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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Lariago Injection 5 ml is an anti-malarial medication used in the treatment of malaria and extraintestinal Amebiasis. This medicine contains chloroquine which causes the death of the parasite by increasing the concentration of a toxic compound in the parasite. Common side effects include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood, etc.
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Prescription drug

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Synonym

CHLOROQUINE PHOSPHATE

Manufacturer/Marketer

Ipca Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Lariago Injection 5 ml

Lariago Injection 5 ml belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Extraintestinal amebiasis is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver.

Lariago Injection 5 ml contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Thereby treats malaria ans extraintestinal amebiasis.

Your doctor will decide the dose and duration based on your medical condition. Common side effects of Lariago Injection 5 ml include nausea, vomiting, diarrhoea, stomach cramps, headache, hair loss, changes in mood/confusion, vision changes/blurred vision, black or tarry stools, bleeding gums, and dizziness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you are allergic to any of the components in Lariago Injection 5 ml. Inform your doctor if you have any liver or kidney problems, fits, heart diseases, hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Lariago Injection 5 ml. It is essential to let your doctor know if you are pregnant, planning to conceive, or are a breastfeeding mother. Lariago Injection 5 ml may cause dizziness; hence do not drive or operate machinery until you are alert. Avoiding alcohol during the treatment is recommended to rule out any possibility of worsening side effects. Lariago Injection 5 ml should be used for children only when prescribed by a doctor.

Uses of Lariago Injection 5 ml

Treatment of Malaria and Extraintestinal Amebiasis

Medicinal Benefits

Lariago Injection 5 ml contains Chloroquine. It works by increasing the concentration of a toxic compound in the parasite that leads to its death. It is effective against parasitic species, including Plasmodium vivax, Plasmodium malariae, and susceptible strains of Plasmodium falciparum. Lariago Injection 5 ml is useful in extending the interval between treatment and relapse in patients with malaria or vivax malaria. It is also amoebicidal in action and destroys the parasitic amoebas causing amoebiasis. Chloroquine also has off-label uses in treating autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus.

Directions for Use

Lariago Injection 5 ml will be injected by a healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lariago Injection 5 ml

  • Nausea 
  • Vomiting 
  • Diarrhoea 
  • Stomach cramps 
  • Headache 
  • Hair loss 
  • Changes in mood/confusion 
  • Vision changes/blurred vision 
  • Black or tarry stools 
  • Bleeding gums 
  • Dizziness 

Drug Warnings

Before using Lariago Injection 5 ml, inform your doctor if you have recently used any prescription and non-prescription medications, including other anti-malarial drugs. Inform your doctor if you have any allergic reactions, liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency, electrolyte imbalance, psoriasis, alcoholism, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems. Please seek medical advice if you are pregnant or breastfeeding before taking Lariago Injection 5 ml. This medicine may cause dizziness; hence drive or operate machinery only when you are alert. Do not consume alcohol while being treated with Lariago Injection 5 ml.

Drug Interactions

Drug-Drug Interaction: Lariago Injection 5 ml may interact with heartburn medicines (cimetidine), antibiotics (ampicillin), immunosuppressants (cyclosporin), antacids, and kaolin (clay mineral used as filler in tablets).

Drug-Food Interaction: Avoid alcohol consumption while using Lariago Injection 5 ml.

Drug-Disease Interaction: Before using Lariago Injection 5 ml, let your doctor know if you have any heart diseases, liver or kidney problems, diabetes, G-6-PD deficiency, electrolyte imbalance, psoriasis, porphyria, hearing problems, vision-related issues, fits, and damaged retina or vision problems.

Drug-Drug Interactions Checker List

  • CIMETIDINE
  • AMPICILLIN
  • CYCLOSPORIN
  • KAOLIN

Habit Forming

No

Diet & Lifestyle Advise

Malaria:

  • Take nutritious food, including fresh fruits and vegetables, to help recover from malarial fever.

  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.

  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.

  • Take proper rest to help your body relax and heal faster.

  • Avoid or limit the intake of alcohol and caffeine.

Extra intestinal Amebiasis:

  • Include fruits, vegetables, whole-grain bread, low-fat dairy products, beans, lean meats, and fish in your diet.

  • Avoid alcohol consumption that can further damage your liver in liver abscess.

  • Wash your hands often to prevent infection.

  • Stay away from patients who are infected with amebiasis.

Special Advise

Let your doctor/laboratory staff know that you are taking Lariago Injection 5 ml if you are undergoing any medical tests.

Disease/Condition Glossary

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This is a common disease in Africa, South America, and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria, and P. falciparum. Malaria symptoms usually start ten days to 4 weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Extraintestinal Amebiasis: It is a parasitic infection caused by Entamoeba histolytica that spreads to various organs, most commonly the liver. When the parasite infects the liver, it leads to an amoebic liver abscess (collection of pus in the liver). An amoebic liver abscess can further cause fever and right upper quadrant abdominal pain. Apart from the liver, other body areas that can be affected by extraintestinal amebiasis include pleuropulmonary (pleura and the lungs), cardiac (heart), cerebral (brain), renal (kidneys), genitourinary (genital and urinary tracts), and cutaneous (related to skin) sites.

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Alcohol

Caution

Avoid alcohol while using Lariago Injection 5 ml since it can worsen your side effects.

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Pregnancy

Caution

There is limited information on how Lariago Injection 5 ml affects pregnancy. Please seek medical advice if you are pregnant or planning to conceive. Your doctor will prescribe Lariago Injection 5 ml only if the benefits outweigh the risks.

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Breast Feeding

Caution

Lariago Injection 5 ml may be excreted into the breast milk when used during lactation. Please consult your doctor before starting Lariago Injection 5 ml if you are a breastfeeding mother.

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Driving

Caution

Lariago Injection 5 ml may make you feel dizzy or cause blurry vision. In such cases, do not drive or operate machinery until you are alert and have a clear vision.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Lariago Injection 5 ml.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Lariago Injection 5 ml.

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Children

Caution

Lariago Injection 5 ml should be used for children only when prescribed by a doctor. Your doctor will decide the dose based on your child's age and body weight.

Country of origin

India

Manufacturer/Marketer address

142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra
Other Info - LAR0002

Author Details

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FAQs

Lariago Injection 5 ml belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. It may also be used to treat extraintestinal amebiasis/amoebiasis. Lariago Injection 5 ml treats malaria by increasing the concentration of a toxic compound in the parasite that leads to its death.
Lariago Injection 5 ml may cause irreversible retinal damage with long-term therapy. Retinopathy (disease related to the retina) is also reported with Chloroquine usage. You may not be advised Lariago Injection 5 ml by your doctor if you have vision changes or retina damage. If the doctor has prescribed you this medicine knowing your medical history, you may be further advised to take ophthalmological examinations, including visual acuity, expert slit-lamp, funduscopic, and visual field tests. If there are any changes in these examinations, you may be asked to discontinue the treatment.
Inform your doctor in advance if you have any liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), electrolyte imbalance, psoriasis, alcoholism, porphyria (a blood disorder), hearing problems, vision-related issues, fits, and damaged retina or vision problems before starting Lariago Injection 5 ml. Also, let your doctor know if you have recently undergone treatment with other anti-malarial drugs.
It is advised not to use Lariago Injection 5 ml for the long term since it may produce retinal toxicity leading to blindness.

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