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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 13, 2024 | 11:24 AM IST

Osteofrac Cartridge 3 ml is primarily used to treat hypocalcemia caused by hypoparathyroidism. It contains the Parathyroid hormone, which works by allowing the body to absorb more calcium into the blood. Common side effects of this medication are tingling, tickling, or burning feeling of the skin, a sense of numbness, pain in the arms, legs, joints, stomach, or neck, headache and diarrhoea.

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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-26

for this medicine

About Osteofrac Cartridge 3 ml

Osteofrac Cartridge 3 ml belongs to the class of medications called hormones. It is primarily used to treat hypocalcemia caused by hypoparathyroidism. Hypocalcemia is a curable condition that occurs when the calcium levels in your blood are abnormally low. Hypoparathyroidism is a disorder in which the body fails to produce enough parathyroid hormone [PTH; a natural substance required to regulate calcium levels in the blood].

Osteofrac Cartridge 3 ml contains Parathyroid hormone. It works by allowing the body to absorb more calcium into the blood.

A healthcare professional will administer Osteofrac Cartridge 3 ml. Sometimes, you may experience certain common side effects, including tingling, tickling, or burning feeling of the skin, a sense of numbness, pain in the arms, legs, joints, stomach, or neck, headache and diarrhoea. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, consult a doctor.

Osteofrac Cartridge 3 ml should not be used to treat low calcium levels in the blood in people whose condition can be controlled by calcium and vitamin D alone. So, before taking the Osteofrac Cartridge 3 ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Osteofrac Cartridge 3 ml should not be used in pregnant women or nursing mothers unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy or nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Osteofrac Cartridge 3 ml.

Uses of Osteofrac Cartridge 3 ml

Treatment of Hypocalcemia

Medicinal Benefits

Osteofrac Cartridge 3 ml contains Parathyroid hormone, which belongs to the hormone class of drugs and is mostly used to treat hypocalcemia caused by hypoparathyroidism. It works by allowing the body to absorb more calcium into the blood. Osteofrac Cartridge 3 ml regulates calcium levels in the blood. Precise calcium levels are crucial in the human body since even tiny changes can cause muscle and nerve problems.

Directions for Use

Osteofrac Cartridge 3 ml will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Osteofrac Cartridge 3 ml

  • Nausea
  • Vomiting
  • Constipation
  • Low energy
  • Muscle weakness
  • Tingling, tickling, or burning feeling of the skin
  • Sense of numbness
  • Pain in the arms, legs, joints, stomach, or neck
  • Headache
  • Diarrhea

Drug Warnings

Do not take Osteofrac Cartridge 3 ml if you are allergic to its ingredients. If you are unsure, check with your healthcare professional. Inform your doctor if you are taking medicines other than Osteofrac Cartridge 3 ml. Care and close monitoring should be exercised when using this agent in patients with hypercalcemia, bone diseases such as Paget's disease, bone cancer, or cancer that has spread to the bone and severe renal impairment or on dialysis. So, inform about all your medical conditions, sensitivities, and all medications you are using.

Drug Interactions

Drug-Drug Interactions: Osteofrac Cartridge 3 ml may interact with medicines used to manage and treat heart failure and certain arrhythmias (e.g. digoxin, digitoxin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Osteofrac Cartridge 3 ml may interact with various disease conditions, including hypercalcemia, bone diseases such as Paget's disease, bone cancer, or cancer that has spread to the bone and severe renal impairment or on dialysis.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • DIGITOXIN

Habit Forming

No

Diet & Lifestyle Advise

  • Consume a well-balanced and healthy diet.
  • Keep your weight under control with a BMI of 19.5-24.9
  • Eat low-phosphorus foods such as sourdough bread, corn or rice cereals, cream of wheat, unsalted popcorn and some light-coloured sodas & lemonade.
  • Avoid high-phosphorus foods, including bran cereals, oatmeal, nuts, sunflower seeds, whole-grain bread and dark-coloured colas.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of illness.

Special Advise

  • Monitor your calcium levels regularly during treatment with Osteofrac Cartridge 3 ml. Inform your doctor if you notice signs of low calcium levels, such as numbness or tingling around the mouth or muscle aches.

Disease/Condition Glossary

Hypocalcemia: Hypocalcemia is a curable condition that occurs when the calcium levels in your blood are abnormally low. Hypocalcemia can result from a variety of medical disorders. The most common symptoms of hypocalcemia are paresthesia, muscle spasms, cramps, tetany, circumoral numbness, and convulsions.

Hypoparathyroidism: Hypoparathyroidism is a disorder in which the body fails to produce enough parathyroid hormone [PTH; a natural substance required to regulate calcium levels in the blood].

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Alcohol

Caution

Consuming alcohol along with Osteofrac Cartridge 3 ml is not advisable as it may cause unpleasant side effects.

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Pregnancy

Caution

Osteofrac Cartridge 3 ml should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. So, inform your doctor if you are pregnant or planning to become pregnant. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Before taking this medicine, the risks and benefits should be discussed with the doctor. Your doctor may advise discontinuing the medication or breastfeeding based on your medical condition.

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Driving

Caution

It is not known whether Osteofrac Cartridge 3 ml alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Caution

Limited information was available about using Osteofrac Cartridge 3 ml in patients with liver disease. Inform your doctor before receiving the Osteofrac Cartridge 3 ml if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Care and close monitoring should be exercised when using this agent in patients with severe renal impairment or on dialysis. Inform your doctor before receiving the Osteofrac Cartridge 3 ml if you have a history of kidney diseases/conditions.

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Children

Caution

There was limited information about the usage of Osteofrac Cartridge 3 ml in paediatric patients. Please seek medical advice. Your doctor will only prescribe if the benefits outweigh the risks.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - OST0553

Author Details

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FAQs

Osteofrac Cartridge 3 ml is used to treat Hypocalcemia.
Osteofrac Cartridge 3 ml contains Parathyroid hormone. It works by allowing the body to absorb more calcium into the blood.
Parathyroid hormone is secreted by four parathyroid glands, which are tiny glands in the neck positioned behind the thyroid gland.
The parathyroid glands generate parathyroid hormone, which is important in regulating calcium levels in the blood. Precise calcium levels are critical in the human body since even minor alterations can cause muscular and nerve issues.
Osteofrac Cartridge 3 ml therapy may increase the chances of cancer. Tell your doctor if you or a family member has or has ever had cancer. Your doctor will monitor the condition throughout the therapy and after some time.
No, Osteofrac Cartridge 3 ml is not a steroid. It contains a synthetic form of the parathyroid hormone (PTH), which helps regulate calcium levels in the blood and bone metabolism. It is primarily used to treat hypocalcaemia caused by hypoparathyroidism.
Osteofrac Cartridge 3 ml is sometimes prescribed for long-term use in osteoporosis to help build bone density. However, it can be determined by the doctor based on your medical conditions. Therefore, it is important to follow the doctor’s guidance regarding duration and monitoring.
Osteofrac Cartridge 3 ml should be stored in the refrigerator at a temperature of 2°C to 8°C. Avoid freezing, and keep them away from direct light.
Osteofrac Cartridge 3 ml should not be received if you are allergic to any of its ingredients. Individuals with Paget's disease of bone, unexplained elevated alkaline phosphatase levels, or a history of prior radiation therapy involving the skeleton. Additionally, those with severe renal impairment or who are pregnant or breastfeeding are advised to avoid using this medication.
The side effects of Osteofrac Cartridge 3 ml include headache, tingling, tickling, or burning feeling of the skin, a sense of numbness, pain in the arms, legs, joints, stomach, or neck, and diarrhoea. Consult the doctor if any of these side effects persist or worsen.

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