Premoquin 64.5mg Injection belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Extraintestinal amebiasis is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver.

Premoquin 64.5mg Injection contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Thereby treats malaria ans extraintestinal amebiasis.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Premoquin 64.5mg Injection include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood/confusion, vision changes/blurred vision, black or tarry stools, bleeding gums, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you are allergic to any of the components in Premoquin 64.5mg Injection. Inform your doctor if you have any liver or kidney problems, fits, heart diseases, hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Premoquin 64.5mg Injection. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Premoquin 64.5mg Injection may cause dizziness; hence do not drive or operate machinery until you are alert. Avoiding alcohol during the treatment is recommended to rule out any possibility of worsening side effects. Premoquin 64.5mg Injection should be used for children only when prescribed by a doctor.

Premoquin 64.5mg Injection contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is effective against parasitic species, including Plasmodium vivax, Plasmodium malariae, and susceptible strains of Plasmodium falciparum. Premoquin 64.5mg Injection is useful in extending the interval between treatment and relapse in patients with malaria or vivax malaria. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Chloroquine also has off-label uses in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus.

• Nausea 
• Vomiting 
• Diarrhoea 
• Stomach cramps 
• Headache 
• Hair loss 
• Changes in mood/confusion 
• Vision changes/blurred vision 
• Black or tarry stools 
• Bleeding gums 
• Dizziness 

Before using Premoquin 64.5mg Injection, inform your doctor if you have recently used any prescription and non-prescription medications, including other anti-malarial drugs. Inform your doctor if you have any allergic reactions, liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency, electrolyte imbalance, psoriasis, alcoholism, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems. Please seek medical advice if you are pregnant or breastfeeding before taking Premoquin 64.5mg Injection. This medicine may cause dizziness; hence drive or operate machinery only when you are alert. Do not consume alcohol while being treated with Premoquin 64.5mg Injection.

Drug-Drug Interaction: Premoquin 64.5mg Injection may interact with heartburn medicines (cimetidine), antibiotics (ampicillin), immunosuppressants (cyclosporin), antacids, and kaolin (clay mineral used as filler in tablets).

Drug-Food Interaction: Avoid alcohol consumption while using Premoquin 64.5mg Injection.

Drug-Disease Interaction: Before using Premoquin 64.5mg Injection, let your doctor know if you have any heart diseases, liver or kidney problems, diabetes, G-6-PD deficiency, electrolyte imbalance, psoriasis, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems.

• CIMETIDINE
• AMPICILLIN
• CYCLOSPORIN
• KAOLIN

Malaria:

• Take nutritious food, including fresh fruits and vegetables, to help recover from malarial fever.

• During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.

• Include high-fibre foods like green leafy vegetables and fruits to aid digestion.

• Take proper rest to help your body relax and heal faster.

• Avoid or limit the intake of alcohol and caffeine.

Extra intestinal Amebiasis:

• Include fruits, vegetables, whole-grain bread, low-fat dairy products, beans, lean meats, and fish in your diet.

• Avoid alcohol consumption that can further damage your liver in liver abscess.

• Wash your hands often to prevent infection.

• Stay away from patients who are infected with amebiasis.

Let your doctor/laboratory staff know that you are taking Premoquin 64.5mg Injection if you are undergoing any medical tests.

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This is a common disease in Africa, South America, and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria, and P. falciparum. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Extraintestinal Amebiasis: It is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver. When the parasite infects the liver, it leads to an amoebic liver abscess (collection of pus in the liver). An amoebic liver abscess can further cause fever and right upper quadrant abdominal pain. Apart from the liver, other body areas that can be affected by extraintestinal amebiasis include pleuropulmonary (pleura and the lungs), cardiac (heart), cerebral (brain), renal (kidneys), genitourinary (genital and urinary tracts), and cutaneous (related to skin) sites.