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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:44 PM IST

Tresil 1mg Injection is used to treat Bleeding oesophageal varices. It contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting their flow. Thus, it helps to control bleeding.

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Composition :

TERLIPRESSIN-1MG

Manufacturer/Marketer :

Serum Institute Of India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Tresil 1mg Injection

Tresil 1mg Injection belongs to the class of drugs called vasopressin receptor agonists used for the treatment of bleeding oesophageal varices and the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver). Bleeding oesophageal varices occur when there is bleeding from dilated veins in the food pipe leading to your stomach.

Tresil 1mg Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

Tresil 1mg Injection will be administered by a healthcare professional; do not self-administer. Sometimes, Tresil 1mg Injection may cause common side effects such as headache, diarrhoea, abdominal cramps, high or low blood pressure, too slow heart rate, pale skin, and insufficient blood circulation in arms, legs and skin. Most of these side effects of Tresil 1mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Terlipressin or other medicines, please tell your doctor. Tresil 1mg Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Tresil 1mg Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Tresil 1mg Injection.

Uses of Tresil 1mg Injection

Treatment of Bleeding oesophageal varices

Medicinal Benefits

Tresil 1mg Injection contains Terlipressin used for the treatment of bleeding oesophageal varices. It narrows the affected blood vessels and restricts the blood flow through them. Thus, it helps to control bleeding. Also, it is used for the emergency treatment of type 1 hepatorenal syndrome (rapidly progressive kidney failure) in patients with ascites (abdominal swelling due to accumulation of fluid) and liver cirrhosis (scarring of the liver).

Side Effects of Tresil 1mg Injection

  • Headache
  • Diarrhoea
  • Abdominal cramps
  • High or low blood pressure
  • Too slow heart rate
  • Pale skin
  • Insufficient blood circulation in arms, legs and skin

Directions for Use

Tresil 1mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Terlipressin or any other medicines, please tell your doctor. Tresil 1mg Injection is not recommended for children and adolescents as the safety and effectiveness were not established. If you are a pregnant or breastfeeding woman, please inform your doctor before receiving Tresil 1mg Injection. If you are elderly above 70 years of age, discuss with your doctor before receiving Tresil 1mg Injection. If you experience dizziness, lightheadedness, or feeling faint, inform your doctor, as these could be signs of a low heart rate. Your heart and blood circulation will be monitored continuously while on treatment with Tresil 1mg Injection.

Therapeutic Class

VASOACTIVE DRUG

Diet & Lifestyle Advise

  • Eat a balanced diet consisting of whole grains, lean protein, low salt, fruits, and vegetables.
  • Maintain a healthy weight.
  • Avoid alcohol consumption.
  • Lower your risk for hepatitis (inflammation of the liver) by practising safer sex. Avoid sharing razors or needles, and avoid contact with the blood and other bodily fluids of a person who has hepatitis.

Habit Forming

No

How Tresil 1mg Injection Works

Tresil 1mg Injection contains Terlipressin, a synthetic pituitary hormone that breaks down in the body to release a substance called lysine vasopressin that is used to stop bleeding from leaking varicose veins in the food pipe. It works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.

What if I have taken an overdose of Tresil 1mg Injection

Since Tresil 1mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Consult your doctor

The interaction of Tresil 1mg Injection with alcohol is unknown. Therefore, if you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

Limited data available on the effect of Tresil 1mg Injection on pregnant women. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Tresil 1mg Injection. Your doctor may give this medicine if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Terlipressin is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before receiving Tresil 1mg Injection. Your doctor may give this medicine if the benefits outweigh the risks.

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Driving

Caution

Limited information is available. However, if you are unwell after receiving Tresil 1mg Injection, avoid driving or operating machinery.

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Liver

Consult your doctor

If you have any liver problems, inform your doctor before receiving Tresil 1mg Injection.

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Kidney

Caution

Tresil 1mg Injection should be used with caution in patients with long-standing kidney failure. Also, inform your doctor if you have impaired kidney function.

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Children

Unsafe

Tresil 1mg Injection is not recommended for children and adolescents as the safety and effectiveness were not established.

Country of origin

India
Other Info - TRES209

Author Details

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FAQs

Tresil 1mg Injection is used to treat Bleeding oesophageal varices.
Tresil 1mg Injection contains Terlipressin, a synthetic pituitary hormone that works by narrowing the affected blood vessels and restricting the blood flow through them. Thus, it helps to control bleeding.
You are recommended to consult a doctor before taking quinidine while on treatment with Tresil 1mg Injection as it may increase the risk or severity of QT prolongation (a heart rhythm disorder). Therefore, please consult a doctor before taking other medicines with Tresil 1mg Injection.
Tresil 1mg Injection may cause headaches as a common side effect. However, if the condition persists or worsens, please inform your doctor.
The side effects of Tresil 1mg Injection include abdominal cramps, diarrhoea, high or low blood pressure, slow heart rate, headache, pale skin, and insufficient blood circulation in arms, legs and skin. Consult the doctor if any of these symptoms persist or worsen.
Tresil 1mg Injection should not be taken if you are allergic to any of its ingredients, experiencing hypoxia (low levels of oxygen) or worsening respiratory symptoms, or have ongoing coronary, peripheral, or mesenteric ischemia (conditions affecting blood flow).
Before taking Tresil 1mg Injection, let your doctor know if you have severe bleeding in the oesophagus (food pipe). If you have a severe infection like septic shock, breathing issues such as asthma, uncontrolled high blood pressure, heart problems (angina, arrhythmias, or a history of heart attack), poor blood circulation (to the brain or limbs), kidney impairment, electrolyte imbalances, significant fluid or blood loss, if you are pregnant, or are over 70 years old.
Tresil 1mg Injection will be given as a continuous intravenous infusion by the doctor or nurse. Do not self-administer.
Tresil 1mg Injection is not recommended for children as its safety and effectiveness were not established.

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