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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Zexcy A 400mg/30mg Tablet is used to treat cough associated with respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). It contains Doxofylline and Ambroxol which work by relaxing and widening the muscles of the airways, making it easier to breathe. In some cases, this medicine may cause side effects such as nausea, taste change, stomach pain, photosensitivity, and numbness in the mouth, tongue, and throat. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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About Zexcy A 400mg/30mg Tablet

Zexcy A 400mg/30mg Tablet is a respiratory combination medication primarily used to treat cough associated with respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). Asthma is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of your bronchial tubes). Cough occurs as a reflex action in the throat when mucus or any other foreign irritant is in it.

The Zexcy A 400mg/30mg Tablet consists of two medicines: Doxofylline (antibiotic) and Ambroxol (dilutes viscous cough). Doxofylline comes into the category of bronchodilators that relax the muscles of the airways and can widen up and breathe easily. On the other hand, Ambroxol is an 'expectorant' (promotes the secretion of sputum/cough) and a 'mucolytic agent' (makes sputum less viscous) to make breathing easier in asthma and COPD patients who have difficulty in breathing.

Take Zexcy A 400mg/30mg Tablet preferably with food to avoid stomach upset and swallow whole with a glass of water. Do not crush, chew, or break it. Your doctor will recommend how often you take Zexcy A 400mg/30mg Tablet based on your medical condition. Some people may experience nausea, taste change, stomach pain, photosensitivity, and numbness in the mouth, tongue, and throat. Most of these side effects of Zexcy A 400mg/30mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before using Zexcy A 400mg/30mg Tablet tell your doctor if you ever had an allergy to Zexcy A 400mg/30mg Tablet have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), muscle disease (myasthenia gravis). Please do not drink alcohol with Zexcy A 400mg/30mg Tablet as it may increase unpleasant side effects like drowsiness and dizziness. Zexcy A 400mg/30mg Tablet is pregnancy category D (high risk) medicines, so its use in pregnant and nursing mothers is not recommended. Use of Zexcy A 400mg/30mg Tablet during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent staining of teeth (yellow-grey-brown). Its use should be avoided by pregnant women, breastfeeding mothers, and children below 8 years of age. Do not consume alcohol as it may cause excessive drowsiness when taken along with Zexcy A 400mg/30mg Tablet.
 

Uses of Zexcy A 400mg/30mg Tablet

Treatment of Chronic Obstructive Pulmonary Diseases (COPD), Asthma.

Medicinal Benefits

Zexcy A 400mg/30mg Tablet is used to treat and prevent respiratory disorders like asthma attacks and chronic obstructive pulmonary diseases (COPD). Zexcy A 400mg/30mg Tablet is a combination of two medicines: Doxofylline and Ambroxol. Doxofylline (also known as Doxophylline) belongs to the class of bronchodilators. It works by relaxing muscles and widening the airways of the lungs. It minimizes the lung's airflow obstruction, relieving chest tightness, wheezing, and cough to make breathing easier. While  Ambroxol works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Zexcy A 400mg/30mg Tablet breakdown the acid mucopolysaccharide fibres that make the mucous (sputum) thinner and less dense/viscous, removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained.

Directions for Use

Take this medicine as prescribed by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zexcy A 400mg/30mg Tablet

  • Nausea
  • Vomiting
  • Taste change
  • Stomach pain
  • Photosensitivity
  • Palpitations
  • Headache
  • Insomnia
  • Dizziness
  • Numbness in the mouth, tongue, and throat
  • Dryness of mouth or throat
  • Taste changes

Drug Warnings

Let your doctor know if you have any allergic reactions to medicines. Please inform your doctor if you have any history of heart, liver, and kidney diseases. Also, tell your doctor if you have a stomach ulcer, seizure (fits), high blood pressure, and diabetes before taking Zexcy A 400mg/30mg Tablet. Zexcy A 400mg/30mg Tablet causes hypokalaemia (low potassium levels in the blood), therefore should be used with caution in patients with bronchospasm. Special precautions should be taken in patients with hyperthyroidism and epilepsy. Zexcy A 400mg/30mg Tablet can cause a rise in blood glucose levels. Hence monitor your blood glucose levels if you have diabetes and inform your doctor so that the dose can be adjusted accordingly. Let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. If you unexpectedly go into early labour or premature labour (before 9 months) or threatened abortion, do not use Zexcy A 400mg/30mg Tablet and consult a doctor.

Drug Interactions

Drug-Drug Interactions: Zexcy A 400mg/30mg Tablet may interact with indigestion remedies (antacids), supplements that contain aluminium, bismuth, calcium, magnesium or zinc, stomach ulcer medicines that contain bismuth, iron supplements, other antibiotics (rifampicin), acne medicines that contain vitamin A, such as isotretinoin, a blood thinner called warfarin, medicines for epilepsy, such as phenytoin or carbamazepine, and ciclosporin, a medicine to damp down your immune system.

Drug-Food Interactions: Limit alcohol intake since it may cause a rise in blood pressure leading to heart diseases. Avoid fatty foods and control your cholesterol and triglyceride levels.

Drug-Disease Interactions: Zexcy A 400mg/30mg Tablet is contraindicated in patients with heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (congenital disability caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxemia (low oxygen levels in the blood), stomach ulcers, and viral infections.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • RIFAMPICIN
  • CICLOSPORIN
  • CARBAMAZEPINE
  • WARFARIN
  • ISOTRETINOIN
  • VITAMIN A
  • CALCIUM
  • ZINC

Habit Forming

No

Diet & Lifestyle Advise

  • Take Zexcy A 400mg/30mg Tablet as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Zexcy A 400mg/30mg Tablet.
  • Know your triggers like allergens, such as pollen, dust, and food items that make your asthma severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Drink warm fluids while you take Zexcy A 400mg/30mg Tablet to help loosen congestion and lubricate the throat.

Special Advise

  • It is advised to inform your doctor beforehand if you are using Zexcy A 400mg/30mg Tablet and are advised to undergo any blood examinations since Zexcy A 400mg/30mg Tablet may cause eosinophilia (increased white blood cell count).  
  • It is advised to consult a Psychiatrist if you notice any mood changes like suicidal thoughts, aggressive behaviour, anxiety, depression, abnormal dreams, and hallucinations while using Zexcy A 400mg/30mg Tablet. 

Disease/Condition Glossary

Asthma: It is a breathing problem in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. Due to this, a whistling sound is produced during normal breathing. Symptoms of asthma include coughing, wheezing, and chest tightness.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases that block airflow and make it difficult to breathe. The most common conditions that makeup COPD are emphysema and chronic bronchitis. The main cause of COPD is tobacco chewing or smoking for a longer duration, which exposes the lungs to chemical irritants resulting in COPD.

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Alcohol

Unsafe

Avoid drinking alcohol while taking Zexcy A 400mg/30mg Tablet as it can worsen your condition, causing sleep disturbances (sleep apnoea).

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Pregnancy

Caution

There is limited data on how Zexcy A 400mg/30mg Tablet affects pregnancy. Please consult your doctor if you are planning to conceive or are already pregnant before starting Zexcy A 400mg/30mg Tablet.

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Breast Feeding

Caution

There is limited data on how Zexcy A 400mg/30mg Tablet affects breastfeeding. However, Doxofylline is contraindicated in breastfeeding. Please consult your doctor if you have concerns.

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Driving

Caution

Do not drive or operate machinery if you experience drowsiness, increased/uneven heart rate, and shakiness while using Zexcy A 400mg/30mg Tablet. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Zexcy A 400mg/30mg Tablet should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or pre-existing liver problems. Your doctor will weigh the benefits and potential risks before prescribing Zexcy A 400mg/30mg Tablet.

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Kidney

Caution

Zexcy A 400mg/30mg Tablet should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Zexcy A 400mg/30mg Tablet.

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Children

Caution

Zexcy A 400mg/30mg Tablet is not recommended for use for children less than 6 years of age. Your doctor will decide the dose depending on the condition of the child's disease and age.

Country of origin

India
Other Info - ZE65236

Author Details

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FAQs

Zexcy A 400mg/30mg Tablet is used to treat cough associated with respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD).
It is advised to never use cough suppressant medicine like Codeine with Zexcy A 400mg/30mg Tablet as it can suppress mucus expectoration unless prescribed by a doctor.
It is advised to tell your doctor if you are using contraceptives to prevent pregnancy, as Zexcy A 400mg/30mg Tablet may make contraceptives less effective.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.
Zexcy A 400mg/30mg Tablet should not be taken with any medication used for seizures or fits, as it might worsen your condition.
It is essential to let your doctor know if you have any history of heart, liver, kidney, and lung diseases, neuropsychiatric disorders like seizures (fits) and depression, phenylketonuria (birth defect caused by the build-up of an amino acid called phenylalanine in the body), hyperthyroidism (overactive thyroid), high blood pressure, hypoxemia (low levels of oxygen in the blood), stomach ulcers, and viral infections before taking Zexcy A 400mg/30mg Tablet.
Do not stop taking Zexcy A 400mg/30mg Tablet even if you feel better, as it may worsen your condition. For the best advice, consult your doctor and do as recommended.
Zexcy A 400mg/30mg Tablet can cause a rise in blood glucose levels. Hence monitor your blood glucose levels if you have diabetes and inform your doctor so that the dose can be adjusted accordingly.

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