefpodoxime+clavulanic Acid is contraindicated in patients with known allergy to Penicillins or any other excipients in Cefpodoxime+clavulanic Acid. It should also be avoided by patients with previous history of liver damage associated with Cefpodoxime+clavulanic Acid.

    No, you are recommended not to take oral contraceptive pills while taking Cefpodoxime+clavulanic Acid as it may reduce the effectiveness of birth control pills. Therefore, discuss with your doctor about using a birth control method which does not affect your hormone levels (such as a diaphragm, condom, and spermicide).

    No, do not take higher than the recommended dose of Cefpodoxime+clavulanic Acid as it may increase the risks of side effects. If your symptoms worsen, while taking Cefpodoxime+clavulanic Acid, please consult the doctor.

    Store Cefpodoxime+clavulanic Acid at room temperature. Protect from light and moisture. Keep it out of reach of children.

    Please consult your doctor if you are pregnant. Your doctor will prescribe Cefpodoxime+clavulanic Acid only if the benefits are greater than the risks.

    You are recommended to avoid alcohol consumption while taking Cefpodoxime+clavulanic Acid as it may increase the risk of side effects.

    If you miss a dose of Cefpodoxime+clavulanic Acid, do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.

    Available Medicines for

    Cefpodoxime+clavulanic Acid

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