apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Sam MB 10mg Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy. It contains Methylene Blue, which works by converting methemoglobin to a more efficient type of haemoglobin to better carry oxygen throughout the body. Common side effects of this medication are mild to moderate pain at the site of injection, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm.

Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Synonym

METHYLTHIONINIUM CHLORIDE

Manufacturer/Marketer

Samarth Life Sciences Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Sam MB 10mg Injection

Sam MB 10mg Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy. Methemoglobinemia is a condition that occurs when the blood cannot deliver oxygen where it is needed in the body. Vasodilatory shock is a medical emergency in which your body cannot get enough blood to your heart, brain, and kidneys.

Sam MB 10mg Injection contains Methylene Blue. Methylene blue works by converting methemoglobin to a more efficient type of haemoglobin to better carry oxygen throughout the body.

A qualified healthcare professional will administer Sam MB 10mg Injection. You may experience mild to moderate pain at the site of injection, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm. Most of these side effects of Sam MB 10mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, contact your doctor.

If you have a glucose-6-phosphate dehydrogenase (G6PD) deficiency, you should avoid using methylene blue. Many medicines, particularly antidepressants, can interact with methylene blue. So, before taking the Sam MB 10mg Injection, inform your doctor about all of your medical issues, sensitivities, and drugs. Also, let your doctor know if you are pregnant, planning to become pregnant, or are breastfeeding.

Uses of Sam MB 10mg Injection

Treatment of Methemoglobinemia and Vasodilatory shock

Medicinal Benefits

Sam MB 10mg Injection contains Methylene Blue, which belongs to the class of monoamine oxidase inhibitors. It is used to treat a condition called methemoglobinemia. Methylene blue converts methemoglobin into a more efficient type of haemoglobin to better carry oxygen throughout the body.

Directions for Use

A qualified healthcare professional will administer Sam MB 10mg Injection. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sam MB 10mg Injection

  • Mild to moderate pain at the site of injection
  • Pain in your arms or legs
  • Blue or green urine
  • Altered sense of taste
  • Headache
  • Dizziness
  • Sweating
  • Skin discoloration
  • Nausea
  • Feeling warm

Drug Warnings

It is recommended not to use it if you are allergic to methylene blue or other ingredients. Methylene blue should not be used to treat methemoglobinemia in people with glucose-6-phosphate deficiencies (G-6-PD). When methylene blue was delivered intravenously to patients who were concurrently taking other medications having serotonin reuptake inhibitor characteristics, serotonin toxicity/serotonin syndrome was reported. If drugs with serotonin reuptake inhibition capabilities are being used, they must be stopped before using methylene blue injectables to allow for a washout time of at least 4 - 5 half-lives. So, before taking the Sam MB 10mg Injection, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.

Drug Interactions

Drug-Drug Interactions: Sam MB 10mg Injection may interact with antidepressant medications (e.g. escitalopram), amino acids (e.g. 5-hydroxytryptophan), and certain central nervous system stimulant medications (e.g. amphetamine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Sam MB 10mg Injection may interact with disease conditions, including glucose-6-phosphate deficiencies (G-6-PD) and renal dysfunction.

Drug-Drug Interactions Checker List

  • ESCITALOPRAM
  • 5 HYDROXYTRYPTOPHAN
  • AMPHETAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Adhering to a regular meal pattern, minimizing intake of insoluble fibers, alcohol, caffeine, spicy foods, and fat, as well as engaging in regular physical activity and being hydrated, are all standard suggestions.
  • Keep a diet or food diary.
  • Make time to eat. If possible, sit down, relax, and enjoy your meal with others. Avoid eating while on the go!
  • Eat three regular meals a day, at nearly the same times and in roughly the same amounts.
  • Maintain an active lifestyle and get enough exercise. This will make you feel better.
  • Avoid high-fat meals and limit your intake of poorly absorbed carbs.
  • Maintain a balanced lifestyle and try to reduce stress as much as possible. Allow yourself time to relax and do things you enjoy. 
  • Avoid drinking alcohol and quit smoking.

Special Advise

  • Recommended to monitor haemoglobin and methemoglobin levels.

Disease/Condition Glossary

Methemoglobinemia: Methemoglobinemia is a condition that occurs when the blood cannot deliver oxygen where it is needed in the body.

Vasodilatory shock: Vasodilatory shock, also known as Distributive shock. It is a medical emergency in which your body cannot get enough blood to your heart, brain, and kidneys. This occurs when your blood vessels are highly dilated (flaccid or relaxed), lowering your blood pressure and reducing the amount of blood that can reach your organs.

bannner image

Alcohol

Caution

It is not known whether Sam MB 10mg Injection interacts with alcohol. However, as a precautionary measure, it is advisable not to take or limit alcohol.

bannner image

Pregnancy

Caution

Inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Sam MB 10mg Injection.

bannner image

Breast Feeding

Caution

Let your doctor know if you are a nursing mother before taking Sam MB 10mg Injection; your doctor may suggest stopping breastfeeding for a certain period.

bannner image

Driving

Safe if prescribed

Sam MB 10mg Injection usually does not affect your ability to drive or operate machinery.

bannner image

Liver

Caution

Limited information was available about using Sam MB 10mg Injection in patients with liver disease. Inform your doctor before receiving Sam MB 10mg Injection if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Use with caution in patients with kidney failure, as methylene blue is primarily excreted through the kidneys. Inform your doctor before receiving Sam MB 10mg Injection if you have a history of kidney diseases. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Safe if prescribed

Please consult your doctor. Your doctor will prescribe this medicine based on your child's condition.

Country of origin

India

Manufacturer/Marketer address

C-122,,Delhi Road,Yamuna Puram, Bulandshahr-203001, Uttar Pradesh, India
Other Info - SA75515

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Sam MB 10mg Injection is used to treat a condition called methemoglobinemia. Besides this, it can be used to treat vasodilatory shock unresponsive to conventional therapy.
Sam MB 10mg Injection contains Methylene Blue. Methylene blue converts methemoglobin into a more efficient type of haemoglobin to better carry oxygen throughout the body. Thus, it efficiently treats a condition called methemoglobinemia.
Injection site reactions, pain in your arms or legs, blue or green urine, altered sense of taste, headache, dizziness, sweating, skin discolouration, nausea, and feeling warm are the common side effects of Sam MB 10mg Injection.
If you are currently taking anti-depressant medications such as escitalopram, notify your doctor before receiving methylene blue. Combining these medications can increase the risk of an uncommon but deadly disease known as serotonin syndrome, which can cause symptoms such as confusion, hallucination, seizure, dramatic fluctuations in blood pressure, rapid heart rate, and fever.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.