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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:39 PM IST
Tazomac 2.25gm Injection is used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. It contains Piperacillin and Tazobactam, which kills bacteria. It may cause side effects such as nausea, constipation, diarrhoea, headache, and trouble sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Tazomac 2.25gm Injection

Tazomac 2.25gm Injection belongs to the 'Antibiotics' class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.

Tazomac 2.25gm Injection contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of 'Penicillin antibiotics.' It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Tazomac 2.25gm Injection, Tazobactam works by preventing bacteria from destroying Piperacillin.

Tazomac 2.25gm Injection will be administered by a healthcare professional. Like all medicines, Tazomac 2.25gm Injection also causes side effects, although not everybody gets them. Common side effects of Tazomac 2.25gm Injection include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly. 

Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits before using Tazomac 2.25gm Injection. Do not use Tazomac 2.25gm Injection while having vaccinations with live bacterial vaccines (typhoid vaccine) since Tazomac 2.25gm Injection may affect vaccines' activity. Tazomac 2.25gm Injection should be used during pregnancy only if the doctor advises you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking Tazomac 2.25gm Injection. 

Uses of Tazomac 2.25gm Injection

Treatment of Bacterial infections, hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and uterine infections.

Medicinal Benefits

Tazomac 2.25gm Injection contains two medicines, namely: Piperacillin and Tazobactam. Piperacillin is a Penicillin antibiotic. It acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme-producing organisms. In Tazomac 2.25gm Injection, Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, Tazomac 2.25gm Injection helps treat various bacterial infections of the stomach, lungs, skin and uterus.

Side Effects of Tazomac 2.25gm Injection

  • Nausea
  • Constipation
  • Diarrhoea
  • Headache
  • Trouble sleeping 

Directions for Use

Tazomac 2.25gm Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, or heart or liver diseases, please inform your doctor before starting Tazomac 2.25gm Injection. Please seek medical advice if you are pregnant or breastfeeding before taking Tazomac 2.25gm Injection. Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Safety and efficacy of Tazomac 2.25gm Injection in children less than two months of age have not been established.

Therapeutic Class

ANTIBIOTIC COMBINATION

Drug-Drug Interactions

verifiedApollotooltip
PiperacillinHeparin
Severe
PiperacillinVancomycin
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, and brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Tazomac 2.25gm Injection properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid intake of alcoholic beverages with Tazomac 2.25gm Injection as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Tazomac 2.25gm Injection in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections. 

Habit Forming

No

What if I have taken an overdose of Tazomac 2.25gm Injection

The overdose of Tazomac 2.25gm Injection is unlikely as it is administered by a doctor. However, in case of overdose, it may cause vomiting, nausea and diarrhoea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - TAZ0006

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