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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:45 PM IST
Posanat 300 mg Injection 16.7 ml is used to prevent and treat fungal infections. It contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.
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Prescription drug

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Composition :

POSACONAZOLE-18MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Posanat 300 mg Injection 16.7 ml

Posanat 300 mg Injection 16.7 ml is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. Besides this, it is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Any disease caused by a fungus is known as a fungal infection.

Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Posanat 300 mg Injection 16.7 ml will be administered by a qualified healthcare professional. You may sometimes experience injection site reactions, fever, headache, chills or shaking, stomach pain, constipation, diarrhoea, nosebleeds and coughing. Most of these side effects of Posanat 300 mg Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posanat 300 mg Injection 16.7 ml or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posanat 300 mg Injection 16.7 ml only if the benefits outweigh the risk. Before taking the Posanat 300 mg Injection 16.7 ml, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posanat 300 mg Injection 16.7 ml

Treatment of Fungal infections

Medicinal Benefits

It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. It is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Side Effects of Posanat 300 mg Injection 16.7 ml

  • Injection site reactions
  • Fever
  • Headache
  • Chills or shaking
  • Constipation
  • Stomach pain
  • Diarrhoea
  • Nosebleeds
  • Coughing

Directions for Use

Posanat 300 mg Injection 16.7 ml will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Keep your doctor informed about your health condition and medicines to rule out any side effects. Posanat 300 mg Injection 16.7 ml is restricted to people sensitive to product constituents or other antifungal medicines. During pregnancy and lactation, posaconazole should only be used after careful risk/benefit considerations, so before taking Posanat 300 mg Injection 16.7 ml, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is unknown whether it is safe to consume alcohol with Posanat 300 mg Injection 16.7 ml. However, as a precautionary measure, it is advisable not to take or limit alcohol.

Therapeutic Class

ANTIFUNGALS

Drug-Drug Interactions

verifiedApollotooltip
PosaconazoleRanolazine
Critical
PosaconazolePimozide
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Posanat 300 mg Injection 16.7 ml for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posanat 300 mg Injection 16.7 ml.
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcoholic beverages and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during the Posanat 300 mg Injection 16.7 ml treatment to enhance a healthy lifestyle practice.

Habit Forming

No

How Posanat 300 mg Injection 16.7 ml Works

Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

What if I have taken an overdose of Posanat 300 mg Injection 16.7 ml

Since Posanat 300 mg Injection 16.7 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Caution

Limit or avoid consumption of alcohol while on treatment with Posanat 300 mg Injection 16.7 ml as it may increase the risk of serious side effects.

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Pregnancy

Caution

Posanat 300 mg Injection 16.7 ml is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posanat 300 mg Injection 16.7 ml.

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Breast Feeding

Caution

There is no substantial research yet on using Posanat 300 mg Injection 16.7 ml in breastfeeding women. Inform your doctor if you are a nursing mother before taking Posanat 300 mg Injection 16.7 ml; your doctor will decide whether Posanat 300 mg Injection 16.7 ml can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Posanat 300 mg Injection 16.7 ml alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Inform your doctor before receiving the Posanat 300 mg Injection 16.7 ml if you have a liver impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor before receiving the Posanat 300 mg Injection 16.7 ml if you have a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe a suitable dose based on your child's age and condition.

Country of origin

INDIA

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Other Info - POS0079

Author Details

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FAQs

Posanat 300 mg Injection 16.7 ml is used to treat Fungal infections.
Posanat 300 mg Injection 16.7 ml contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Posanat 300 mg Injection 16.7 ml is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posanat 300 mg Injection 16.7 ml.
If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.
Posanat 300 mg Injection 16.7 ml may cause side effects like injection site reactions, diarrhoea, nausea, fever, vomiting, headache and coughing, although not everybody gets them. Most of these side effects of Posanat 300 mg Injection 16.7 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
In some cases, using Posanat 300 mg Injection 16.7 ml may lead to nosebleeds as a side effect. It does not require medical attention and gradually resolves over time. However, if the side effects persist or worsen, please consult your doctor.
Posanat 300 mg Injection 16.7 ml will be administered by a qualified healthcare professional. Please do not self-administer.
Yes, Posanat 300 mg Injection 16.7 ml is effective in the treatment of fungal infections and prevention of invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs).

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