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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 30, 2024 | 3:20 PM IST
Remdiz 100 mg Injection is used to treat coronavirus disease requiring hospitalisation. It contains Remdesivir, which works by inhibiting an enzyme that helps the coronavirus to replicate itself. In some cases, this medicine may cause side effects such as nausea, increased transaminase levels, and increased prothrombin time. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition

REMDESIVIR-100MG

Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Remdiz 100 mg Injection

Remdiz 100 mg Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation. Coronavirus disease, also known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2), is an infectious disease caused by the corona virus.
 
Remdiz 100 mg Injection contains ‘Remdesivir, which binds to the viral-RNA dependant RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Remdiz 100 mg Injection lowers the virus load in the body and helps treat the infection.
 
Remdiz 100 mg Injection will be administered by a healthcare professional in a hospital or a healthcare setting capable of providing in-patient hospital care. In some cases, you may experience certain side effects such as nausea, increased transaminase levels, and increased prothrombin time. You are advised to talk to your doctor if you experience these side effects persistently. 
 
Consult your doctor if you are pregnant, think you are pregnant or breastfeeding. Transaminase levels should be monitored before and during the treatment with Remdiz 100 mg Injection. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Remdiz 100 mg Injection

Treatment of Coronavirus disease (COVID 19)

Medicinal Benefits

Remdiz 100 mg Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor. Remdiz 100 mg Injection is used to treat corona virus disease requiring hospitalisation. Remdiz 100 mg Injection binds to the viral-RNA-dependant RNA polymerase enzyme, an enzyme that helps the corona virus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Remdiz 100 mg Injection lowers virus load in the body and helps treat the infection.

Directions for Use

Remdiz 100 mg Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Remdiz 100 mg Injection

  • Nausea
  • Increased transaminase levels
  • Increased prothrombin time

Drug Warnings

Do not take Remdiz 100 mg Injection if you are allergic to any of its contents. Inform your doctor if you have heart, liver or kidney problems. Consult your doctor before taking Remdiz 100 mg Injection if you are pregnant, think you are pregnant or breastfeeding. Remdiz 100 mg Injection is indicated for use only in patients above 12 years, weighing at least 40kg. Transaminase levels should be monitored before and during the treatment with Remdiz 100 mg Injection. Treatment with Remdiz 100 mg Injection should be discontinued if the ALT (Alanine aminotransferase) levels are greater than ten times the upper limit of normal. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Drug Interactions

Drug-Drug Interactions: Remdiz 100 mg Injection may interact with antimalarials (chloroquine, hydroxychloroquine)

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interaction: Inform your doctor if you are at an increased risk of transaminase elevations and infusion-related reactions.

Drug-Drug Interactions Checker List

  • CHLOROQUINE
  • HYDROXYCHLOROQUINE

Habit Forming

No

Diet & Lifestyle Advise

  • Always remember to wear a mask when you are around other people. Wearing a mask helps in preventing the spread of infection.
  • Maintain social distance and avoid gatherings.
  • Clean your hands regularly with soap and water or an alcohol-based sanitiser.
  • Clean and disinfect surfaces regularly.
  • Drink plenty of fluids. Stay well hydrated.
  • Saltwater gargling and steam inhalation would be helpful.
  • Exercise regularly. Try walking for 10 minutes in the morning, afternoon, evening and night.
  • Consume protein-rich foods.

Special Advise

  • Regular monitoring of transaminase levels, liver and kidney function before and during the treatment is advised.

Disease/Condition Glossary

COVID-19: Corona virus disease, also known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) is an infectious disease caused by the corona virus. Corona virus belongs to a group of RNA viruses and has crown-like projections on the surface of the pathogen. The virus transmits through droplets generated from an infectious person’s cough, sneeze or heavy breathing. The common symptoms of corona virus disease are dry cough, breathlessness, shortness of breath, tiredness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache and sore throat.

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Alcohol

Caution

It is not known whether Remdiz 100 mg Injection interacts with alcohol. Please consult your doctor.

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Pregnancy

Caution

There is insufficient data regarding the safety of Remdiz 100 mg Injection during pregnancy. Please consult a doctor if you are pregnant or think you might be pregnant.

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Breast Feeding

Caution

There is insufficient data regarding the passage of Remdiz 100 mg Injection into breastmilk. Please consult a doctor if you are breastfeeding.

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Driving

Caution

It is unknown if Remdiz 100 mg Injection affects your ability to drive. Drive or operate machinery only if you are alert.

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Liver

Caution

The effectiveness of Remdiz 100 mg Injection in patients with liver impairment have not been evaluated. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

The effectiveness of Remdiz 100 mg Injection in patients with kidney impairment have not been evaluated. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Please consult your doctor if you have any concerns regarding the usage of Remdiz 100 mg Injection in children.

Country of origin

INDIA

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - REM0183

Author Details

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FAQs

Remdiz 100 mg Injection binds to the RNA polymerase enzyme, an enzyme that helps the coronavirus to replicate itself. This inhibits viral replication by premature termination of RNA transcription. Thereby, Remdiz 100 mg Injection lowers the virus load in the body and helps treat the infection.
Remdiz 100 mg Injection should not be taken along with chloroquine phosphate and hydroxychloroquine sulphate as it might cause reduced anti-viral activity of Remdiz 100 mg Injection. Co-administration of these drugs is not recommended.
No, Remdiz 100 mg Injection is not indicated for the prevention of coronavirus disease. Remdiz 100 mg Injection has been approved by DCGI (Drug Control General of India) for emergency use only in patients who are COVID-positive.
Regularly clean your hands thoroughly using soap and water or an alcohol-based sanitiser. Avoid touching your nose, eyes, and mouth without washing your hands. Clean and disinfect surfaces regularly. Always remember to wear a mask, maintain social distance and avoid gatherings.
Covid-19 spreads through respiratory droplets when in close or direct contact with an infected person. The virus can spread through an infected person’s sneeze or cough. The virus can also be transmitted by touching any contaminated surfaces and then touching the nose, mouth or eyes without washing the hands.
Remdiz 100 mg Injection belongs to a group of anti-viral medicines called SARS-CoV-2 nucleotide analogue RNA polymerase inhibitor used to treat coronavirus disease requiring hospitalisation.
Inform your doctor, if you are allergic to any of its contents. If you have heart, liver or kidney problems or if you are using any other medications. And also let your doctor know if you are breastfeeding, pregnancy or planning pregnancy before starting Remdiz 100 mg Injection to avoid possible interactions.
Not every patient with COVID-19 requires Remdiz 100 mg Injection. It is specifically recommended for adults and children hospitalized with severe COVID-19 who require oxygen therapy or are on a ventilator. However, always consult your doctor for personalized medical advice.
COVID-19 is a respiratory illness caused by the SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus 2) virus. The common symptoms of corona virus disease are dry cough, breathlessness, shortness of breath, tiredness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache and sore throat.
An Emergency Use Authorization (EUA) is a mechanism used by the U.S. food and drug administration (FDA) to expedite the availability and use of medical products, such as drugs and vaccines, during public health emergencies. EUA's are typically issued during situations like the COVID-19 pandemic to quickly provide access to critical medical countermeasures.
Remdiz 100 mg Injection is administered intravenously (IV), by a healthcare professional in a hospital or healthcare setting. Do not self-administer.
Remdiz 100 mg Injection is used to treat hospitalized patients who are suffering with severe COVID-19.
The common side effects of Remdiz 100 mg Injection are nausea, increased transaminase levels and increased prothrombin time. If any of these side effects persist or worsen, please consult your doctor.
Yes, Remdiz 100 mg Injection is generally considered safe when used under the supervision of a healthcare professional. However, like all medications, it can have side effects. So it's important to monitor for any adverse reactions and inform your doctor if you any side effects persist or worsen.
A pregnant women infected with covid-19 should take the advice of a doctor as there is limited data on the safety of Remdiz 100 mg Injection during pregnancy.
If you are suffering from diabetes and high blood pressure, you should take your doctor’s advice before taking Remdiz 100 mg Injection.
Remdiz 100 mg Injection should only be administered to those with laboratory-confirmed COVID-19 infection to ensure its appropriate use and effectiveness. However, consult your doctor, if you are highly suspected with COVID -19 symptoms.

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