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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:53 PM IST
Sepdic 50mg/10mg Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. It contains Diclofenac and Serratiopeptidase, which works by inhibiting the production od substnaces that cause pain and swelling at the injured or damaged tissue.Also, it helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue. It may cause common side effects like stomach pain, diarrhoea, nausea, and indigestion. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type

ORAL

Return Policy

Not Returnable

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About Sepdic 50mg/10mg Tablet

Sepdic 50mg/10mg Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of diclofenac and serratiopeptidase. Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage of the tooth nerve, infection, decay, extraction, or injury.

Sepdic 50mg/10mg Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Diclofenac works by blocking the action of a chemical messenger known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Serratiopeptidase is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

You can take Sepdic 50mg/10mg Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take Sepdic 50mg/10mg Tablet based on your medical condition. Sepdic 50mg/10mg Tablet may have common side effects like stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Most of these side effects of Sepdic 50mg/10mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Sepdic 50mg/10mg Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. Sepdic 50mg/10mg Tablet may be associated with a small increased risk of heart attack ‘myocardial infarction. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Sepdic 50mg/10mg Tablet

Treatment of Post-traumatic pain, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis.

Medicinal Benefits

Sepdic 50mg/10mg Tablet plays a vital role in reducing pain and inflammation by blocking the release of chemical messengers which cause pain and fever. Sepdic 50mg/10mg Tablet relieves pain and inflammation in arthritic conditions with the benefit of increased antibiotic penetration and micro-circulation at the injury site. Serratiopeptidase present in Sepdic 50mg/10mg Tablet is a proteolytic enzyme which helps in the breakdown of insoluble protein (fibrin) a by-product of blood clots into smaller units. It also causes thinning of the fluids in the body as a result of injury, thereby making fluid drainage smoother in the swollen tissue.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sepdic 50mg/10mg Tablet

  • Stomach ache

  • Diarrhoea

  • Nausea (feeling sick)

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Sepdic 50mg/10mg Tablet as it may lead to an increase in the risk of liver damage. Patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, and hypertension (high blood pressure), should not take Sepdic 50mg/10mg Tablet. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to pain killers and, complications like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Sepdic 50mg/10mg Tablet. Do not drive or operate heavy machinery as intake of Sepdic 50mg/10mg Tablet may cause dizziness. Patients who had recently undergone heart bypass surgery should take Sepdic 50mg/10mg Tablet with caution and only under medical supervision. Use of Sepdic 50mg/10mg Tablet is contraindicated in kidney failure patients or who are undergoing dialysis.

Drug Interactions

Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), anti-cancer (methotrexate), lithium, iodine, and blood clotting agents (warfarin) should not be taken with Sepdic 50mg/10mg Tablet as they can worsen your condition.

Drug-Food Interaction: Drinking alcohol should be avoided while taking Sepdic 50mg/10mg Tablet as it can cause unpleasant effects.

Drug-Disease Interaction: People with peptic ulcer, gastric bleeding, severe heart failure, stroke, ulcerative colitis, Crohn's disease, alcoholism, and high blood pressure should avoid intake of Sepdic 50mg/10mg Tablet. Please seek medical advice.

Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • METHOTREXATE
  • WARFARIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead you can do stretching, low impact aerobic exercise like walking on treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In chronic condition of arthritis or joint pain try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that minimize level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit little as possible, and only for short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a foot rest if required.

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone, or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis, and dental pain due to damage to the tooth nerve, infection, decay, extraction, or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains, or trauma or post-surgery may require a prolonged amount of time to heal. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation are caused due to sprains, strains, trauma or post-surgery. These types of injuries may require a prolonged amount of time to heal.

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Alcohol

Caution

You are recommended not to consume alcohol along with Sepdic 50mg/10mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant before taking Sepdic 50mg/10mg Tablet.

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Breast Feeding

Caution

Sepdic 50mg/10mg Tablet may pass into the breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

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Driving

Caution

Sepdic 50mg/10mg Tablet may affect driving as it causes dizziness. Drive or operate machinery only when you are alert.

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Liver

Caution

Sepdic 50mg/10mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Sepdic 50mg/10mg Tablet to be taken with caution if you have a history of kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Caution

Sepdic 50mg/10mg Tablet is not recommended for children under 10 years of age. For them dose has to be adjusted and recommended by a child specialist only.

Country of origin

India
Other Info - SE88998

Author Details

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FAQs

Sepdic 50mg/10mg Tablet is used in the treatment of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain.
Sepdic 50mg/10mg Tablet when taken by patients who are allergic to pain-killers can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.
You should only take Sepdic 50mg/10mg Tablet if doctor has prescribed you. The maximum recommended dose of Sepdic 50mg/10mg Tablet is twice daily. Sepdic 50mg/10mg Tablet can be one in the morning and one in the evening.
Rheutamoid arthritis is an autoimmune disease that causes chronic inflammation and pain of the joints.
Ankylosing spondylitis is a arthritis of the spine which can lead to the fusion of the vertebrae, lead to pain and inflammation in the spine.
Yes, Sepdic 50mg/10mg Tablet can cause stomach upset. So, it should be preferably taken with food to avoid it.
Sepdic 50mg/10mg Tablet should be stored in a cool and dry place, away from direct sunlight. Keep the medicine out of reach of children.
Sepdic 50mg/10mg Tablet is generally safe when used as directed by your doctor for short-term pain and inflammation relief. However, you should not use Sepdic 50mg/10mg Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, hypertension (high blood pressure), kidney failure, or if you are undergoing dialysis.
Yes, you can stop taking Sepdic 50mg/10mg Tablet once your pain is relieved, but only after consulting your doctor. It is recommended to follow your doctor's advice on the duration and dosage of Sepdic 50mg/10mg Tablet, as stopping the medication too early could affect your recovery.
Yes, the use of Sepdic 50mg/10mg Tablet can cause nausea and vomiting as side effects. Taking it with food may help prevent nausea. If you experience vomiting, try drinking small sips of water or other fluids frequently. If these symptoms persist, please consult your doctor.
Yes, the use of Sepdic 50mg/10mg Tablet may cause dizziness as a side effect in some individuals. Avoid driving or operating machinery if you experience dizziness. If dizziness persists, please consult your doctor.
Yes, Sepdic 50mg/10mg Tablet is contraindicated in patients who are allergic to any of its components, those with kidney failure, or those undergoing dialysis. It should not be taken by patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure). Also, it should be avoided during the last trimester of pregnancy. Please consult your doctor if you have any concerns while using Sepdic 50mg/10mg Tablet.
No, Sepdic 50mg/10mg Tablet is not generally recommended for stomach pain. In fact, it may cause stomach upset, ulcers, or bleeding. If you have stomach pain, please consult your doctor for a proper diagnosis and treatment.
Yes, long-term or high-dose use of Sepdic 50mg/10mg Tablet, a nonsteroidal anti-inflammatory drug (NSAID), can potentially damage the kidneys. Regular monitoring and caution are advised when using Sepdic 50mg/10mg Tablet, especially in individuals with existing kidney disease. Please consult your doctor before using Sepdic 50mg/10mg Tablet.
Yes, Sepdic 50mg/10mg Tablet can be taken on an empty stomach, but it is generally advisable to take Sepdic 50mg/10mg Tablet with food to reduce the risk of side effects. Always follow your doctor's instructions when taking Sepdic 50mg/10mg Tablet.
Sepdic 50mg/10mg Tablet is generally not recommended for children under 10 years of age unless prescribed by a doctor. Always consult a paediatrician before giving Sepdic 50mg/10mg Tablet to a child, as the dosage may need to be adjusted for them.
Sepdic 50mg/10mg Tablet is intended for short-term use only, as it may potentially cause side effects such as gastrointestinal or cardiovascular issues. Always follow your doctor's advice regarding the duration and dosage.
No, it is generally not recommended to consume alcohol while taking Sepdic 50mg/10mg Tablet as it may increase the risk of side effects, such as stomach irritation, ulcers, and bleeding. Your doctor may advise you to limit or avoid alcohol consumption while taking Sepdic 50mg/10mg Tablet.

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