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compositionComposition:DICLOFENAC-100MG
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Prescription Medicine
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Jonac Suppositories is used to relieve pain and inflammation. It contains Diclofenac, which works by blocking the chemical messengers that cause pain and swelling. In some cases, this medicine may cause side effects like nausea, vomiting, diarrhoea, heartburn and stomach pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-100MG

Manufacturer/Marketer :

German Remedies Ltd

Consume Type :

Rectal

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Jonac Suppositories

Jonac Suppositories is used to relieve pain and inflammation in conditions affecting joints, tendons, and muscles. They are also used to treat juvenile chronic arthritis and post-operative pain in children.

Jonac Suppositories contains Diclofenac, which works by inhibiting the synthesis of certain chemical messengers responsible for causing pain and inflammation. Thus, Jonac Suppositories helps provide relief from pain.

In some cases, Jonac Suppositories may cause common side effects such as stomach pain, nausea, vomiting, heartburn, and diarrhoea. Most of these side effects may not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Do not use Jonac Suppositories if you are allergic to any of its components. Jonac Suppositories should not be taken by mouth; it is for rectal use only. Consult your doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Jonac Suppositories

Jonac Suppositories is used in the treatment of pain and inflammation. The detailed uses of Jonac Suppositories are as follows:

  • Relieve pain and inflammation: Jonac Suppositories is used for this purpose.
  • Post-Surgical Pain Relief: Jonac Suppositories is used after surgeries to reduce pain and swelling.
  • Arthritis Treatment: Jonac Suppositories helps manage pain in conditions like rheumatoid arthritis and osteoarthritis.
  • Gout Attacks: Jonac Suppositories provides relief from acute gout-related inflammation.
  • Muscle and Joint Injuries: Jonac Suppositories is used for sprains, strains, and sports injuries.

Key Benefits

  • Jonac Suppositories belongs to a group of medicines called Non-Steroidal Anti-Inflammatory Drugs (NSAIDs).
  • It is used to relieve pain, ease inflammation, and reduce swelling in conditions affecting the joints, tendons and muscles such as rheumatoid arthritis, osteoarthritis, acute gout, ankylosing spondylitis, backache, sprains, strains, soft tissue sports injuries, frozen shoulder, dislocations, fractures, tendonitis, tenosynovitis, and bursitis.
  • It is also used to treat pain and inflammation associated with dental and minor surgery.
  • Additionally, diclofenac is used to treat juvenile chronic arthritis in children aged 1 to 12 years and post-operative pain in children above 6 years.
  • Jonac Suppositories contains Diclofenac, which works by blocking the effect of cyclooxygenase (COX) enzymes. This inhibits prostaglandin synthesis and thereby relieves pain and inflammation.
Side effects of Jonac Suppositories
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Check the label for directions before using Jonac Suppositories.
  • Empty your bowels before inserting the suppository. Lie on one side with your knees pulled up towards your chest. Remove the wrapper and insert the pointed end of the suppository into the rectum. Push the suppository as far as possible.
  • Wash your hands thoroughly before and after use.
  • Try not to empty your bowels for at least an hour after using Jonac Suppositories.

How Jonac Suppositories Works

Jonac Suppositories contains Diclofenac, which works by inhibiting the synthesis of certain chemical messengers responsible for causing pain and inflammation. Thus, Jonac Suppositories helps provide relief from pain.
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Alcohol

Unsafe

Avoid consumption of alcohol as it may increase the risk of gastrointestinal side effects.

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Pregnancy

Consult your doctor

Diclofenac should be used during the first 6 months of pregnancy only if necessary and advised by your doctor. It is not recommended for use in the last 3 months of pregnancy as it may harm the unborn child or cause problems at delivery. Hence, if you are pregnant or planning pregnancy, consult your doctor before starting Jonac Suppositories.

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Breast Feeding

Consult your doctor

Please consult the doctor if you are breastfeeding. Diclofenac should be avoided during lactation as it may pass into breast milk and cause undesirable effects in the infant.

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Driving

Caution

Occasionally, Jonac Suppositories may cause dizziness. Drive or operate machinery only if you are alert.

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Liver

Consult your doctor

Jonac Suppositories is not recommended if you have liver failure. Please consult the doctor if you have liver problems.

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Kidney

Consult your doctor

Jonac Suppositories is not recommended if you have kidney failure. Please consult the doctor if you have kidney problems.

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Children

Unsafe

Please consult the doctor. The doctor will determine the appropriate dose for use in children.

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Heart

Caution

Please inform your doctor if you have heart problems before using Jonac Suppositories, as it is contraindicated in patients with conditions like ischemic heart disease, stroke history, or congestive heart failure.

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Geriatrics

Consult your doctor

Please inform your doctor if you are geriatric before using Jonac Suppositories, as older adults are more prone to side effects like gastrointestinal bleeding and cardiovascular risks. Medical supervision is essential to ensure the lowest effective dose and safe use.

What if I have taken an overdose of Jonac Suppositories

Taking more than your prescribed dose of Jonac Suppositories can be dangerous. It can cause side effects such as stomachache, feeling sick, or vomiting. If you encounter these symptoms or think you might have taken too much, get medical help right away.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Stay hydrated, drink plenty of water.
  • Manage stress by doing meditation or yoga.
health query

Have a query?

How Soon It Starts Working

  • The time required for Jonac Suppositories to start to work: Jonac Suppositories ideally shows its action within 1 hour after administration. 
  • The time for which the effects of Jonac Suppositories last: The effect of Jonac Suppositories lasts for 8 hours.

What if you forget to take Jonac Suppositories

If you miss a dose of Jonac Suppositories, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and continue back to your regular dosage routine. Avoid taking two doses at once. Consult your healthcare provider if unsure.

Storage

• Store in a cool and dry place away from sunlight.• Keep Jonac Suppositories out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not use Jonac Suppositories if you are allergic to any of its components.
  • Also, avoid taking Jonac Suppositories if you have/had a gastric/peptic ulcer, stomach/bowel problems after taking other NSAIDs, heart, kidney or liver failure, heart attack, stroke, blockage of blood vessels to the heart or brain, bypass surgery, or blood circulation problems.
  • Inform the doctor if you have/had ulcerative colitis or Crohn’s disease, liver or kidney problems, porphyria, bleeding disorder, asthma, high blood pressure, angina, diabetes, high cholesterol, or lupus.
  • Jonac Suppositories should be used during the first 6 months of pregnancy only if necessary and advised by your doctor.
  • It is not recommended for use in the last 3 months of pregnancy and in breastfeeding women.
  • Let the doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform the doctor if you are taking anti-diabetics, blood thinners (warfarin), diuretics, anti-manic agents (lithium), antimetabolites (methotrexate), immunosuppressants (ciclosporin, tacrolimus), antibiotics (trimethoprim), a medicine used to terminate a pregnancy (mifepristone), cardiac glycosides (digoxin), oral steroids, anti-fungal (voriconazole), anti-convulsant (phenytoin), a drug used to lower cholesterol (cholestyramine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have/had stomach ulcers or perforation, bleeding problems, heart attack, stroke, blood circulation problems, bowel disorders, or asthma.

DiclofenacMeloxicam
Critical
DiclofenacAmiloride
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Jonac Suppositories is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacAmiloride
Severe
How does the drug interact with Jonac Suppositories:
Taking amiloride with Jonac Suppositories can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Jonac Suppositories and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacFlurbiprofen
Severe
How does the drug interact with Jonac Suppositories:
Co-administration use of Jonac Suppositories with Flubiprofen may increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
There is a possibility of interaction between Jonac Suppositories and Flubiprofen but they can be taken together if your doctor has prescribed them. Consult your doctor immediately if you experience any symptoms like Nausea, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, burning in stomach, acidity, severe headache and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacPonatinib
Severe
How does the drug interact with Jonac Suppositories:
Taking Jonac Suppositories with Ponatinib can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and Ponatinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacIbuprofen
Severe
How does the drug interact with Jonac Suppositories:
Taking Jonac Suppositories and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Jonac Suppositories and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacTacrolimus
Severe
How does the drug interact with Jonac Suppositories:
Co-administration of Jonac Suppositories with tacrolimus may cause kidney problems.

How to manage the interaction:
Co-administration of Jonac Suppositories and Tacrolimus can lead to an interaction, it can be taken if advised by your doctor. However, consult your doctor if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without a doctor's advice.
DiclofenacMethotrexate
Severe
How does the drug interact with Jonac Suppositories:
Co-administration of methotrexate with Jonac Suppositories can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Jonac Suppositories, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacLeflunomide
Severe
How does the drug interact with Jonac Suppositories:
Co administration of Jonac Suppositories with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Jonac Suppositories and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.
DiclofenacValdecoxib
Severe
How does the drug interact with Jonac Suppositories:
Taking Valdecoxib with Jonac Suppositories may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Jonac Suppositories and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[NON-STEROIDAL DRUG, ANTI- INFLAMMATORY AGENTS]

FAQs

Jonac Suppositories is used to relieve pain and inflammation in conditions affecting joints, tendons and muscles.
Jonac Suppositories works by inhibiting the synthesis of certain chemical messengers that cause pain and inflammation. Thereby, Jonac Suppositories helps provide relief from pain.
Jonac Suppositories might make it more difficult to conceive. Please consult the doctor if you have concerns regarding this.
It is advised to use the lowest effective dose for the shortest durations. However, use Jonac Suppositories for as long as it has been recommended by the doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.1044 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.5750 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Voltarol Suppositories 12 5Mg Leaflet Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Diclofenac Diclofenac. 1998. [Accessed on 02 Apr. 2019]Check here
  5. Diclofenac sodium [Prescribing Information]. 2021. [Accessed on 06 Apr. 2024]Check here
  6. Cipla Limited. REACTIN® 100 SR Tablets – Product Information [Internet]. Mumbai: Cipla Limited; [Accessed on 2025 Sep 17]Check here
  7. Dexcel Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 29th July 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads, Ahmedabad – 380015, Gujarat, India.
Other Info - JON0011

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