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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 23, 2024 | 4:50 PM IST
Propyzole NF Cream is used to treat fungal skin infections. It contains Clobetasol and Clotrimazole, which blocks the production of chemicals that cause skin redness, swelling and itching. Also, it stops the growth of fungi. Thus, it is used to treat athlete's foot (fungal infection between the toes due to sweating) and jock itch (fungal infection in the skin of the genitals, inner thighs and buttocks). It may cause common side effects of such as burning, irritation, itching, redness and thinning of skin at the application site. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Hegde & Hegde Pharmaceutica Llp

Consume Type

TOPICAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Propyzole NF Cream

Propyzole NF Cream belongs to the class of dermatological medication, primarily used to treat fungal skin infections. Fungal infection occurs when a fungus invades and affects the tissue on the skin. Fungi can live in the air, soil, water and plants. Symptoms of a fungal infection include skin rash, irritation, redness and scaling of the skin. 

Propyzole NF Cream consists of two medicines, namely: Clobetasol (corticosteroid) and Clotrimazole (antifungal). Clobetasol is a highly potent corticosteroid with anti-inflammatory, antipruritic (relieves itching) and vasoconstrictive (narrows blood vessels) properties. It blocks the production of chemical mediators of inflammation (such as kinins, histamine, liposomal enzymes, and prostaglandins) that make the skin red, swollen and itchy. On the other hand, Clotrimazole is an antifungal medication that stops the growth of fungi by causing damage and leakage to the fungal cell membrane. It is also used to treat athlete’s foot (fungal infection between the toes due to sweating) and jock itch (fungal infection in the skin of the genitals, inner thighs and buttocks). 

Use this medication on the skin only as advised by the doctor. Common side effects of Propyzole NF Cream are burning, irritation, itching, redness and thinning of skin at the application site. These side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor. 

Avoid contact with your eyes, nose or mouth while using Propyzole NF Cream. Rinse it off with water thoroughly if you get the cream in these areas. Brief your medical history to doctor, if you are allergic to Propyzole NF Cream or any of its components. Therapy with topical corticosteroids like Clobetasol should be administered cautiously in patients with bacterial, fungal, viral and protozoa infections. Let your doctor know if you have any medical history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases. Please consult your doctor if you are a pregnant or breastfeeding woman before using Propyzole NF Cream.

Uses of Propyzole NF Cream

Treatment of Fungal skin infections.

Medicinal Benefits

Propyzole NF Cream treats fungal skin infections and is a combination of two medicines, namely: Clobetasol and Clotrimazole. Clobetasol is a highly potent corticosteroid with anti-inflammatory, antipruritic (relieves itching) and vasoconstrictive (narrows blood vessels) properties. It blocks the production of chemical mediators of inflammation that make the skin red, swollen and itchy. It effectively treats inflammation and itching caused by plaque psoriasis (skin cells build up to form itchy scales and dry patches) and other skin conditions. Clotrimazole is an antifungal medication that treats fungal infections like vaginal yeast infections, oral thrush and ringworm. It stops the growth of fungi by causing damage and leakage to the fungal cell membrane.

Directions for Use

Cream: Apply the cream onto clean, dry, unbroken skin affected by the infection. Apply it once or twice a day or as suggested. Do not use it on the face and avoid contact with eyes, mouth and nose. Do not put a bandage or a dressing on the affected area while using Propyzole NF Cream unless advised by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Propyzole NF Cream

  • Burning 
  • Irritation 
  • Itching 
  • Redness 
  • Thinning of skin 

Drug Warnings

Brief your medical history to doctor, if you are allergic to Propyzole NF Cream or any of its components. Let your doctor know if you have any history of liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases. Propyzole NF Cream is not recommended for diaper rash. Pregnant and breastfeeding women should use Propyzole NF Cream with proper consultation and caution. Do not use Propyzole NF Cream on the face and avoid contact with eyes, nose and throat. Rinse it off with water thoroughly if you get the cream in these areas. Do not put a bandage or a dressing on the affected area while using Propyzole NF Cream unless advised by the doctor. Always wash hands before and after application of Propyzole NF Cream. Do not store Propyzole NF Cream above 25°C.

Drug Interactions

Drug-Drug Interaction: Propyzole NF Cream may interact with other corticosteroids (prednisone), respiratory-related medicines (budesonide, formoterol) and drugs that lower the immune system (cyclosporine).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: Propyzole NF Cream is contraindicated in fungal, viral, protozoa infections, liver, kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases.

Drug-Drug Interactions Checker List

  • PREDNISONE
  • BUDESONIDE
  • FORMOTEROL
  • CYCLOSPORINE

Habit Forming

No

Diet & Lifestyle Advise

  • Always wear loose-fitting clothes to avoid further sweat and the spread of the fungal infection.
  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • Do not walk barefoot at places like gym showers to prevent fungal infections.
  • Do not scratch the affected area of the skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.
  • Avoid or limit the intake of alcohol and caffeine.
  • Do not scratch or pick your skin to avoid getting the affected area infected.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and sleep peacefully.
  • Use mild soap while taking baths and prefer warm baths.

Special Advise

  • Corticosteroids like Clobetasol may affect blood sugar levels. Please monitor your blood glucose levels regularly if you have diabetes and using Propyzole NF Cream. 
  • Clotrimazole in Propyzole NF Cream may cause abnormal liver functions tests in people with liver impairment. Please let your doctor know if you have any history of liver diseases before undergoing liver function tests and using Propyzole NF Cream.

Disease/Condition Glossary

Fungal infection: A fungal infection (also called mycosis) is a skin disease caused by a fungus when it invades the skin tissue. Fungi can live in the air, soil, water, and plants. Symptoms of a fungal infection include skin rash, irritation, redness and scaling of the skin. Athlete's foot: It is a fungal infection between the toes due to sweating. Jock itch: A fungal infection in the skin of the genitals, inner thighs and buttocks.

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Alcohol

Safe if prescribed

No interaction found of Propyzole NF Cream with alcohol.

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Pregnancy

Caution

There is limited data on how the Propyzole NF Cream affects pregnancy. Propyzole NF Cream may be unsafe to use during pregnancy since it affects the baby. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Propyzole NF Cream.

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Breast Feeding

Caution

It is not known if Propyzole NF Cream passes into the breast milk. Please consult your doctor before taking Propyzole NF Cream if you are breastfeeding. If you need to apply the cream or ointment on your breasts, don't do this shortly before giving a feed.

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Driving

Safe if prescribed

There have been no studies to investigate the effect of Propyzole NF Cream on driving performance or the ability to operate machinery.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Propyzole NF Cream.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Propyzole NF Cream.

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Children

Unsafe

Propyzole NF Cream is not recommended for children less than 12 years of age.

Country of origin

India

Manufacturer/Marketer address

Office No. 11A ? 15, 1st Floor, Free Press House, 215, Nariman Point, Mumbai ? 400 021
Other Info - PRO0238

FAQs

Propyzole NF Cream is used to treat fungal skin infections.
Propyzole NF Cream contains Clobetasol and Clotrimazole. Clobetasol is a corticosteroid that provides relief from itching and redness of infection. Clotrimazole is an antifungal drug that treats various fungal skin infections by killing and preventing fungi growth.
Propyzole NF Cream is for topical (for skin use) application only. Do not use Propyzole NF Cream on the face and avoid contact with eyes. Do not put a bandage or a dressing on the affected area while using Propyzole NF Cream unless advised by the doctor.
Propyzole NF Cream consists of Clobetasol, a corticosteroid that affects the blood sugar levels. It is advised to consult your doctor before using Propyzole NF Cream and monitor your blood sugar levels regularly.
Propyzole NF Cream should be used with proper caution and doctor consultation if you have any bacterial, fungal, viral and protozoa infections, liver or kidney diseases, glaucoma, cataract, poor blood circulation, immune system problems, diabetes and adrenal gland diseases.
Do not stop using Propyzole NF Cream even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.
Clotrimazole in Propyzole NF Cream may cause abnormal liver functions tests in people with liver impairment. Please let your doctor know if you have any history of liver diseases before undergoing any liver function tests.
Clean and dry the affected area and apply Propyzole NF Cream as a thin layer as advised by the doctor.
Propyzole NF Cream should be used for as long as it has been prescribed by the doctor. The doctor will determine the duration of the treatment based on your condition.
Common side effects of Propyzole NF Cream include burning, irritation, itching, redness and thinning of skin at the application site. These side effects do not require medical attention and gradually resolve over time. If these side effects persist longer, please consult your doctor.

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