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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 9:32 AM IST

Selepeg 400 Tablet is used to treat pulmonary arterial hypertension (high blood pressure in the lungs), slow down the worsening of symptoms, and reduce the chance of hospitalisation. It contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries, lowering the pressure in them.

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Composition :

SELEXIPAG-400MCG

Manufacturer/Marketer :

Msn Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Selepeg 400 Tablet

Selepeg 400 Tablet belongs to the group of medicines called selective non-prostanoid IP prostacyclin receptor agonists used to treat pulmonary arterial hypertension (high blood pressure in the lungs), to slow down the worsening of symptoms and to reduce the chance of hospitalisation.

Selepeg 400 Tablet contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries. Thereby, it lowers the pressure in the pulmonary arteries.

In some cases, Selepeg 400 Tablet may cause side effects such as headache, nausea, vomiting, diarrhoea, and stuffy nose. Most of these side effects may not require medical attention and resolve gradually over time. However, if the side effects persist or worsen, consult the doctor.

Do not take Selepeg 400 Tablet if you are pregnant or breastfeeding. Selepeg 400 Tablet is not recommended for use in children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of Selepeg 400 Tablet

Treatment of Pulmonary arterial hypertension (PAH)

Medicinal Benefits

Selepeg 400 Tablet belongs to the group of medicines called selective non-prostanoid IP prostacyclin receptor agonists used to treat pulmonary arterial hypertension (high blood pressure in the lungs), delay disease progression and lower the risk of hospitalisation for pulmonary arterial hypertension. Selepeg 400 Tablet contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries. Thereby, Selepeg 400 Tablet lowers the pressure in the pulmonary arteries, relieves symptoms of pulmonary arterial hypertension and slows down its progression.

Side Effects of Selepeg 400 Tablet

  • Headache
  • Flushing (reddening of the face)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Nasopharyngitis (stuffed nose)
  • Jaw pain, joint pain, muscle pain, leg pain

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Selepeg 400 Tablet if you are allergic to any of its components, if you have/had heart problems such as unstable angina, severe coronary heart disease, heart attack within last six months, weak heart, severe irregular heartbeat, defect of heart valves, or if you had a stroke within the last three months, reduced blood supply to the brain, or if you are taking gemfibrozil. Inform the doctor if you have low blood pressure associated with dizziness, severe diarrhoea or vomiting, thyroid problems, severe kidney problems, undergoing dialysis, severe liver problems, or if you are taking medicines for high blood pressure. Do not take Selepeg 400 Tablet if you are pregnant or breastfeeding. Selepeg 400 Tablet is not recommended for children. Let the doctor know if you are taking any other medicines, including supplements or herbal products.

Therapeutic Class

MISCELLANEOUS

Drug-Drug Interactions

verifiedApollotooltip
SelexipagClopidogrel
Critical
SelexipagGemfibrozil
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Lower your intake of salt. This helps in reducing the risk of developing oedema.
  • Include vegetables, fruits, whole grains, lean meats, poultry, fish, and fat-free/low-fat dairy products in your diet.
  • Avoid canned foods, processed foods, pickled, and frozen foods. Instead, consume fresh foods.
  • Limit consumption of caffeine and alcohol as they can alter blood pressure.
  • Monitor fluid intake to prevent swelling/fluid retention.

Habit Forming

No

How Selepeg 400 Tablet Works

Selepeg 400 Tablet contains Selexipag, which works by widening the pulmonary arteries and reducing their hardening. This makes it easier for the heart to pump blood through the pulmonary arteries. Thereby, it lowers the pressure in the pulmonary arteries.

What if I have taken an overdose of Selepeg 400 Tablet

Do not take more than prescribed dose. Using more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you may have overdosed of Selepeg 400 Tablet , please go to the emergency department of the closest hospital or nursing home.
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Alcohol

Consult your doctor

It is not known whether Selepeg 400 Tablet interacts with alcohol. Please consult your doctor.

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Pregnancy

Unsafe

Selepeg 400 Tablet is not recommended during pregnancy. Consult the doctor if you become pregnant during treatment with Selepeg 400 Tablet .

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Breast Feeding

Unsafe

It is not known if Selexipag passes into breast milk. Selepeg 400 Tablet is not recommended during lactation.

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Driving

Caution

Selepeg 400 Tablet may cause headaches and low blood pressure, affecting your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

Selepeg 400 Tablet is not recommended for patients with severe liver impairment. Dose adjustment may be needed in people with moderate hepatic impairment. Consult the doctor if you have liver problems.

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Kidney

Caution

Please consult the doctor if you have any concerns regarding the usage of Selepeg 400 Tablet in patients with kidney impairment.

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Children

Unsafe

Selepeg 400 Tablet is not recommended for use in children below 18 years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Msn Laboratories Pvt.Ltd., Msn House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad - 18 Telangana, India
Other Info - SEL0135

Author Details

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FAQs

Selepeg 400 Tablet is used to treat Pulmonary arterial hypertension (PAH).
Selepeg 400 Tablet relaxes the blood vessels in the lungs and allows the blood to flow easily. Thereby, it relieves the symptoms of pulmonary arterial hypertension and slows down its progression.
Do not stop taking Selepeg 400 Tablet on your own. Selepeg 400 Tablet helps control the symptoms of PAH but does not cure it. Therefore, continue taking Selepeg 400 Tablet for as long as it has been prescribed by the doctor.
Selepeg 400 Tablet should be used with caution in patients older than 75 years as there is limited experience in this age group. Consult the doctor if you have any concerns.
Let the doctor know if you are taking gemfibrozil, a medicine used to lower fat levels in the blood. If you are taking gemfibrozil, your doctor may tell you not to take Selepeg 400 Tablet .

Disclaimer

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