Tolfen Capsule is used to relieve signs and symptoms of osteoarthritis of the hip and knee. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Tolfen Capsule contains Polmacoxib, which works by inhibiting the cyclo-oxygenase-2 (COX-2) enzyme in the body. This enzyme is involved in producing certain chemical substances called prostaglandins that cause pain and swelling. Thus, it helps relieve pain and swelling.

Take Tolfen Capsule as prescribed. Your doctor will advise you on how often you take Tolfen Capsule based on your medical condition. Sometimes, Tolfen Capsule may cause side effects such as nausea, vomiting, heartburn, dizziness, stomach pain, gas, constipation or diarrhoea. Most of these side effects of Tolfen Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to sulphonamides, polmacoxib, aspirin, or other non-steroidal anti-inflammatory drugs, please tell your doctor. Tolfen Capsule is not recommended for pregnant or breastfeeding women. Tolfen Capsule should be used with caution in patients with diabetes, bronchial asthma, high blood pressure, cardiovascular disease, history of oedema, peptic ulcer or gastrointestinal bleeding.

Tolfen Capsule belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is used to reduce pain, stiffness and inflammation caused by osteoarthritis.

• Nausea
• Vomiting
• Heartburn
• Dizziness
• Stomach pain
• Gas
• Constipation
• Diarrhoea

If you are allergic to polmacoxib, aspirin, or other non-steroidal anti-inflammatory drugs, please tell your doctor. Tolfen Capsule is not recommended for pregnant or breastfeeding women. Tolfen Capsule should be used with caution in patients with diabetes, bronchial asthma, high blood pressure, cardiovascular disease, history of oedema, peptic ulcer or gastrointestinal bleeding. Patients with uncontrolled high blood pressure should avoid taking Tolfen Capsule as it may worsen the condition. If you have slurred speech, chest pain, weakness, or shortness of breath while taking Tolfen Capsule , consult a doctor immediately, as these might be symptoms of cardiovascular toxicity. Elderly patients should use Tolfen Capsule with caution as they may be at greater risk for serious gastrointestinal adverse effects such as intestinal or gastric bleeding, perforation and ulceration.

 
Drug-Drug Interaction: Inform your doctor if you are taking blood thinners (warfarin), antifungal (ketoconazole), corticosteroids, immunosuppressants (tacrolimus, cyclosporine), antimetabolite (methotrexate), antimanic agent (lithium), aspirin or other NSAIDs. Tolfen Capsule should be used cautiously in patients taking diuretics (furosemide, thiazide diuretics) or ACE inhibitors (medicines used to lower high blood pressure).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Avoid taking Tolfen Capsule if you have a history of asthma, acute rhinitis, nasal polyps, angioedema, urticaria, have uncontrolled high blood pressure, oedema or fluid retention, liver or kidney impairment, active peptic ulcer or gastrointestinal bleeding, Crohn's disease or ulcerative colitis, congestive heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease, high potassium levels in the blood or blood coagulation disorders.

• WARFARIN
• KETOCONAZOLE
• TACROLIMUS
• CYCLOSPORINE
• METHOTREXATE
• LITHIUM
• ASPIRIN
• FUROSEMIDE

• Maintain a healthy body weight, as obesity may cause joint pains. Do not go for heavy exercise as it may increase your joint pain in arthritis.
• Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscles by lifting light weights.
• Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
• In the chronic conditions of arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids, which help reduce inflammation (redness and swelling).
• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible, and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Besides this, you can use a footrest if required.
   

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation, and tenderness.