ZONALTA 8 TABLETS is used to treat or reduce the symptoms of manic episodes in bipolar I illness, with or without mixed characteristics (both highs and lows at the same time). Manic depression is another term for bipolar illness, a serious brain disorder characterized by significant mood swings (thinking variations) and frequent mood and behaviour changes.

ZONALTA 8 TABLETS contains 'Endoxifen,' which works in the nervous system by inhibiting protein kinase C activity (which is elevated in patients with bipolar I illness during their manic phase) and thus helps to manage certain chemicals in the brain that control your moods, such as serotonin, norepinephrine, and dopamine.

Take ZONALTA 8 TABLETS as your doctor or healthcare professional has suggested it. In some cases, you may experience certain common side effects such as headache, vomiting, Inability to sleep, sleeping more than usual, abdominal discomfort, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not use ZONALTA 8 TABLETS without a doctor's advice if you have a skin reaction or irritation to any medicine. Do not stop taking ZONALTA 8 TABLETS without consulting your doctor to avoid worsening your condition. To treat your condition effectually, continue taking ZONALTA 8 TABLETS for as long as your doctor has suggested, even if you feel better. Do not take ZONALTA 8 TABLETS if you are pregnant or breastfeeding. ZONALTA 8 TABLETS causes sleepiness and restlessness; do not drive unless alert. ZONALTA 8 TABLETS should not be given to children as safety and effectiveness have not been established. Consuming alcohol with ZONALTA 8 TABLETS may cause drowsiness and dizziness. Keep your healthcare professional informed about your medical condition and your medications to rule out any potential negative effects and interactions.

ZONALTA 8 TABLETS contains 'Endoxifen,' which works in the nervous system by inhibiting protein kinase C activity (which is increased in patients with bipolar I disorder during the manic phase) and thus helps to manage certain chemicals in the brain that control your moods, such as serotonin, norepinephrine, and dopamine. It Improves overall manic symptoms with or without mixed characteristics (both highs and lows at the same time). Altogether it effectively reduces the overall severity of the illness.

• Headache
• Vomiting
• Inability to sleep or insomnia
• Somnolence or sleeping more than usual
• Gastritis or stomach upset
• Upper abdominal discomfort
• Diarrhoea
• Restlessness

Please do not use ZONALTA 8 TABLETS without doctor advice if you have a skin reaction or are sensitive to any medicine. Do not stop taking ZONALTA 8 TABLETS without consulting your doctor to avoid worsening your condition. To treat your condition effectually, continue taking ZONALTA 8 TABLETS for as long as your doctor has suggested, even if you feel better. Do not take ZONALTA 8 TABLETS if you are pregnant or breastfeeding. It is recommended to use effective contraceptive methods while using ZONALTA 8 TABLETS. ZONALTA 8 TABLETS causes sleepiness and restlessness; do not drive unless alert. ZONALTA 8 TABLETS should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol and ZONALTA 8 TABLETS as it could lead to undesirable effects. Keep your doctor updated on your medical condition and medications to rule out any potential side effects.

Drug-Drug Interactions: ZONALTA 8 TABLETS may interact with coumarin derivative medications (e.g. phenprocoumon, warfarin, acenocoumarol) and cytochrome p450 inducer medications (e.g. omeprazole, Lansoprazole).

Food-Drug Interactions: Limit or avoid the consumption of alcohol.

Drug-Disease Interactions: ZONALTA 8 TABLETS may have interactions with hepatic or renal dysfunction, ocular disturbances, and blood clotting disorders.

• PHENPROCOUMON
• WARFARIN
• ACENOCOUMAROL
• OMEPRAZOLE
• LANSOPRAZOLE

• Lifestyle adjustments and mood-management techniques can be beneficial.

• Always maintain a healthy diet and exercise regularly.

• Attend counselling regularly.

• Practice meditation and yoga.

• Maintain a consistent sleep schedule.

• Avoid smoking and drinking alcohol.

Before beginning therapy, it is suggested that a pregnancy test be performed. All patients are instructed to use effective contraception while undergoing treatment.

Bipolar disorder: It is also known as manic depression or bipolar disease, a mental health disorder associated with mood swings episodes ranging from manic highs to depressive lows.