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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:38 PM IST
Valgaciv-450 Tablet 10's is used to treat cytomegalovirus retinitis (viral infection of the retina). It contains Valganciclovir which works by inhibiting the multiplication of the virus. In some cases, this medicine may cause side effects such as diarrhoea, loss of appetite, cough, headache, stomach pain, nausea, fever, and tiredness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Zee Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Valgaciv-450 Tablet 10's

Valgaciv-450 Tablet 10's is used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, Valgaciv-450 Tablet 10's is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV. Cytomegalovirus (CMV) retinitis is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus.

Valgaciv-450 Tablet 10's contains Valganciclovir which works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  

Take Valgaciv-450 Tablet 10's as prescribed by your doctor. You are advised to take Valgaciv-450 Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects of Valgaciv-450 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Valgaciv-450 Tablet 10's or any other medicines, please tell your doctor. Avoid taking Valgaciv-450 Tablet 10's if you are pregnant, as it may cause birth defects. If you are breastfeeding, do not take Valgaciv-450 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valgaciv-450 Tablet 10's and for 30 days after treatment with Valgaciv-450 Tablet 10's. Drive only if you are alert, as Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness, or confusion.

Uses of Valgaciv-450 Tablet 10's

Treatment of Cytomegalovirus (CMV) infection of the retina.

Medicinal Benefits

Valgaciv-450 Tablet 10's contains Valganciclovir, an antiviral drug used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Valgaciv-450 Tablet 10's gets converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.  Additionally, Valgaciv-450 Tablet 10's is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.

Directions for Use

Take Valgaciv-450 Tablet 10's with food or as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Valgaciv-450 Tablet 10's

  • Diarrhoea

  • Loss of appetite

  • Cough

  • Headache

  • Stomach pain

  • Nausea

  • Fever

  • Tiredness

  • Sinusitis (sinus infection)

Drug Warnings

If you are allergic to Valgaciv-450 Tablet 10's or any other medicines, please tell your doctor. If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valgaciv-450 Tablet 10's. Avoid taking Valgaciv-450 Tablet 10's if you are pregnant as it may cause birth defects. If you are breastfeeding, do not take Valgaciv-450 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby. Women are recommended to use effective contraceptive measures while taking Valgaciv-450 Tablet 10's and 30 days after treatment with Valgaciv-450 Tablet 10's. Men are advised to continue using contraceptive measures for 90 days after treatment with Valgaciv-450 Tablet 10's. Drive only if you are alert as Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness or confusion. If you are having blood dialysis or radiotherapy, please inform your doctor before taking Valgaciv-450 Tablet 10's.

Drug Interactions

Drug-Drug Interaction: Valgaciv-450 Tablet 10's may interact with antibiotics (imipenem + cilastatin, trimethoprim, dapsone), gout medicine (probenecid), antifungals (amphotericin B, flucytosine), antiprotozoals (pentamidine), anti-cancer (vinblastine, hydroxyurea, vincristine, doxorubicin), immunosuppressants (tacrolimus, mycophenolate mofetil, ciclosporin), HIV/AIDS medicines (tenofovir, zidovudine, stavudine, didanosine), medicines used to treat hepatitis B infection (adefovir).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have a low number of platelets, white blood cells or red blood cells and kidney problems, inform your doctor before taking Valgaciv-450 Tablet 10's.

Drug-Drug Interactions Checker List

  • TRIMETHOPRIM
  • DAPSONE
  • PROBENECID
  • AMPHOTERICIN B
  • IMIPENEM+CILASTATIN
  • FLUCYTOSINE
  • PENTAMIDINE
  • VINBLASTINE
  • HYDROXYUREA
  • VINCRISTINE
  • DOXORUBICIN
  • TACROLIMUS
  • MYCOPHENOLATE MOFETIL
  • CICLOSPORIN
  • TENOFOVIR DISOPROXIL
  • ZIDOVUDINE
  • STAVUDINE
  • ADEFOVIR
  • DIDANOSINE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.

  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.

  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.

Special Advise

  • Regular eye tests are recommended if you have a history of cytomegalovirus retinitis to identify issues related to eye health.

  • If you touch damaged tablets accidentally, wash your hands with soap and water thoroughly. If any powder from tablets gets into your eyes, rinse with sterile or clean water.

Disease/Condition Glossary

Cytomegalovirus (CMV) retinitis: It is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus. In serious cases, it may lead to blindness. CMV retinitis is more likely to affect people with a weakened immune system from HIV/AIDS. The symptoms include blurred vision, a blind spot in vision, floaters in the eye, loss of peripheral vision or flashes in the eye.

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Alcohol

Caution

The interaction of alcohol with Valgaciv-450 Tablet 10's is unknown. Please consult a doctor before consuming alcohol while using Valgaciv-450 Tablet 10's.

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Pregnancy

Unsafe

Valgaciv-450 Tablet 10's is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Valgaciv-450 Tablet 10's as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.

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Driving

Caution

Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness or confusion in some people. Therefore, avoid driving or operating heavy machinery if you experience any of these symptoms after taking Valgaciv-450 Tablet 10's.

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Liver

Caution

Take Valgaciv-450 Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Valgaciv-450 Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Valgaciv-450 Tablet 10's should be used in children only if recommended by a doctor.

Country of origin

India

Manufacturer/Marketer address

Uchani, G.T. Road, Karnal-132001 Haryana (INDIA).
Other Info - VAL0571

Author Details

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FAQs

Valgaciv-450 Tablet 10's is used to treat cytomegalovirus (CMV) infection of the retina of the eye in adult AIDS patients. Also, it is used to prevent CMV infection in patients who received an organ transplant from a donor infected with CMV.
Valgaciv-450 Tablet 10's contains Valganciclovir that works by getting converted to ganciclovir in the body and inhibits the multiplication of the virus. Thereby, it helps to control the infection.
Valgaciv-450 Tablet 10's may be used to prevent cytomegalovirus infection in patients who received an organ transplant from a donor infected with CMV.
Valgaciv-450 Tablet 10's may cause diarrhoea as a temporary side effect. However, if the condition persists or worsens, please consult a doctor.
Valgaciv-450 Tablet 10's should be used with caution in patients with kidney problems and only in doses as prescribed by a doctor. However, regular blood tests are recommended while taking Valgaciv-450 Tablet 10's to monitor kidney functioning.
You are not recommended to take Valgaciv-450 Tablet 10's with tacrolimus (immunosuppressant) as it may increase the risk of kidney or nerve damage, cause side effects affecting bone marrow function leading to a low number of blood cells. Therefore, please consult a doctor before taking Valgaciv-450 Tablet 10's with other medicines.
Valgaciv-450 Tablet 10's is classed as a cytotoxic medicine and will therefore require special handling.
Common side effects of Valgaciv-450 Tablet 10's may include diarrhea, loss of appetite, cough, headache, stomach pain, nausea, fever, tiredness, or sinusitis (sinus infection). Most of these side effects of Valgaciv-450 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Yes, it also have activity against the alpha herpesviruses. But it should be taken only if recommended by the healthcare professional.
Valgaciv-450 Tablet 10's contains Valganciclovir as an active ingredient.
It is a viral infection of the retina (light-sensing cells) caused by cytomegalovirus. In serious cases, it may lead to blindness. CMV retinitis is more likely to affect people with a weakened immune system from HIV/AIDS. The symptoms include blurred vision, a blind spot in vision, floaters in the eye, loss of peripheral vision or flashes in the eye.
Valgaciv-450 Tablet 10's is not recommended for pregnant women as it may cause birth defects. Please consult a doctor if you are pregnant or have any concerns.
If you are breastfeeding, do not take Valgaciv-450 Tablet 10's as it may be excreted in human milk and cause adverse effects in the baby.
Valgaciv-450 Tablet 10's may cause dizziness, tiredness, drowsiness, shakiness or confusion in some people. Therefore, avoid driving or operating heavy machinery if you experience these symptoms after taking Valgaciv-450 Tablet 10's.

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