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Written By , M Pharmacy
Reviewed By , MPharma., PhD
Last Updated Jan 1, 2025 | 2:45 PM IST
Posalup 300Mg/16.7Ml Injection is used to prevent and treat fungal infections. It contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.
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Prescription drug

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Composition :

POSACONAZOLE-18MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Posalup 300Mg/16.7Ml Injection

Posalup 300Mg/16.7Ml Injection is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. Besides this, it is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Any disease caused by a fungus is known as a fungal infection.

Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Posalup 300Mg/16.7Ml Injection will be administered by a qualified healthcare professional. You may sometimes experience injection site reactions, fever, headache, chills or shaking, stomach pain, constipation, diarrhoea, nosebleeds and coughing. Most of these side effects of Posalup 300Mg/16.7Ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posalup 300Mg/16.7Ml Injection or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posalup 300Mg/16.7Ml Injection only if the benefits outweigh the risk. Before taking the Posalup 300Mg/16.7Ml Injection, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posalup 300Mg/16.7Ml Injection

Treatment of Fungal infections

Medicinal Benefits

It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. It is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Side Effects of Posalup 300Mg/16.7Ml Injection

  • Injection site reactions
  • Fever
  • Headache
  • Chills or shaking
  • Constipation
  • Stomach pain
  • Diarrhoea
  • Nosebleeds
  • Coughing

Directions for Use

Posalup 300Mg/16.7Ml Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Keep your doctor informed about your health condition and medicines to rule out any side effects. Posalup 300Mg/16.7Ml Injection is restricted to people sensitive to product constituents or other antifungal medicines. During pregnancy and lactation, posaconazole should only be used after careful risk/benefit considerations, so before taking Posalup 300Mg/16.7Ml Injection, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is unknown whether it is safe to consume alcohol with Posalup 300Mg/16.7Ml Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.

Therapeutic Class

ANTIFUNGALS

Drug-Drug Interactions

verifiedApollotooltip
PosaconazoleSaquinavir
Critical
PosaconazoleIvabradine
Critical

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Posalup 300Mg/16.7Ml Injection for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posalup 300Mg/16.7Ml Injection.
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcoholic beverages and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during the Posalup 300Mg/16.7Ml Injection treatment to enhance a healthy lifestyle practice.

Habit Forming

No

How Posalup 300Mg/16.7Ml Injection Works

Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

What if I have taken an overdose of Posalup 300Mg/16.7Ml Injection

Since Posalup 300Mg/16.7Ml Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.
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Alcohol

Caution

Limit or avoid consumption of alcohol while on treatment with Posalup 300Mg/16.7Ml Injection as it may increase the risk of serious side effects.

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Pregnancy

Caution

Posalup 300Mg/16.7Ml Injection is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posalup 300Mg/16.7Ml Injection.

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Breast Feeding

Caution

There is no substantial research yet on using Posalup 300Mg/16.7Ml Injection in breastfeeding women. Inform your doctor if you are a nursing mother before taking Posalup 300Mg/16.7Ml Injection; your doctor will decide whether Posalup 300Mg/16.7Ml Injection can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Posalup 300Mg/16.7Ml Injection alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Inform your doctor before receiving the Posalup 300Mg/16.7Ml Injection if you have a liver impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor before receiving the Posalup 300Mg/16.7Ml Injection if you have a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe a suitable dose based on your child's age and condition.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - POS0122

Author Details

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FAQs

Posalup 300Mg/16.7Ml Injection is used to treat Fungal infections.
Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in inhibiting fungal cell growth and, ultimately, cell death. Thus, it treats infections.
Posalup 300Mg/16.7Ml Injection is not recommended for coadministration with anticoagulants, So if you are under anticoagulant therapy, inform your doctor before prescribing Posalup 300Mg/16.7Ml Injection.
If you are allergic to posaconazole or similar antifungals such as fluconazole, itraconazole, ketoconazole, or voriconazole, you should not use it. When combined with certain medications, posaconazole can have unfavourable or dangerous side effects.
Posalup 300Mg/16.7Ml Injection may cause side effects like injection site reactions, diarrhoea, nausea, fever, vomiting, headache and coughing, although not everybody gets them. Most of these side effects of Posalup 300Mg/16.7Ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
In some cases, using Posalup 300Mg/16.7Ml Injection may lead to nosebleeds as a side effect. It does not require medical attention and gradually resolves over time. However, if the side effects persist or worsen, please consult your doctor.
Posalup 300Mg/16.7Ml Injection will be administered by a qualified healthcare professional. Please do not self-administer.
Yes, Posalup 300Mg/16.7Ml Injection is effective in the treatment of fungal infections and prevention of invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs).

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