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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Trivon Tablet is an antidepressant medicine used in the treatment of moderate to severe depression. This medicine contains tranylcypromine, which works by preventing the breakdown of the levels of serotonin and noradrenaline in the brain, thus helping treat depression. You may experience common side effects like dizziness, dry mouth, insomnia, headache, and constipation.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trivon Tablet

Trivon Tablet belongs to the group of antidepressants called monoamine oxidase inhibitors used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression. Depression is a mood disorder characterised by a persistently low mood and loss of interest in activities one used to enjoy earlier, leading to significant challenges in day-to-day functioning.

Trivon Tablet contains 'Tranylcypromine, ' which works by preventing the breakdown of the brain's levels of mood-uplifters serotonin and noradrenaline. Trivon Tablet helps restore the normal level of serotonin and noradrenaline, thereby helping treat depression.

Always take Trivon Tablet at the dose and duration prescribed by the doctor. Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. Trivon Tablet may cause certain common side effects, such as dizziness, dry mouth, insomnia, headache, and constipation. You are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of the components of Trivon Tablet . Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding. Trivon Tablet is not recommended for use in children below 18 years. Avoid taking alcohol with Trivon Tablet . Trivon Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

Uses of Trivon Tablet

Treatment of Depression

Directions for Use

Swallow it as a whole with a glass of water. Do not crush, chew or break it. Always take Trivon Tablet in the dose and duration prescribed by the doctor.

Medicinal Benefits

Trivon Tablet belongs to the group of antidepressants called monoamine oxidase inhibitors used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression. Trivon Tablet is used when no other antidepressant has worked. Trivon Tablet contains Tranylcypromine, which works by preventing the breakdown of feel-good hormones serotonin and noradrenaline, thereby increasing their concentrations in the brain. Thus, Trivon Tablet eases the major symptoms of depression, such as low mood, loss of interest in daily activities, fatigue, etc.

How Trivon Tablet Works

Trivon Tablet contains 'Tranylcypromine, ' which works by preventing the breakdown of the brain's levels of mood-uplifters serotonin and noradrenaline. Trivon Tablet helps restore the normal level of serotonin and noradrenaline, thereby helping treat depression.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of Trivon Tablet

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include difficulty falling asleep or staying asleep, restlessness, anxiety, agitation, confusion, unclear speech, dizziness, weakness, drowsiness, headache, muscle twitching, fever, stiffness, and coma (loss of consciousness for a period of time). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of the components of Trivon Tablet . Do not take Trivon Tablet if you are taking any other monoamine oxidase inhibitors (MAOI) or have taken them in the past 14 days; if you have taken clomipramine or imipramine in the past 21days or are planning to take them within the next 21days; if you have porphyria, severe heart disease, disease of blood vessels of the brain, pheochromocytoma, overactive thyroid, liver damage or disorder affecting blood cells. Inform your doctor if you have a mild heart problem, high blood pressure, diabetes, seizures, or if you are elderly or are due to undergo any surgery. Consult your doctor if you are pregnant, planning to get pregnant or breastfeeding. Trivon Tablet is not recommended for use in children below 18 years. Avoid taking alcohol with Trivon Tablet . Trivon Tablet may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

Drug-Drug Interactions

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TranylcypromineLevomilnacipran
Critical
TranylcypromineSafinamide
Critical

Drug-Drug Interactions

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TranylcypromineLevomilnacipran
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Levomilnacipran can increases the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is a of interaction between Levomilnacipran and Trivon Tablet, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcypromineSafinamide
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Safinamide can increase the risk of high blood pressure and serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Trivon Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TranylcypromineTrazodone
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with trazodone can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Trivon Tablet with Trazodone is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcyprominePethidine
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Meperidine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Pethidine with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcypromineCyclobenzaprine
Critical
How does the drug interact with Trivon Tablet:
Coadministration of Cyclobenzaprine with Trivon Tablet might raise serotonin hormone levels which can increase the risk of developing side effects.

How to manage the interaction:
Taking Trivon Tablet with Cyclobenzaprine is not recommended, but can be taken together if prescribed by a doctor. However, if you experience fever, palpitations, excessive sweating, muscle spasm, or diarrhea, contact a doctor immediately. Do not discontinue the medications without consulting a doctor.
TranylcypromineEntacapone
Critical
How does the drug interact with Trivon Tablet:
Coadministration of Entacapone with Trivon Tablet can increase the risk of high blood pressure and also increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Entacapone with Trivon Tablet can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcypromineTryptophan
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with tryptophan can increase the risk of serotonin syndrome ( high levels of serotonin in body which result in shivering, high fever, diarrhea & muscle stiffness) .

How to manage the interaction:
Taking Trivon Tablet with Tryptophan is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcypromineOxcarbazepine
Critical
How does the drug interact with Trivon Tablet:
Combining Trivon Tablet with Oxcarbazepine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Oxcarbazepine with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TranylcyprominePropofol
Critical
How does the drug interact with Trivon Tablet:
Taking Trivon Tablet with Propofol may significantly affect your blood pressure.

How to manage the interaction:
Taking Propofol with Trivon Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting your doctor.
TranylcypromineZolmitriptan
Critical
How does the drug interact with Trivon Tablet:
Combining Trivon Tablet with Zolmitriptan can increase the risk of serotonin syndrome.

How to manage the interaction:
Taking Trivon Tablet with Zolmitriptan is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, it's a good idea to reach out to your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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TRANYLCYPROMINE-10MGTyramine-containing food
Severe

Drug-Food Interactions

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TRANYLCYPROMINE-10MGTyramine-containing food
Severe
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming high-tyramine-containing foods with Trivon Tablet can raise your blood pressure to dangerous levels. Avoid high-tyramine-containing foods while being treated with Trivon Tablet. However, if you experience severe headaches, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, and sudden numbness or weakness (especially on one side of the body), such as an abnormal heartbeat, chest tightness, blurred vision, or nausea, consult a doctor.

Diet & Lifestyle Advise

  • Invest in a balanced diet. 
  • Try yoga and exercise for at least 30 minutes every day. Physical activity can help counteract low moods. 
  • Cut back on caffeine, chocolate, and tyramine-rich foods such as matured cheeses, yeast, chicken liver, kimchee salad, etc., as they may interact with Trivon Tablet .
  • Cut back on alcohol, as this can have an adverse effect on your sleep.
  • Try meditation and deep breathing exercises to reduce overall stress.
  • Invest in cognitive behaviour therapy and see a counsellor for a holistic approach to depression. 
  • Maintaining a gratitude journal and listing 5 things you are grateful for every day can have a profound impact on easing depression.

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT
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Alcohol

Unsafe

There can be a reaction of alcohol with Trivon Tablet . Use of Trivon Tablet with alcohol is hence not recommended. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Trivon Tablet is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Trivon Tablet passes in breast milk and should be used with caution during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Unsafe

Trivon Tablet may cause drowsiness or dizziness. Exercise caution and do not drive or operate machinery unless you are alert.

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Liver

Caution

Exercise caution before using Trivon Tablet in case of liver conditions. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Trivon Tablet in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Trivon Tablet is not recommended for use in children below 18 years of age. Please consult your physician if you have any concerns.

FAQs

Trivon Tablet is used to treat moderate to severe depression. It may also help in treating phobia occurring due to depression.

Trivon Tablet works by inhibiting the breakdown of serotonin and noradrenalin and subsequently enhancing their concentrations in the brain.

Trivon Tablet contains Tranylcypromine which prevents the breakdown of a substance called tyramine found in certain foods. It can cause very high blood pressure if this substance is not broken down. Therefore, while taking Trivon Tablet , avoid consuming foods such as banana skins, broad bean pods, yeast extracts (e.g. Bovril or Marmite), matured cheeses (e.g. cheddar or processed cheese made from mature cheese), meat, poultry, or fish which is not fresh or has been pickled.

Do not stop taking Trivon Tablet on your own. Stopping Trivon Tablet suddenly may cause nausea, vomiting, difficulty sleeping, and sweating. Consult your doctor if you experience any difficulty while taking Trivon Tablet , your doctor may reduce the dose gradually.

In some cases, Trivon Tablet may cause low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking Trivon Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. Talk to your doctor if you regularly experience postural hypotension.

If you are suffering from bipolar disorder, you might be on medication for the same. Trivon Tablet should be used with caution along with other psychoactive drugs. Consult your doctor before use.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - TRI1474

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