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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:37 PM IST
RPIGAT 2.5 TABLETS is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. It contains Rivaroxaban, which works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation. You may experience bleeding, anemia (low number of red blood cells), and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Natco Pharma Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About RPIGAT 2.5 TABLETS

RPIGAT 2.5 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 2.5 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs.

RPIGAT 2.5 TABLETS contains Rivaroxaban, a blood thinner that works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Take RPIGAT 2.5 TABLETS as prescribed. You are advised to take RPIGAT 2.5 TABLETS for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience bleeding, anemia (low number of red blood cells), and nausea. Most of these side effects of RPIGAT 2.5 TABLETS do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are known to be allergic to RPIGAT 2.5 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 2.5 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 2.5 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Uses of RPIGAT 2.5 TABLETS

Prevention of blood clot

Medicinal Benefits

RPIGAT 2.5 TABLETS belongs to a class of drugs known as anticoagulants or blood thinner. RPIGAT 2.5 TABLETS is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation. RPIGAT 2.5 TABLETS works by inhibiting the production of clotting factors by decreasing the action of vitamin K. This prevents the conversion of fibrinogen (soluble protein) to fibrin (insoluble protein), thereby preventing blood clots formation.

Directions for Use

Take RPIGAT 2.5 TABLETS with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RPIGAT 2.5 TABLETS

  • Bleeding

  • Anaemia (low number of red blood cells)

  • Nausea

Drug Warnings

RPIGAT 2.5 TABLETS should be used with caution in children. Prolonged use of RPIGAT 2.5 TABLETS may cause hair loss. Regular blood tests are recommended while taking RPIGAT 2.5 TABLETS to check the time taken for your blood to clot and the level of platelets (blood cells). If you are known to be allergic to RPIGAT 2.5 TABLETS or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using RPIGAT 2.5 TABLETS . If you have a stomach ulcer, kidney or liver problems, high blood pressure, or bleeding problems, inform your doctor before taking RPIGAT 2.5 TABLETS . Talk to your doctor immediately if you are pregnant or breastfeeding.

Drug Interactions

Drug-Drug Interactions: RPIGAT 2.5 TABLETS may interact with antiplatelet drugs (warfarin, enoxaparin), antiviral or HIV medicines (lopinavir, ritonavir), painkillers (aspirin, ibuprofen), antiepileptic drugs (carbamazepine, phenytoin), drugs to treat fungal or bacterial infections (fluconazole, erythromycin, clarithromycin), and herbal medication for depression (St John's wort).

Drug-Food Interactions: RPIGAT 2.5 TABLETS may interact with grapefruit juice, cranberry juice, and green tea. 

Drug-Disease Interactions: Use with caution in patients with kidney, liver, or bleeding problems, heart problems, and unstable blood pressure.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ENOXAPARIN
  • LOPINAVIR
  • RITONAVIR
  • ASPIRIN
  • IBUPROFEN
  • CARBAMAZEPINE
  • PHENYTOIN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • FLUCONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid making any changes in your diet without first talking to your doctor.

  • Cranberry juice, grapefruit juice, noni juice, and pomegranate juice may interact with RPIGAT 2.5 TABLETS and lead to unwanted side effects. Hence try to avoid these juices while taking RPIGAT 2.5 TABLETS .

  • Avoid drinking alcohol as it increases the risk of gastrointestinal ulcer/bleeding.

Special Advise

You should have regular platelet count, factor V assay, fibrinogen level test, prothrombin time test (PT or PT-INR) and the INR, or international normalized ratio to analyze your blood clotting time.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling. Pulmonary embolism (blood clots in the lung) is a chronic condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include cough, chest pain, and shortness of breath.

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Alcohol

Unsafe

You are recommended to avoid consumption of alcohol with RPIGAT 2.5 TABLETS as it may increase the risk of bleeding.

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Pregnancy

Caution

Tell your doctor before using RPIGAT 2.5 TABLETS because it may cause harmful effects. So, only use in that condition when a doctor is prescribed.

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Breast Feeding

Caution

RPIGAT 2.5 TABLETS may pass into breast milk. Therefore consult your doctor.

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Driving

Safe if prescribed

RPIGAT 2.5 TABLETS usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take RPIGAT 2.5 TABLETS with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take RPIGAT 2.5 TABLETS with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

RPIGAT 2.5 TABLETS is not approved for children. Therefore RPIGAT 2.5 TABLETS is not safe for children.

Country of origin

India

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - RPI0004

FAQs

RPIGAT 2.5 TABLETS is used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lung) by reducing blood clot formation.
No, you are not recommended to stop taking RPIGAT 2.5 TABLETS without consulting your doctor to worsen the condition. Therefore, take RPIGAT 2.5 TABLETS for as long as your doctor has prescribed it.
No, RPIGAT 2.5 TABLETS is not expected to cause weight gain. If you notice unexpected weight gain and think it is because of this RPIGAT 2.5 TABLETS , immediately consult your doctor and inform him about it.
RPIGAT 2.5 TABLETS has many beneficial effects, but it has the ability to make you bleed more than normal. Even with minor injuries as it decreases your ability to blood clotting. Sometimes RPIGAT 2.5 TABLETS may cause severe bleeding that may be dangerous and may require urgent medical care. This risk may be increased in people taking RPIGAT 2.5 TABLETS along with other blood thinner medicines.
Avoid taking grapefruit and grapefruit juice while taking RPIGAT 2.5 TABLETS , and it contains compounds that slow down the metabolism of RPIGAT 2.5 TABLETS and increase the activity leading to bleeding.
It is not known that RPIGAT 2.5 TABLETS causes hair loss. Kindly contact your doctor.
RPIGAT 2.5 TABLETS is a type of medicine known as an anticoagulant. RPIGAT 2.5 TABLETS works by stopping a clotting factor called factor Xa from working. This thins your blood, so it takes longer to clot.
You should take RPIGAT 2.5 TABLETS just after a meal or snack, or as advised by the doctor. It is important to take it with food to help your body absorb the entire dose.
The side effects of RPIGAT 2.5 TABLETS include bleeding, nausea and anemia (lack of blood). If these side effects persist or worsen, please consult your doctor.
Yes, RPIGAT 2.5 TABLETS is a blood thinner. It prevents the blood from clotting inside the blood vessels and also prevents the blood clots from recurring in the blood vessels.
Avoid taking grapefruit and grapefruit juice while taking RPIGAT 2.5 TABLETS as grapefruit contains compounds that slow down the RPIGAT 2.5 TABLETS metabolism and increase the activity leading to bleeding. However, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the vitamin K activity or increases the blood clotting such as brussels, spinach, sprouts, broccoli, mustard greens, asparagus and green tea. But, the use of these food items is not restricted with RPIGAT 2.5 TABLETS .

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