Acebrophylline+acetylcysteine
About Acebrophylline+acetylcysteine
Acebrophylline+acetylcysteine belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner) primarily used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).
Acebrophylline+acetylcysteine is a combination of two drugs: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner). Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Acebrophylline+acetylcysteine breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
Take Acebrophylline+acetylcysteine as prescribed. Your doctor will recommend how often you take Acebrophylline+acetylcysteine based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. Most of these side effects of Acebrophylline+acetylcysteine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Acebrophylline+acetylcysteine or any other medicines, please tell your doctor. Acebrophylline+acetylcysteine is not recommended for children below 14 years of age. Drink plenty of fluids to thin mucus and lubricate your throat while taking Acebrophylline+acetylcysteine. Acebrophylline+acetylcysteine is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Acebrophylline+acetylcysteine. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Acebrophylline+acetylcysteine and contact your doctor immediately. Do not take Acebrophylline+acetylcysteine if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Acebrophylline+acetylcysteine if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Acebrophylline+acetylcysteine.
Uses of Acebrophylline+acetylcysteine
Medicinal Benefits
Acebrophylline+acetylcysteine is a combination of two drugs: Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Acebrophylline+acetylcysteine breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
Directions for Use
Storage
Side Effects of Acebrophylline+acetylcysteine
- Diarrhoea
- Stomach pain
- Nausea
- Vomiting
- Runny nose
- Dizziness
- Drowsiness
- Heartburn
- Skin rash
- Hives
- Itching
- Cool and moist skin
Drug Warnings
If you are allergic to Acebrophylline+acetylcysteine or any other medicines, please tell your doctor. Acebrophylline+acetylcysteine is not recommended for children below 14 years of age. Regular monitoring of potassium levels is recommended while taking Acebrophylline+acetylcysteine as it may cause low potassium levels in the blood. Acebrophylline+acetylcysteine is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Acebrophylline+acetylcysteine. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Acebrophylline+acetylcysteine and contact your doctor immediately. Do not take Acebrophylline+acetylcysteine if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Acebrophylline+acetylcysteine if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Acebrophylline+acetylcysteine.
Drug Interactions
Drug-Drug Interaction: Acebrophylline+acetylcysteine may interact with water pills (furosemide), medicines used to treat gout (allopurinol), antacid (cimetidine), antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, tetracycline, gentamicin, amikacin, neomycin), drugs used to lower high blood pressure (diltiazem, verapamil), heart-related medicines (isoprenaline), anthelmintic (thiabendazole), corticosteroids (prednisone), oral contraceptives (ethinylestradiol), medicines used to treat chest pain (glyceryl trinitrate) and cough suppressants (dextromethorphan, codeine).
Drug-Food Interaction: If you are allergic to histamine, avoid histamine-rich foods such as tomatoes, wine, and processed foods. These may cause histamine intolerance, leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching, and rhinitis (runny and stuffy nose). Also, avoid alcohol with Acebrophylline+acetylcysteine as it may increase drowsiness. Also, avoid or limit the intake of caffeine with Acebrophylline+acetylcysteine as it may cause side effects.
Drug-Disease Interaction: Avoid taking Acebrophylline+acetylcysteine if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Acebrophylline+acetylcysteine.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Acebrophylline+acetylcysteine as it may reduce the effectiveness of Acebrophylline+acetylcysteine and increase drowsiness. Please consult a doctor before consuming alcohol with Acebrophylline+acetylcysteine.
Pregnancy
unsafeAcebrophylline+acetylcysteine is not recommended for pregnant women. Please consult a doctor before using Acebrophylline+acetylcysteine if you are pregnant.
Breast Feeding
cautionIt is unknown whether Acebrophylline+acetylcysteine is excreted in human milk. Please consult a doctor before taking Acebrophylline+acetylcysteine if you are breastfeeding.
Driving
safe if prescribedAcebrophylline+acetylcysteine usually does not affect your ability to drive or operate machinery.
Liver
cautionTake Acebrophylline+acetylcysteine with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose as required.
Kidney
cautionTake Acebrophylline+acetylcysteine with caution, especially if you have a history of Kidney diseases or conditions. Your doctor may adjust the dose as needed.
Children
cautionAcebrophylline+acetylcysteine is not recommended for children below 14 years of age. Please consult a doctor before giving Acebrophylline+acetylcysteine to children.
Habit Forming
Diet & Lifestyle Advise
- Eat foods rich in potassium, such as bananas, asparagus, oranges, potatoes, avocados, dark leafy greens, and beetroots. Potassium is important for lung function, and a potassium deficiency may cause breathing problems.
- Drink plenty of fluids every day to thin mucus, which makes it easier for coughing out.
- Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas and potatoes with skin.
- Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like Red Bull.
- Eat protein-rich foods such as meat, fish (particularly salmon, sardines and mackerel), eggs and poultry.
- Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
- Quit smoking as it may reduce the effectiveness of the Acebrophylline+acetylcysteine and irritate the lungs, worsening breathing problems.
Special Advise
- Regular blood tests are recommended while taking Acebrophylline+acetylcysteine to monitor the levels of Acebrophylline+acetylcysteine and potassium in the blood.
- Acebrophylline+acetylcysteine may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Acebrophylline+acetylcysteine before undergoing any laboratory tests.
Patients Concern
Disease/Condition Glossary
Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).
FAQs
Acebrophylline+acetylcysteine is used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD), such as shortness of breath, coughing, or wheezing (whistling sound while breathing).
Acebrophylline+acetylcysteine contains Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Acebrophylline+acetylcysteine breakdown the acid mucopolysaccharide fibres that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.
Acebrophylline+acetylcysteine should be used with caution in patients suffering from epilepsy (fits) as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Acebrophylline+acetylcysteine so that the dose may be adjusted or an alternate medicine may be prescribed.
It is not recommended to take Acebrophylline+acetylcysteine with antibiotics such as tetracycline, amoxicillin, amikacin, and gentamicin at the same time, as this may reduce the effectiveness of the antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of at least 2 hours between taking Acebrophylline+acetylcysteine and antibiotics. Please consult a doctor before using Acebrophylline+acetylcysteine with antibiotics or any other medicines.
It is recommended that you avoid taking Acebrophylline+acetylcysteine if you are allergic to acebrophylline, ambroxol, or theophylline, suffer from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders, or have had a heart attack. However, inform your doctor if you have any of these conditions before taking Acebrophylline+acetylcysteine.
No, you are not recommended to smoke while taking Acebrophylline+acetylcysteine as it may reduce the effectiveness of Acebrophylline+acetylcysteine and also damage your lungs. Long-term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.
You are recommended to avoid histamine-rich foods such as tomatoes, wine, and processed foods. These may cause histamine intolerance by affecting the way histamine is broken down in the body, leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching, and rhinitis (runny and stuffy nose). Therefore, if you are allergic to histamine or cannot tolerate food and drinks rich in histamine, please inform your doctor before taking Acebrophylline+acetylcysteine.
No, you are not recommended to stop taking Acebrophylline+acetylcysteine without consulting your doctor. Doing so may worsen your cough and other breathing problems, causing recurring symptoms. Therefore, take Acebrophylline+acetylcysteine for as long as your doctor has prescribed it, and if you experience any difficulty while taking it, please consult your doctor.
No, Acebrophylline+acetylcysteine does not relieve sudden asthma symptoms. Therefore, it is advised to always carry a rescue inhaler to treat sudden asthma symptoms.
No, Acebrophylline+acetylcysteine is not an antibiotic. It is a combination of two drugs: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner).
Acebrophylline+acetylcysteine may cause side effects like diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. If the side effects persist or worsen, please consult your doctor.
Acebrophylline+acetylcysteine may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Acebrophylline+acetylcysteine before undergoing any laboratory tests.
Not only will taking higher doses of Acebrophylline+acetylcysteine not be more effective, but it can also cause side effects. It is important to avoid exceeding the recommended dose.
Store Acebrophylline+acetylcysteine at room temperature, in a dry place. Keep out of sight and reach of children.
No, do not take Acebrophylline+acetylcysteine if you are allergic to any of its components. Let the doctor know if you are allergic to Acebrophylline+acetylcysteine; the doctor will prescribe alternate medicines.
If you miss a dose of Acebrophylline+acetylcysteine take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
