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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
TRANOSTAT INJECTION 5ML is used to treat Abnormal heavy bleeding. It contains an anti-fibrinolytic drug, tranexamic acid, which helps the body's natural blood clotting system by reducing fibrin breakdown and inhibiting fibrinolysis, a process that limits the development of blood clots. As a result, it contributes to the prevention of excessive bleeding. Common side effects of TRANOSTAT INJECTION 5ML include feeling sick (nausea), diarrhoea, vomiting, itchy skin, and pain at the injection site.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Ozone Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About TRANOSTAT INJECTION 5ML

TRANOSTAT INJECTION 5ML belongs to the class of medications called ‘anti-fibrinolytic drugs. It is mainly used to treat abnormal bleeding in various conditions such as menorrhagia (heavy bleeding in periods), epistaxis (nose bleeds), cervical surgery (conization of the cervix), post-prostatectomy (prostate surgery), post-cystectomy (bladder surgery), traumatic hyphaema (bleeding inside the eye), before tooth removal (dental extraction) in hemophiliacs (people who bleed more easily than normal) and a hereditary disease called angioneurotic oedema (HANO).

TRANOSTAT INJECTION 5ML contains an anti-fibrinolytic drug, tranexamic acid. Tranexamic acid helps the body's natural blood clotting system by reducing fibrin breakdown, which inhibits fibrinolysis, a process that limits the development of blood clots. As a result, TRANOSTAT INJECTION 5ML contributes to the prevention of excessive bleeding.

TRANOSTAT INJECTION 5ML is a parenteral form. It will be administered by the healthcare professional; do not self-administer. TRANOSTAT INJECTION 5ML may cause side effects such as feeling sick (nausea), diarrhoea, vomiting, itchy skin, and pain at the injection site. These side effects usually disappear with time. However, consult your doctor immediately if these side effects persist or if you develop any other serious side effects, such as vision problems while using TRANOSTAT INJECTION 5ML.

If you are allergic to TRANOSTAT INJECTION 5ML or any other medicines, please inform your doctor. Inform your doctor if you have pre-existing or a history of kidney disease, disseminated intravascular coagulation (a disease where blood clots form throughout your body), thrombosis (formation of blood clots in the blood vessels) or seizures (fits), as this medicine is not recommended in such cases. Also, inform your doctor before receiving this injection if you are using any birth control pills or fibrinolytic agents (medicines that dissolve blood clots) or if you are pregnant, planning pregnancy or breastfeeding.

Uses of TRANOSTAT INJECTION 5ML

Treatment of Abnormal heavy bleeding

Medicinal Benefits

TRANOSTAT INJECTION 5ML contains tranexamic acid, which is an anti-fibrinolytic medication. Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, and this stops fibrinolysis, a process that stops blood clot formation. Thus TRANOSTAT INJECTION 5ML helps to prevent excessive bleeding.

Directions for Use

A healthcare professional will administer the injection, so do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TRANOSTAT INJECTION 5ML

  • Nausea
  • Diarrhoea
  • Itchy skin
  • Pain at the injection site
  • Injection site reactions
  • Vomiting

Drug Warnings

Before administering TRANOSTAT INJECTION 5ML, inform your doctor if you notice blood in your urine (except during periods), or have a history of uncontrollable bleeding, disseminated intravascular coagulation (DIC) (a disease where blood clots form throughout your body), irregular periods and kidney disease. Also, inform your doctor if you or your family has a history of thrombosis (formation of blood clots in the blood vessels). Let your doctor know if you are taking medicine to treat a hereditary disease called angioneurotic oedema (HANO) every day for a long time. Your doctor may advise regular eye tests and blood tests to check your vision problems and also liver/kidney functioning. Inform your doctor if you are using birth control pills, including the patch, vaginal ring, and an intrauterine device (IUD), as there is a risk of deep vein thrombosis (a condition in which a blood clot is formed in the deeper vein, mostly the legs). Inform your doctor if you are using fibrinolytic agents (drugs that break blood clots) such as streptokinase, as they may stop the effect of TRANOSTAT INJECTION 5ML. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding.

Drug Interactions

Drug-drug interactions: TRANOSTAT INJECTION 5ML may interact with fibrinolytic drugs (streptokinase, urokinase, reteplase, alteplase, and tenecteplase, etc.), an antipsychotic drug (chlorpromazine), and a drug used to treat blood cancer (tretinoin) and progestins (levonorgestrel).

Drug-food interactions: No interactions found.

Drug-disease interactions: TRANOSTAT INJECTION 5ML interacts with various disease conditions, including colour vision defect, active intravascular clotting, intracranial haemorrhage, seizures (fits) and renal dysfunction.

Drug-Drug Interactions Checker List

  • CHLORPROMAZINE
  • TRETINOIN
  • STREPTOKINASE
  • UROKINASE
  • LEVONORGESTREL

Habit Forming

No

Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
  • Stay hydrated; drink plenty of water.
  • Cut down on sugars, salts, spicy food, coffee, and alcohol.
  • A heating pad can help ease the pain by placing it on the belly or lower back.
  • Exercise can help ease the pain of menstrual cramps.
  • Avoid stress by performing meditation or yoga.
  • Massage your lower back or abdomen to relieve the pain.
  • Take proper rest.

Disease/Condition Glossary

Menorrhagia: It is a condition characterized by heavy or prolonged bleeding during menstrual periods which last for more than seven days

Epistaxis: Bleeding from the nose when the blood vessels of the nose lining burst. This can occur due to dryness or nose injury.

Post-operative bleeding: It is bleeding after surgery due to the blood vessel rupture. Some people may experience mild to severe bleeding due to cuts made during surgery.

Traumatic hyphema: It is a condition characterized by the presence of blood in the anterior chamber of the eye due to a blunt injury. This condition may also result in vision loss.

Hereditary angioneurotic oedema (HANO): Hereditary angioneurotic oedema is a hereditary disease that causes recurrent painless swelling under the skin.

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Alcohol

Caution

TRANOSTAT INJECTION 5ML may not interact with alcohol. However, avoid the consumption of alcohol as it may worsen your health condition.

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Pregnancy

Caution

TRANOSTAT INJECTION 5ML should not be used when pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing TRANOSTAT INJECTION 5ML.

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Breast Feeding

Caution

TRANOSTAT INJECTION 5ML should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing TRANOSTAT INJECTION 5ML.

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Driving

Caution

TRANOSTAT INJECTION 5ML does not affect your ability to drive or operate machinery. However, do not drive if you experience unwanted effects after taking TRANOSTAT INJECTION 5ML.

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Liver

Caution

No information is available on the use of TRANOSTAT INJECTION 5ML in patients with liver problems. Inform your doctor if you have liver conditions. Your doctor may adjust the dose or prescribe a suitable alternative if needed based on your health condition.

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Kidney

Caution

TRANOSTAT INJECTION 5ML should be used with caution in patients with kidney diseases. Inform your doctor if you have kidney conditions. Your doctor may adjust the dose or prescribe a suitable alternative if needed based on your health condition.

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Children

Caution

TRANOSTAT INJECTION 5ML should be used in children below 12 years of age only if clinically needed. The dose will be decided by your doctor based on your child's age and condition.

Country of origin

INDIA

Manufacturer/Marketer address

Ozone House, Block A-3, 1 LSC, Janak Puri, New Delhi – 110058
Other Info - TRA0153

FAQs

TRANOSTAT INJECTION 5ML is used to treat abnormal or unwanted bleeding.
TRANOSTAT INJECTION 5ML contains tranexamic acid, an anti-fibrinolytic drug. Tranexamic acid helps the body's natural blood clotting mechanism by reducing fibrin breakdown, which prevents fibrinolysis, a process that prevents blood clot formation. As a result, TRANOSTAT INJECTION 5ML helps to prevent excessive bleeding.
Taking this medication together with birth control pills may raise your chance of getting blood clots. To avoid pregnancy, use another method of birth control (such as condoms or spermicide). Consult your doctor in case of concerns.
People who have frequent nosebleeds or heavy periods can take tranexamic acid for a long time, for months or years. They normally only take it for a few days or a week at a time when the bleeding is severe. Take this medicine as your doctor prescribed.
Appropriate investigations have not revealed any geriatric-specific issues that would restrict the use of TRANOSTAT INJECTION 5ML in the elderly. However, senior people are more prone to develop age-related renal issues. Thus, patients getting this medication should exercise caution.

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