Azelnidipine+chlorthalidone
About Azelnidipine+chlorthalidone
Azelnidipine+chlorthalidone is used to treat high blood pressure and oedema (fluid build-up in the body). It reduces the risk of fatal and non-fatal cardiovascular diseases. High blood pressure, or hypertension, is a chronic condition where the force of blood against artery walls is excessively high, leading to complications such as heart disease, irregular heartbeat, and oedema. As an antihypertensive drug, Azelnidipine+chlorthalidone plays a crucial role in managing hypertension, a lifelong condition characterized by elevated blood pressure, which can overwork the heart and lead to severe health issues.
The Azelnidipine+chlorthalidone contains Azelnidipine and chlorthalidone. Azelnidipine relaxes blood vessels to lower blood pressure and reduce the risk of heart attack and stroke. Chlorthalidone, a diuretic, increases urine production to remove excess fluids and treat hypertension and oedema.
Take Azelnidipine+chlorthalidone as prescribed by your doctor. You are advised to take Azelnidipine+chlorthalidone for as long as your doctor has prescribed it based on your medical condition. Sometimes, you may experience dizziness, muscle cramps, thirst, stomach pain, upset stomach, vomiting, diarrhoea, loss of appetite, and headache. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Do not stop taking this medicine without completing the prescribed dose, as abruptly stopping it may cause a rise in blood pressure and can increase the risk of getting heart disease and stroke. Inform your doctor about any pre-existing kidney, liver, or heart conditions, as well as pregnancy, breastfeeding, or other medications, to ensure safe usage.
Uses of Azelnidipine+chlorthalidone
Medicinal Benefits
Azelnidipine+chlorthalidone is used to treat high blood pressure, heart failure, and fluid build-up. It contains chlorthalidone and azelnidipine, which work together to increase urine production and relax blood vessels, reducing heart workload and improving blood flow. This helps lower blood pressure, reduces heart attack and stroke risk, and treats hypertension and fluid build-up.
Directions for Use
Take Azelnidipine+chlorthalidone as advised by the doctor. Swallow Azelnidipine+chlorthalidone as a whole with a glass of water. Do not crush, break, or chew it.
Storage
Side Effects of Azelnidipine+chlorthalidone
- Muscle cramps
- Vomiting
- Headache
- Thirst
- Dizziness
- Diarrhea
- Stomach upset
- Loss of appetite
- Stomach pain
Drug Warnings
If you are allergic to Azelnidipine+chlorthalidone or any of its components or taking other medications, including supplements, please tell your doctor. Do not stop taking Azelnidipine+chlorthalidone without a doctor's advice. Sudden stopping of Azelnidipine+chlorthalidone may cause changes in your blood pressure. Consult your doctor before using Azelnidipine+chlorthalidone if you are pregnant or breastfeeding. Inform your doctor if you have any kidney, liver, or gout (high uric acid) disease, high cholesterol (hyperlipidemia) disease, or any pre-existing medical conditions.
Drug Interactions
Drug-Drug Interaction: Azelnidipine+chlorthalidone may interact with xanthine oxidase inhibitors (allopurinol), photosensitizing inhibitors (aminolevulinic acid), antiarrhythmic drugs (amiodarone), dopamine agonists (apomorphine), anti-neoplastic agents (arsenic trioxide), prokinetic agents (cisapride), antipsychotic agents (pimozide sodium nitrite, ziprasidone), skeletal muscle relaxants (tizanidine), anti-manic agents (lithium), and narcotic analgesic agents (levomethadyl acetate).
Drug-Food Interaction: Azelnidipine+chlorthalidone can interact with alcohol, causing your blood pressure to drop too low.
Drug-Disease Interaction: Inform your doctor before taking Azelnidipine+chlorthalidone if you have kidney, liver, or heart problems, anuria, or lupus erythematosus.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAzelnidipine+chlorthalidone may interact with alcohol, as it may cause your blood pressure to drop too low.
Pregnancy
cautionPlease consult a doctor if you are pregnant. Azelnidipine+chlorthalidone is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether Azelnidipine+chlorthalidone is excreted in human milk. However, if the doctor thinks the benefits outweigh the risks, Azelnidipine+chlorthalidone is given to breastfeeding mothers.
Driving
cautionDrive only if you are alert after taking Azelnidipine+chlorthalidone, as it may cause dizziness in some people.
Liver
cautionTake Azelnidipine+chlorthalidone with caution if you have a history of liver disease. Your doctor may adjust the dose depending on your current liver condition.
Kidney
cautionTake Azelnidipine+chlorthalidone with caution if you have a history of kidney disease. Your doctor may adjust the dose based on your current kidney condition.
Children
consult your doctorSafety and effectiveness in children have not been established. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Eat a balanced diet with fruits, vegetables, whole grains, and lean proteins.
- Control your weight (BMI: 19.5-24.9).
- Limit salt intake (<2,300 mg/day).
- Avoid refined foods, trans fatty acids, and excessive alcohol.
- Use healthy cooking oils.
- Manage stress with mindfulness and loved ones.
- Exercise regularly (e.g., walking).
- Quit smoking and limit alcohol consumption.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition where blood pressure is too high, increasing the risk of heart attack, stroke, and kidney failure. Ideal blood pressure ranges from 90/60 to 120/80mmHg.
Oedema: It is also known as fluid retention, causing swelling in the body's tissues, often due to prolonged standing, salty foods, or being overweight.
FAQs
Azelnidipine+chlorthalidone is used to treat high blood pressure (hypertension) and oedema (a build-up of fluid in the body).
Azelnidipine+chlorthalidone works by increasing urine production and relaxing blood vessels, reducing heart workload and improving blood flow. This helps in lowering blood pressure, reducing heart attack and stroke risk, and treating hypertension and fluid build-up.
Taking Azelnidipine+chlorthalidone may cause dehydration. So, to avoid dehydration, drink plenty of water and inform your doctor if you feel extremely thirsty.
Unlikely that Azelnidipine+chlorthalidone affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There is not enough evidence to say for certain. For the best advice, consult your doctor.
Azelnidipine+chlorthalidone can be safely taken as long as your doctor prescribes it. High blood pressure is life-long and should not be abruptly discontinued without discussing it with a doctor. Consult your doctor if you have concerns regarding it.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Take Azelnidipine+chlorthalidone as prescribed by the doctor. It can be taken daily if the doctor advises it.
It is not recommended to consume alcohol with Azelnidipine+chlorthalidone as it may interact, causing your blood pressure to drop too low.
Avoid exceeding the recommended dose and take Azelnidipine+chlorthalidone as advised by the doctor. Taking more than the recommended dose of Azelnidipine+chlorthalidone may cause an overdose. The symptoms of an overdose of Azelnidipine+chlorthalidone may include drowsiness, dizziness, nausea, extreme thirst, or rapid heartbeats. If you suspect you have taken an overdose or notice signs of overdose, please consult the doctor immediately.
The common side effects of Azelnidipine+chlorthalidone may include dizziness, muscle cramps, thirst, stomach pain, upset stomach, vomiting, diarrhoea, loss of appetite, and headache. Most of these side effects of Azelnidipine+chlorthalidone do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
