TRILOSAR 12.5MG TABLET is used to treat high blood pressure, heart failure, and oedema (a buildup of fluid in the body). Hypertension or high blood pressure is a lifelong or chronic condition in which the force exerted by the blood against the blood vessel (artery wall) increases. The higher this blood pressure, the harder the heart has to pump. Oedema may occur in high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles and legs, leading to swelling.

TRILOSAR 12.5MG TABLET contains Chlorothiazide, Losartan and Amlodipine. Chlorothiazide is a diuretic that works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Edema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine is a calcium channel blocker, and Losartan is an angiotensin receptor antagonist. Both work by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take TRILOSAR 12.5MG TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take TRILOSAR 12.5MG TABLET for as long as your doctor has prescribed it for you. You may experience glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid and altered blood lipid level. Most of these side effects of TRILOSAR 12.5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Tell your doctor about this, as it may cause a rise in blood pressure and increase the risk of heart complications like stroke and heart disease. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. Taking TRILOSAR 12.5MG TABLET during pregnancy may cause side effects like jaundice (yellowing of the skin or eyes), unexplained bleeding, low blood sugar or an electrolyte imbalance in the newborn baby. Do not use the TRILOSAR 12.5MG TABLET if you cannot urinate, have low blood pressure (hypotension), and have a cardiogenic shock (sudden stopping blood flow to the heart). Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

TRILOSAR 12.5MG TABLET is a combination drug used to treat hypertension. When you take TRILOSAR 12.5MG TABLET , your body's blood vessels will be relaxed, and it will help lower the raised blood pressure. It also widens the blood vessels (lining of arteries wall) and improves blood flow. It helps in losing out excess fluids from the body by increasing the production of urine. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. TRILOSAR 12.5MG TABLET also helps decrease fluid buildup, which reduces inflammation or swelling. In addition, this relieves Oedema and enables you to carry out your daily activities more efficiently.

• Glucose intolerance (low or high level of glucose)
• Ankle swelling
• Sleepiness
• Headache (sense of heat in the face, ears, neck, and trunk)
• Flushing
• Tiredness
• Decreased potassium level in the blood
• Increased blood uric acid
• Altered blood lipid level

TRILOSAR 12.5MG TABLET should not be given to the people allergic to TRILOSAR 12.5MG TABLET , have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, gout (high uric acid), high cholesterol (hyperlipidemia), pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in people with cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). TRILOSAR 12.5MG TABLET can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take TRILOSAR 12.5MG TABLET and breastfeeding. Tell your doctor if you are on low sodium (table salt) diet. Cases of electrolyte imbalance have been observed (like low levels of sodium, potassium, or magnesium in your blood). So your doctor might advise monitoring blood pressure, kidney function tests and electrolytes.

Drug-Drug Interactions: TRILOSAR 12.5MG TABLET may interact with other high blood pressure-lowering pills (e.g. metoprolol, ramipril, hydrochlorothiazide, atorvastatin), certain medicines to treat erectile dysfunction (e.g. sildenafil), anti-epilepsy medications (e.g. carbamazepine, phenobarbital), immune-suppressing drugs (e.g. cyclosporine), painkillers (e.g. ibuprofen, aspirin), anti-biotics (e.g. rifampicin), antipsychotics (e.g. ziprasidone, lithium).

Drug-Food Interactions: You are recommended not to consume alcohol with TRILOSAR 12.5MG TABLET to avoid unpleasant side effects.

Drug-Disease Interactions: TRILOSAR 12.5MG TABLET should not be given to people with cardiogenic shock (when the heart fails to pump required blood to the body), heart valve problem (stenosis), low blood pressure (hypotension), coronary heart disease, liver disease or heart failure, low serum potassium (hypokalemia), patients with nil urine output (anuria).

• METOPROLOL
• RAMIPRIL
• HYDROCHLOROTHIAZIDE
• ATORVASTATIN
• SILDENAFIL
• CARBAMAZEPINE
• PHENOBARBITAL
• CYCLOSPORINE
• IBUPROFEN
• ASPIRIN
• RIFAMPICIN
• ZIPRASIDONE
• LITHIUM

• Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.

• Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.

• Use healthy cooking oils like soybean, olive, canola, and coconut oil.

• You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.

• Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.

• Avoid the consumption of too much salt or salty food.

• Keep your weight under control with a BMI of 19.5-24.9.

• Regular physical activity or exercise like walking improves your blood flow.

• When possible, elevate your legs or the swollen area on a chair or pillows.

• Avoid standing or sitting for extended periods of time.

• Avoid chronic stress, as it can raise your blood pressure.

• Spend time with your loved ones to cope with stress and practice mindfulness techniques.

• Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.