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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 22, 2024 | 7:36 PM IST
Prucalshil-1 Disintegrating Strips is used to treat chronic idiopathic constipation. It contains prucalopride, which acts on the muscle walls of the gut, increases bowel motility and helps restore the normal functioning of the bowel. In some cases, this medicine may cause side effects, such as headache, diarrhoea, nausea, and abdominal pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Composition

PRUCALOPRIDE-1MG

Manufacturer/Marketer

Shilpa Medicare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Prucalshil-1 Disintegrating Strips

Prucalshil-1 Disintegrating Strips is used to treat chronic idiopathic constipation. Chronic idiopathic constipation is a functional bowel disorder characterised by difficult or incomplete and/or infrequent passage of stools that lasts for 3months or longer and is not caused by any disease or medication. 
 
Prucalshil-1 Disintegrating Strips contains ‘prucalopride’, which acts on the muscle walls of the gut, and increases bowel motility. Thereby, helps restore the normal functioning of the bowel and treats constipation. Prucalshil-1 Disintegrating Strips helps treat chronic constipation in adults in whom laxatives do not work well. 
 
You are advised to take Prucalshil-1 Disintegrating Strips for as long as your doctor has prescribed it to you. In some cases, you may experience certain common side effects, such as headache, diarrhoea, nausea, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Avoid taking Prucalshil-1 Disintegrating Strips if you are pregnant or breastfeeding. Prucalshil-1 Disintegrating Strips is not recommended for children below 18 years as safety and effectiveness have not been established. Prucalshil-1 Disintegrating Strips may cause dizziness and tiredness, so drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to rule out any unpleasant side effects or interactions.

Uses of Prucalshil-1 Disintegrating Strips

Treatment of Chronic idiopathic constipation

Medicinal Benefits

Prucalshil-1 Disintegrating Strips belongs to the group of medicines called gastrointestinal prokinetics used to treat chronic idiopathic constipation. Prucalshil-1 Disintegrating Strips acts on the muscle walls of the gut and increases bowel motility. Thus, helps restore the normal functioning of the bowel and treats constipation. Prucalshil-1 Disintegrating Strips helps treat chronic constipation in adults in whom laxatives do not work well. 

Directions for Use

Swallow Prucalshil-1 Disintegrating Strips as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Prucalshil-1 Disintegrating Strips

  • Abdominal pain/cramps
  • Headache
  • Diarrhoea
  • Vomiting
  • Tiredness
  • Nausea

Drug Warnings

Do not take Prucalshil-1 Disintegrating Strips if you are allergic to any of its components, if you are on renal dialysis, have perforation/obstruction of the gut wall, inflammation of the intestinal tract, Crohn’s disease, toxic megacolon/megarectum or ulcerative colitis. Inform your doctor if you have AIDS, hormonal problems, neurological disease, suicidal tendency, mood disorder, cancer, heart, kidney or liver problems. Avoid taking Prucalshil-1 Disintegrating Strips if you are pregnant or breastfeeding. Prucalshil-1 Disintegrating Strips is not recommended for children below 18 years as safety and effectiveness have not been established. Prucalshil-1 Disintegrating Strips may cause dizziness and tiredness, so drive only if you are alert.

Drug Interactions

Drug-Drug Interactions: Prucalshil-1 Disintegrating Strips may interact with an antihistamine (diphenhydramine).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have renal dialysis, perforation/obstruction of the gut wall, inflammation of the intestinal tract, Crohn’s disease, toxic megacolon/megarectum, ulcerative colitis, mood disorders, or suicidal tendency.

Drug-Drug Interactions Checker List

  • DIPHENHYDRAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try maintaining a balanced diet that includes fresh fruits and vegetables.

  • Stay hydrated, drink enough water and fluids.

  • Exercise regularly, and stay fit.

  • Get enough sleep.

  • Try making time to empty your bowels whenever the body tells you to.

  • Eat food rich in fibre such as whole-wheat bread, oatmeal, flaxseed, nuts, beans, lentils, fruits (berries, apples, oranges, bananas, pears, figs) and vegetables (broccoli, spinach, sweet potatoes, avocados).

Disease/Condition Glossary

Chronic idiopathic constipation: Chronic idiopathic constipation is a functional bowel disorder characterised by difficult or incomplete and/or infrequent passage of stools that lasts for 3months or longer and is not caused by any disease or medication. Symptoms include bloating, abdominal pain, and feeling as if the bowel movement is incomplete. Constipation occurs when the normal muscle contractions in the large intestine slow down, which causes the incomplete elimination of the bowel from the body. Constipation could be associated with a sudden change of diet, a diet with less fibre, not drinking enough liquids, lack of exercise, loss of tone of the bowel muscles in older people, or having to stay in bed for a longer duration.

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Alcohol

Caution

It is not known if alcohol interacts with Prucalshil-1 Disintegrating Strips . Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Unsafe

Prucalshil-1 Disintegrating Strips is not recommended during pregnancy. Use a reliable method of contraception while taking Prucalshil-1 Disintegrating Strips . Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Prucalshil-1 Disintegrating Strips might pass into breastmilk. Avoid breastfeeding while taking Prucalshil-1 Disintegrating Strips .

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Driving

Caution

Prucalshil-1 Disintegrating Strips is unlikely to affect your ability to drive. However, sometimes Prucalshil-1 Disintegrating Strips might cause dizziness and tiredness, so drive only if you are alert.

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Liver

Caution

Please consult your doctor if you have liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor if you have kidney impairment/kidney disease.

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Children

Unsafe

Prucalshil-1 Disintegrating Strips is not recommended for children below 18 years as safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

12-6-214/A1, Hyderabad Road, Raichur 584 135, Karnataka, India.
Other Info - PRU0096

Author Details

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FAQs

Prucalshil-1 Disintegrating Strips is used to treat chronic idiopathic constipation.
Prucalshil-1 Disintegrating Strips acts on the muscle walls of the gut and increases bowel motility. Thereby, helps restore the normal functioning of the bowel and treats constipation.
Diarrhoea might occur if Prucalshil-1 Disintegrating Strips is taken in larger doses. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. Contraceptive pills might become ineffective in case of severe diarrhoea. In such conditions, use an extra method of contraception.
Do not take Prucalshil-1 Disintegrating Strips for longer durations unless advised by the doctor as it might lead to dependency on Prucalshil-1 Disintegrating Strips for a bowel movement. Consult your doctor if your bowel movement is irregular even after taking Prucalshil-1 Disintegrating Strips for four weeks.
Drink plenty of fluids and consume fibre-rich food, whole-grain bread, unprocessed bran, fruits and vegetables. Try to exercise regularly.
If you miss a dose, try to take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid taking the double dose as it might cause unpleasant side effects or overdose.
Prucalshil-1 Disintegrating Strips may cause side effects such as vomiting, nausea, diarrhoea, headache, tiredness and stomach cramps/pain. If these side effects persist or worsen, please consult your doctor.
Prucalshil-1 Disintegrating Strips has been shown to act quickly but the effect varies from person to person. This is because each patient reacts differently to particular medication. Generally, Prucalshil-1 Disintegrating Strips causes a bowel movement within 2-3 hours. However, it may take about 4-5 days to show full effect and rapid bowel movements.
Prucalshil-1 Disintegrating Strips is not recommended during pregnancy. Use a reliable method of contraception while taking Prucalshil-1 Disintegrating Strips . Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Take Prucalshil-1 Disintegrating Strips as advised by your doctor. It can be taken at any time of the day. It is usually taken once a day orally with or without food.
Prucalshil-1 Disintegrating Strips has been proven to be beneficial in cases of gastroparesis and constipation. Gastroparesis is a disorder that stops or slows the food movement from stomach to small intestine, even though there is no blockage in the intestines or stomach.
You should avoid taking Prucalshil-1 Disintegrating Strips if you are allergic to it, if you have a tear in your intestinal or stomach wall, a bowel blockage or inflammatory conditions of the intestinal wall like ulcerative colitis or Crohn’s disease. Always consult your doctor before starting Prucalshil-1 Disintegrating Strips .

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