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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Nov 10, 2024 | 7:18 PM IST
Pregakey NT 75 Tablet 10's is used for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. It contains Pregabalin and Nortriptyline, which affects the chemicals in the brain that send pain signals across the nervous system. Also, it increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. In some cases, you may experience certain common side effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Mk Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Pregakey NT 75 Tablet 10's

Pregakey NT 75 Tablet 10's is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.

Pregakey NT 75 Tablet 10's is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Pregakey NT 75 Tablet 10's helps to treat neuropathic pain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Pregakey NT 75 Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Pregakey NT 75 Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregakey NT 75 Tablet 10's as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Pregakey NT 75 Tablet 10's

Treatment of Neuropathic pain.

Medicinal Benefits

Pregakey NT 75 Tablet 10's is a combination of two medicines, namely: Pregabalin and Nortriptyline. Pregakey NT 75 Tablet 10's is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, Pregakey NT 75 Tablet 10's helps to treat neuropathic pain (pain due to nerve damage).

Side Effects of Pregakey NT 75 Tablet 10's

  • Dizziness
  • Sleepiness
  • Nausea
  • Blurred vision
  • Peripheral oedema (swelling of lower legs and hands)
  • Weight gain
  • Dry mouth

Directions for Use

Take Pregakey NT 75 Tablet 10's with or without food. Swallow Pregakey NT 75 Tablet 10's as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Pregakey NT 75 Tablet 10's if you are allergic to any of its contents. Inform your doctor before taking Pregakey NT 75 Tablet 10's if you have or had heart problems, bipolar syndrome, severe liver disease or if you have taken MAO inhibitors in the last 14 days. Consult your doctor before taking cough-cold medicines containing adrenaline-like drugs such as ephedrine, phenylpropanolamine, isoprenaline, noradrenaline or phenylephrine. Consult your doctor if you are pregnant or breastfeeding. Pregakey NT 75 Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Pregakey NT 75 Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregakey NT 75 Tablet 10's as it could lead to increased drowsiness and sleepiness.

Therapeutic Class

MISCELLANEOUS

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

What if I have taken an overdose of Pregakey NT 75 Tablet 10's

Do not take more than the prescribed dose of Pregakey NT 75 Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pregakey NT 75 Tablet 10's as it may cause increased drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Pregakey NT 75 Tablet 10's; your doctor will decide whether Pregakey NT 75 Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Pregakey NT 75 Tablet 10's may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Pregakey NT 75 Tablet 10's should not be given to children as safety and efficacy have not been established.

Country of origin

India

Manufacturer/Marketer address

Door No. 84, 1st Floor, Gandhi Road, Kottakuppam, ECR, Villupuram, Tamil Nadu 605104
Other Info - PRE2224

Author Details

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FAQs

Pregakey NT 75 Tablet 10's is used to treat neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc.
Pregakey NT 75 Tablet 10's affects the chemicals in the brain that send pain signals across the nervous system. It increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain.
Dry mouth could be a side-effect of Pregakey NT 75 Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
To treat your condition effectually, continue taking Pregakey NT 75 Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregakey NT 75 Tablet 10's.
Pregakey NT 75 Tablet 10's is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.
Pregakey NT 75 Tablet 10's may cause peripheral oedema. Peripheral oedema is the swelling of hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
Pregakey NT 75 Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Pregakey NT 75 Tablet 10's is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, they help treat neuropathic pain.
When taking Pregakey NT 75 Tablet 10's, you must be mindful of your diet and lifestyle to maintain a healthy weight. This medication combination can increase your appetite, leading to weight gain. Focus on nutrient-dense foods, be mindful of your portion sizes, and avoid high-calorie snacks like crisps, cakes, biscuits, and sweets. Instead, opt for fresh fruits and vegetables, low-calorie foods, whole grains, and lean protein sources. Regular exercise will also help stabilize your weight and support overall health and well-being.
Pregakey NT 75 Tablet 10's causes sleepiness or drowsiness as a common side effect. Because Pregakey NT 75 Tablet 10's is a tricyclic antidepressant that increases the levels of certain neurotransmitters (serotonin and noradrenaline) in the brain and works by modulating calcium channel activity in nerve cells, which can lead to drowsiness as a side effect, this side effect does not require medical attention and will resolve gradually over time. It's essential to be cautious when engaging in activities that require alertness, such as driving or operating heavy machinery. However, you are advised to talk to your doctor if you experience these side effects persistently.
Taking Pregakey NT 75 Tablet 10's can affect your sexual life. You might experience lower sex drive, erectile dysfunction, or problems with ejaculation or orgasm. If you notice any of these changes, it's important to tell your doctor. They can help you find solutions or adjust your medication to minimize these effects. Remember, being open and honest about your sexual health is crucial in managing potential side effects and finding the best treatment for you.
Most common side effects of Pregakey NT 75 Tablet 10's tend to subside as your body adapts to the medication. However, in rare cases, you may experience severe reactions, including allergic responses, significant mood changes (such as suicidal ideation), seizures, or irregular heartbeats. If you encounter any of these symptoms, seek medical attention immediately. Prompt treatment can help address these issues and ensure your safety. Remember, it's always best to consult with your healthcare provider if you have concerns.
The time it takes for Pregakey NT 75 Tablet 10's to take effect can vary considerably from person to person. While some people may start feeling better after a couple of weeks, it may take up to 4-6 weeks to experience the full benefits. The exact duration of treatment will depend on your individual medical condition, and your doctor will provide personalized guidance on the recommended course of treatment.
If you forget to take Pregakey NT 75 Tablet 10's, take it as soon as you remember. A small variation in time may not show much effect. If it is too late, continue taking the next dose as indicated, But never take a double dose in your next dose. Consult your doctor if you are uncomfortable or experiencing symptoms.
Never use a greater quantity of medicine than prescribed. Pregakey NT 75 Tablet 10's may cause serious side effects such as abnormal heartbeat, seizures, allergic reactions, and suicidal ideation. Please inform your doctor and get medical assistance as soon as possible to avoid major complications.
Taking more than the recommended dosage does not provide additional relief and can increase the risk of adverse effects and long-term health complications.
While taking Pregakey NT 75 Tablet 10's, it's crucial to be mindful of potential interactions and risks. Avoid excessive alcohol consumption, as it may intensify side effects, and refrain from driving or operating heavy machinery until you understand how the medication affects you. Additionally, consult your doctor before taking other medications or supplements to prevent interactions, and limit grapefruit or grapefruit juice intake, as it may impact absorption. Sudden changes in diet or exercise routines should also be avoided. Furthermore, exercise caution when taking medications containing opioids, as they may interact with Pregakey NT 75 Tablet 10's. By following your doctor's guidance and being aware of these potential interactions, you can minimize risks and ensure the medication works effectively for you.
Regular check-ins with your doctor are crucial when receiving medical treatment to monitor your progress and address any concerns. The frequency of visits may vary depending on your individual situation, but typically, you can expect to see your doctor regularly during the initial treatment phase to adjust treatment plans and monitor side effects. During maintenance, periodic check-ins will also help track your progress and address any concerns.
Storage: Store the Pregakey NT 75 Tablet 10's in its original container to protect it from the external environment. Keep the medication out of reach of children. Store in a cool and dry place away from sunlight.Disposal: Do not consume it after the expiration date.Check the expiration date, remove the label, keep it in a plastic bag, and throw it in household trash. Do not flush the medication down the toilet or sink.
No, Pregakey NT 75 Tablet 10's is not an OTC drug; it cannot be given directly without a registered medical practitioner prescription.
The most common side effects of the Pregakey NT 75 Tablet 10's are blurred vision, dizziness, dry mouth, peripheral oedema (swelling of lower legs and hands), nausea, sleepiness, and weight gain. These side effects may not cause many complications but gradually decrease over time. If you feel any discomfort, contact your doctor; you may get guidance to suppress your discomfort.
Pregakey NT 75 Tablet 10's may interact with antidepressants (amitriptyline, duloxetine, mirtazapine, fluoxetine, sertraline, citalopram, escitalopram, bupropion), pain killer (codeine, fentanyl, hydrocodone, morphine, oxycodone, tramadol, acetaminophen), anti-convulsant (gabapentin, phenobarbital, phenytoin, clonazepam, topiramate), anti-anxiety (diazepam, alprazolam), sedative-hypnotics (zolpidem), antihistamine (diphenhydramine, cetirizine), muscle relaxant (cyclobenzaprine), antiemetic (ondansetron). So, please confirm with your doctor about pre-existing diseases and your present medication. Your doctor will weigh the risks and suggest the medication to avoid drug interactions.
While using Pregakey NT 75 Tablet 10's, following a healthy diet and lifestyle is essential to maximize the medication's effectiveness and minimize potential side effects. Eat a balanced diet rich in whole foods, fruits, vegetables, and whole grains, and stay hydrated by drinking plenty of water. Limit your intake of processed and high-sugar foods, and exercise regularly with activities like walking or light physical activity to maintain overall health. Aim for 7-8 hours of sleep per night to help your body recover and manage stress through relaxation techniques like meditation or deep breathing. Additionally, avoid excessive alcohol consumption and smoking. Following these guidelines and consulting your doctor for personalized advice can optimize your treatment and improve your overall well-being.
The most crucial advice while using any medication is to prioritize your mental health and safety. If you're using a medication that can increase the risk of suicidal thoughts or behaviour, it's essential to be closely monitored by your healthcare provider. If you experience any thoughts or feelings of self-harm, it's vital to seek help immediately. Don't hesitate to reach out to your doctor or a crisis helpline for support. Remember, your well-being is the top priority; timely intervention can make a significant difference.
Pregakey NT 75 Tablet 10's can be taken with or without food. Swallow it as a whole with a glass of water, do not chew or break it. Always follow your physician's instructions for how much and how many doses to take. Also, inform your doctor if you are having any discomfort; they will guide you in managing it.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
There have been no long-term side effects reported as of now. If you experience any side effects that persist, please stop taking the medication and consult the doctor immediately.
Pregakey NT 75 Tablet 10's is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant).
Pregakey NT 75 Tablet 10's should not be given to children as safety and efficacy have not been established. Please reach out to the doctor for more assistance.

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