Toplap Gel is used to produce local numbness (anaesthesia) on the skin before surgical procedures or injections. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, constant or intermittent, and the tolerance level of pain might vary from person to person.

Toplap Gel is a combination of amide-type local anaesthetics: Lidocaine and Prilocaine. Toplap Gel blocks the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing the initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain.

Use Toplap Gel as suggested by your doctor. Do not apply it to broken, irritated skin or open wounds unless directed by your doctor. In some cases, you may experience certain common side effects, such as reactions at the application site (burning, itching, redness, and irritation). Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before using Toplap Gel, tell your doctor about your medical history, especially if you have broken skin/infection in the area where Toplap Gel is to be applied, heart disease, liver disease, or a certain blood disorder (methemoglobinemia). Inform your doctor before using Toplap Gel if you plan to get pregnant, are pregnant or breastfeeding. If Toplap Gel comes in contact with the eyes, nose, mouth, rectum, or vagina, rinse with water immediately. Do not apply Toplap Gel on the swollen skin areas or deep puncture wounds. Inform your doctor about your health condition and medications before using Toplap Gel to rule out any side effects.

Toplap Gel is a combination of amide-type local anaesthetics, namely, Lidocaine and Prilocaine. It is used to produce local numbness (anaesthesia). It is used to numb the normal, unbroken skin or the outer genital area to prevent pain before surgical procedures such as inserting a needle, skin grafts, or skin laser surgery. It works by blocking the transmission of nerve signals in the body, thereby helping to decrease the sensation of pain.

• ​​​​​​Itching
• Rash
• Mild burning at the site of the application
• Changes in skin colour at the site of application

Use the recommended dose of Toplap Gel to numb the skin. Do not exceed the dose and duration or cover treated skin areas with a bandage without the doctor's advice. In some cases, Toplap Gel can cause fatal side effects such as uneven heartbeats, seizure (convulsions), coma, slowed breathing or respiratory failure (breathing stops), if too much of the medicine is absorbed through the skin. Consult your doctor before using Toplap Gel if you are pregnant or breastfeeding, your doctor will prescribe you Toplap Gel only if the benefits outweigh the risks. Toplap Gel causes drowsiness, so drive with caution. Avoid consuming alcohol along with Toplap Gel as it could lead to increased drowsiness. Toplap Gel may not be suitable for people with a blood disorder, glucose-6-phosphate dehydrogenase (G6PD) deficiency, kidney or liver problems. Inform your doctor about your health condition and medications before using Toplap Gel to rule out any side effects.

Drug-Drug Interaction: Toplap Gel may interact with antimalarial drugs (chloroquine, quinine), medicines used to treat seizures (fits) (phenobarbital, phenytoin, primaquine), heart rhythm and blood pressure-lowering medication (amiodarone, dofetilide, dronedarone, mexiletine, sotalol, tocainide, nitroprusside, nitroglycerin, isosorbide), and antibiotics (nitrofurantoin).

Drug-Food Interaction: Avoid consuming alcohol along with Toplap Gel as it could lead to increased drowsiness.

Drug-Disease Interaction: Toplap Gel may interact with a blood disorder, heart dysfunction, liver problems and kidney dysfunction.

• CHLOROQUINE
• QUININE
• PHENOBARBITAL
• PHENYTOIN
• PRIMAQUINE
• AMIODARONE
• DOFETILIDE
• DRONEDARONE
• MEXILETINE
• TOCAINIDE
• SOTALOL
• NITROPRUSSIDE
• NITROGLYCERIN
• ISOSORBIDE DINITRATE
• NITROFURANTOIN

• ​​​​​​Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
• Avoid smoking and alcohol consumption.

• Do not apply near eyes or open wounds.
• Inform your doctor immediately if you develop blistering of the skin where the medication is applied.

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or intermittent. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). Pain can be considered a good thing as it helps us know something is wrong in the body and helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, stomach aches, etc.