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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST

Trivon Tablet is an antidepressant medicine used in the treatment of moderate to severe depression. This medicine contains tranylcypromine, which works by preventing the breakdown of the levels of serotonin and noradrenaline in the brain, thus helping treat depression. You may experience common side effects like dizziness, dry mouth, insomnia, headache, and constipation.

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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Trivon Tablet

Trivon Tablet belongs to the group of antidepressants called monoamine oxidase inhibitors used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression. Depression is a mood disorder characterised by a persistently low mood and loss of interest in activities one used to enjoy earlier, leading to significant challenges in day-to-day functioning.

Trivon Tablet contains 'Tranylcypromine, ' which works by preventing the breakdown of the brain's levels of mood-uplifters serotonin and noradrenaline. Trivon Tablet helps restore the normal level of serotonin and noradrenaline, thereby helping treat depression.

Always take Trivon Tablet at the dose and duration prescribed by the doctor. Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. Trivon Tablet may cause certain common side effects, such as dizziness, dry mouth, insomnia, headache, and constipation. You are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of the components of Trivon Tablet . Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding. Trivon Tablet is not recommended for use in children below 18 years. Avoid taking alcohol with Trivon Tablet . Trivon Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

Uses of Trivon Tablet

Treatment of Depression

Medicinal Benefits

Trivon Tablet belongs to the group of antidepressants called monoamine oxidase inhibitors used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression. Trivon Tablet is used when no other antidepressant has worked. Trivon Tablet contains Tranylcypromine, which works by preventing the breakdown of feel-good hormones serotonin and noradrenaline, thereby increasing their concentrations in the brain. Thus, Trivon Tablet eases the major symptoms of depression, such as low mood, loss of interest in daily activities, fatigue, etc.

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it. Always take Trivon Tablet in the dose and duration prescribed by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trivon Tablet

  • Dizziness
  • Drowsiness
  • Dry mouth
  • Headache
  • Constipation
  • Weakness

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Trivon Tablet . Do not take Trivon Tablet if you are taking any other monoamine oxidase inhibitors (MAOI) or have taken them in the past 14 days; if you have taken clomipramine or imipramine in the past 21days or are planning to take them within the next 21days; if you have porphyria, severe heart disease, disease of blood vessels of the brain, pheochromocytoma, overactive thyroid, liver damage or disorder affecting blood cells. Inform your doctor if you have a mild heart problem, high blood pressure, diabetes, seizures, or if you are elderly or are due to undergo any surgery. Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding. Trivon Tablet is not recommended for use in children below 18 years. Avoid taking alcohol with Trivon Tablet . Trivon Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

Drug Interactions

Drug-Drug Interactions: Trivon Tablet may interact with sympathomimetic agents (ephedrine, pseudoephedrine, adrenaline, noradrenaline), antidepressants (amitriptyline, imipramine, tryptophan, clomipramine, bupropion), medicines used to treat Parkinson's disease (levodopa), medicines used to control appetite (amphetamine, fenfluramine), heart medications (dopamine), pain killers (pethidine, nefopam), general anaesthetic (propofol), anti-anxiety (buspirone). Inform your doctor if you are taking other MAOI (isocarboxazid), pain killer (codeine), barbiturates (amylobarbitone), antidepressants (fluoxetine, sertraline, doxepin), anti-hypertensive (guanethidine, reserpine, methyldopa), anti-diabetic (insulin, metformin), antihistamine (cetirizine), Antabuse medication (disulfiram).

Drug-Food Interactions: Trivon Tablet may interact with alcohol (especially red wine), caffeine, chocolate, and tyramine-rich foods such as soy-based foods, kimchee salads, banana skins, broad bean pods, yeast extracts (e.g., Bovril or Marmite), matured cheeses (e.g., cheddar or processed cheese made from mature cheese), meat, poultry, or fish that is not fresh or has been pickled.

Drug-Disease Interactions: Trivon Tablet should be used with caution in patients with a known history of substance abuse (individual or within the family), hypersensitivity disorder, epilepsy, phaeochromocytoma, blood disorders, hypertension, diabetes, hyperthyroidism, goitre, porphyria, liver disease, heart problems or any mental health disorders.

Drug-Drug Interactions Checker List

  • EPHEDRINE
  • PSEUDOEPHEDRINE
  • ADRENALINE
  • NORADRENALINE
  • AMITRIPTYLINE
  • IMIPRAMINE
  • TRYPTOPHAN
  • CLOMIPRAMINE
  • BUPROPION
  • LEVODOPA
  • AMPHETAMINE
  • DOPAMINE
  • PETHIDINE
  • NEFOPAM
  • PROPOFOL
  • BUSPIRONE
  • ISOCARBOXAZID
  • CODEINE
  • FLUOXETINE
  • SERTRALINE
  • DOXEPIN
  • GUANETHIDINE
  • RESERPINE
  • METHYLDOPA
  • INSULIN
  • METFORMIN
  • CETIRIZINE
  • DISULFIRAM
  • FENFLURAMINE
  • AMYLOBARBITONE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Invest in a balanced diet. 
  • Try yoga and exercise for at least 30 minutes every day. Physical activity can help counteract low moods. 
  • Cut back on caffeine, chocolate, and tyramine-rich foods such as matured cheeses, yeast, chicken liver, kimchee salad, etc., as they may interact with Trivon Tablet .
  • Cut back on alcohol, as this can have an adverse effect on your sleep.
  • Try meditation and deep breathing exercises to reduce overall stress.
  • Invest in cognitive behaviour therapy and see a counsellor for a holistic approach to depression. 
  • Maintaining a gratitude journal and listing 5 things you are grateful for every day can have a profound impact on easing depression.

Special Advise

  • If you have suicidal thoughts or thoughts of harming/killing yourself, consult your doctor immediately. 
  • If you are due to undergo any surgery, inform the doctor/surgeon that you are taking Trivon Tablet .

Disease/Condition Glossary

Depression: Depression is a mood disorder characterised by a persistently low mood and loss of interest in activities one used to enjoy earlier, leading to significant challenges in day-to-day functioning. Various factors can contribute to depression. These can range from genetics, nutrient deficiencies, and lack of physical activity to emotional, psychological, environmental, and social factors.

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Alcohol

Unsafe

There can be a reaction of alcohol with Trivon Tablet . Use of Trivon Tablet with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Trivon Tablet is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Trivon Tablet passes in breast milk and should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Trivon Tablet may cause drowsiness or dizziness. Exercise caution and do not drive or operate machinery unless you are alert.

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Liver

Caution

Exercise caution before using Trivon Tablet in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Trivon Tablet in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Trivon Tablet is not recommended for use in children below 18 years of age. Please consult your physician if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TRI1474

Author Details

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FAQs

Trivon Tablet is used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression.
Trivon Tablet works by inhibiting the breakdown of serotonin and noradrenalin and subsequently enhancing their concentrations in the brain.
Trivon Tablet contains Tranylcypromine which prevents the breakdown of a substance called tyramine found in certain foods. It can cause very high blood pressure if this substance is not broken down. Therefore, while taking Trivon Tablet , avoid consuming foods such as banana skins, broad bean pods, yeast extracts (e.g. Bovril or Marmite), matured cheeses (e.g. cheddar or processed cheese made from mature cheese), meat, poultry, or fish which is not fresh or has been pickled.
Do not stop taking Trivon Tablet on your own. Stopping Trivon Tablet suddenly may cause nausea, vomiting, difficulty sleeping, and sweating. Consult your doctor if you experience any difficulty while taking Trivon Tablet , your doctor may reduce the dose gradually.
In some cases, Trivon Tablet may cause low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Trivon Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. Talk to your doctor if you regularly experience postural hypotension.
If you are suffering from bipolar disorder, you might be on medication for the same. Trivon Tablet should be used with caution along with other psychoactive drugs. Consult your doctor before use.

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