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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:31 PM IST
Palbinas 125 Capsule 21's is an anti-cancer medicine used in the treatment of certain types of breast cancer. This medicine contains palbociclid which works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Common side effects include weakness, loss of appetite, infections and dry skin.
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Composition :

PALBOCICLIB-125MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Palbinas 125 Capsule 21's

Palbinas 125 Capsule 21's belongs to the group of anti-cancer drugs used to treat certain types of breast cancer. Cancer is the uninhibited and uncontrolled growth of cells in the body. Breast cancer is cancer that forms in the cells of the breast. It can form in the lobules, ducts or tubules of the breast or in the breast tissue itself.

Palbinas 125 Capsule 21's contains Palbociclib that works by blocking proteins necessary for cell growth, thereby causing cell death and arresting the uncontrolled production of new cells. Thus, Palbinas 125 Capsule 21's is effective in controlling cancer cells from multiplying and is used in the treatment of breast cancer. 

Take Palbinas 125 Capsule 21's as prescribed. In some cases, Palbinas 125 Capsule 21's may cause certain common side effects such as weakness, loss of appetite, infections and dry skin. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbinas 125 Capsule 21's if you are pregnant or breastfeeding. Palbinas 125 Capsule 21's may cause tiredness, so drive only if you are alert. Palbinas 125 Capsule 21's is not recommended for use in children below 18years. Keep your doctor informed about your health condition and medications to rule out any interactions.

Uses of Palbinas 125 Capsule 21's

Treatment of Breast Cancer

Medicinal Benefits

Palbinas 125 Capsule 21's is an anti-cancer drug used in the treatment of a particular type of breast cancer that is hormone receptor-positive and human epidermal growth factor receptor-2-negative. Palbinas 125 Capsule 21's works by blocking the production of proteins called cyclin-dependent kinase 4 and 6 that are responsible for cell growth and division. By blocking them, Palbinas 125 Capsule 21's nips cell growth in the bud and prevents cancer cells from spreading further. Thus, Palbinas 125 Capsule 21's helps treat breast cancer.

Side Effects of Palbinas 125 Capsule 21's

  • Loss of appetite
  • Dry skin
  • Weakness
  • Infection
  • Hair loss
  • Fever
  • Inflammation of the mouth and lips

Directions for Use

Take Palbinas 125 Capsule 21's preferably with a meal. Swallow it as a whole with water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take St. John's wort or grapefruit/grapefruit juice with Palbinas 125 Capsule 21's. It is advisable to inform the doctor if you are allergic to any of its components. Do not take Palbinas 125 Capsule 21's if you are pregnant or breastfeeding. Palbinas 125 Capsule 21's may cause tiredness, so drive only if you are alert. Palbinas 125 Capsule 21's is not recommended for use in children below 18years. If you experience any signs or symptoms of infections, inform your doctor. Keep your doctor informed about your health condition and medications to rule out any interactions. Consult your doctor immediately if you experience symptoms such as dry cough, chest pain, difficulty breathing or shortness of breath as it could be an indication of lung inflammation

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

verifiedApollotooltip
PalbociclibPosaconazole
Severe
PalbociclibMorphine
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in cancers.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

What if I have taken an overdose of Palbinas 125 Capsule 21's

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, and neutropenia (low neutrophil levels). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Caution

It is not recommended to use alcohol with Palbinas 125 Capsule 21's. Please consult your doctor if you have any concerns.

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Pregnancy

Unsafe

Palbinas 125 Capsule 21's is not recommended for use in pregnancy. Please consult your doctor if you have any concerns.

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Breast Feeding

Unsafe

Palbinas 125 Capsule 21's is not recommended during breastfeeding. Please consult your doctor in case of any concerns.

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Driving

Caution

Palbinas 125 Capsule 21's may cause tiredness and lethargy, which may affect your ability to drive. Do not drive if you experience any side effects after using Palbinas 125 Capsule 21's.

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Liver

Caution

Exercise caution before using Palbinas 125 Capsule 21's in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Palbinas 125 Capsule 21's in case of established kidney disease. Please consult your doctor to address any concerns.

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Children

Unsafe

Palbinas 125 Capsule 21's is not recommended for use in children under 18 years of age. Please consult your doctor in case of any concerns.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai 400 026.
Other Info - PAL0255

Author Details

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FAQs

Palbinas 125 Capsule 21's belongs to the group of anti-cancer drugs used to treat certain types of breast cancer.
Palbinas 125 Capsule 21's works blocking proteins responsible for cell growth and division, thereby arresting the progression of cancer cells.
Do not stop taking Palbinas 125 Capsule 21's on your own. You are advised to take Palbinas 125 Capsule 21's for as long as your doctor has prescribed it for you depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Palbinas 125 Capsule 21's.
A fibroadenoma is a benign state. Palbinas 125 Capsule 21's is indicated only in case of cancers. Please consult your doctor in case of any concerns.
Palbinas 125 Capsule 21's can reduce fertility in men. Therefore, consider sperm preservation before starting Palbinas 125 Capsule 21's if you wish to father a child in the future. Effects on female fertility have not been established. Please consult your doctor before using Palbinas 125 Capsule 21's.
Palbinas 125 Capsule 21's may reduce white blood cell count, thereby weakening the immune system. This might increase your risk of infections. If you notice any signs or symptoms of infections, consult your doctor.
Palbinas 125 Capsule 21's is a type of targeted cancer drug. It is a treatment for breast cancer that is oestrogen receptor-positive (ER+) and human epidermal growth factor receptor-negative (HER2 -).
The duration of taking Palbinas 125 Capsule 21's varies from person to person. You take it in cycles (21 days on, 7 days off.), and as long as it's working and manageable, you continue the treatment. Your healthcare team will monitor your progress and adjust the treatment plan as needed.
Most side effects associated with Palbinas 125 Capsule 21's are temporary and can be effectively managed. However, certain side effects may persist or have a lasting impact in some cases. Common reversible side effects include fatigue, nausea, and hair loss, which typically resolve once treatment is stopped. In rare instances, more serious and potentially irreversible side effects may occur, such as permanent hair loss, increased infection risk, or heart problems. Regular monitoring and open communication with your healthcare team are essential to mitigate these risks and address any concerns that may arise during treatment.
Yes, Palbinas 125 Capsule 21's treatment requires blood count monitoring. If neutropenia is mild in the first six cycles, monitor blood counts every 3 months afterwards. This monitoring schedule helps healthcare providers track potential changes in blood counts and adjust treatment accordingly.
Take Palbinas 125 Capsule 21's exactly as your healthcare provider tells you. Swallow the capsule whole with water on an empty stomach at the same time each day. Follow the treatment schedule.
While using Palbinas 125 Capsule 21's, birth control is necessary to prevent pregnancy. Female patients must take a pregnancy test before starting treatment and use birth control during treatment and for at least 3 weeks after the final dose. Male patients, along with their partners, should also use birth control during treatment and for 3 months after the final dose. It's crucial to inform your doctor if you're pregnant, plan to become pregnant, or plan to father a child so they can guide you on the appropriate measures to take.
While women's fertility may not be affected, Palbinas 125 Capsule 21's can decrease fertility in men. Men taking palbociclib may want to talk to their treatment team about sperm preservation before starting treatment.
In some cases, side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment: fever, chills, or signs of infection; difficulty breathing or shortness of breath; cough with or without mucus; chest pain; dizziness; fast, irregular, or pounding heartbeat; weakness; unusual bleeding or bruising; nosebleeds; or redness, pain, swelling, or blisters on the palms of your hands or soles of your feet, as well as skin blistering, peeling, or redness.

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