ORNICEF TABLET belongs to the group of 'antibacterial medications,' primarily used to treat bacterial infections. A bacterial infection is a condition in which harmful bacteria enter, multiply and infect the body. They can target any part of the body and multiply very quickly. These infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis.

ORNICEF TABLET contains an antibiotic combination, Cefixime and Ornidazole, primarily used to treat bacterial infections. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, arresting cell wall assembly resulting in bacterial cell death. Ornidazole kills other infectious microorganisms in addition to bacteria by damaging their DNA, does preventing the bacteria to reproduce or repair by themselves.

In some cases, you may experience certain common side-effects such as nausea, vomiting, loss of appetite, dizziness, tremors, headache, diarrhoea, stomach pain, flatulence. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Before starting ORNICEF TABLET, please inform your doctor if you have any allergy (against these antibiotics), kidney or liver problems. Do not take ORNICEF TABLET on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor before taking ORNICEF TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption while taking ORNICEF TABLET as it may cause increased dizziness. ORNICEF TABLET may cause dizziness and vision problems, so be cautious while driving. ORNICEF TABLET is not recommended for use in children.

ORNICEF TABLET is an antibiotic combination containing Cefixime, and Ornidazole primarily used to treat bacterial infections. Cefixime binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis, arresting cell wall assembly resulting in bacterial cell death. Ornidazole kills other infectious microorganisms in addition to bacteria by damaging their DNA, does preventing the bacteria to reproduce or repair by themselves.

• Headache
• Nausea
• Dizziness
• Diarrhoea
• Loss of appetite
• Indigestion
• Flatulence
• Stomach pain

Do not take ORNICEF TABLET if you are allergic to ORNICEF TABLET or any of its ingredients. Tell your doctor if you have liver problems (jaundice), muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), diabetes, electrolyte imbalance (low potassium or magnesium level), and kidney or liver diseases.  In rare cases, the use of ORNICEF TABLET can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking ORNICEF TABLET and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you. Maintain a minimum gap of two hours between ORNICEF TABLET and antacid, vitamin, and mineral medicines. Consult your doctor before taking ORNICEF TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption while taking ORNICEF TABLET as it causes increased dizziness. ORNICEF TABLET may cause dizziness and vision problems, so be cautious while driving. ORNICEF TABLET is not recommended for use in children unless recommended by a doctor. Also, it is recommended to complete the course of medicine even if you feel better as ORNICEF TABLET contains antibiotics, and leaving it in between may lead to even severe infection that will, in fact, stop responding to the antibiotic as well (antibiotic resistance).

Drug-Drug Interactions: ORNICEF TABLET may have interaction with pain killers (aspirin, ibuprofen), antibiotic (azithromycin, ciprofloxacin, sulfamethoxazole, trimethoprim, metronidazole, erythromycin), anti-diabetic (metformin), diuretics (furosemide),  antihistamine medicines (chlorpheniramine), blood thinners (warfarin)

Drug-Food Interactions: Eating grapefruit during antibiotics treatment can prevent the body from utilising ORNICEF TABLET properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. Avoid taking too much of calcium-enriched foods and drinks as it might affect the working of ORNICEF TABLET. Aluminium and magnesium-containing antacids, Multivitamins, multi-minerals containing zinc and iron should not be consumed along with ORNICEF TABLET; maintain a minimum gap of two hours between both.

Drug-Disease Interactions: ORNICEF TABLET may interact in patients with diabetes mellitus, renal dysfunction, liver disease, seizure disorders, colitis (bowel disease that affects the large intestine, causing irritation, inflammation, and ulcers in the colon), muscle problem (muscle weakness).

• ASPIRIN
• IBUPROFEN
• AZITHROMYCIN
• CIPROFLOXACIN
• SULFAMETHOXAZOLE
• TRIMETHOPRIM
• METRONIDAZOLE
• ERYTHROMYCIN
• METFORMIN
• FUROSEMIDE
• CHLORPHENIRAMINE

• Probiotics should be taken after taking the full course of ORNICEF TABLET to restore some of the healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yogurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria. 
• Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. 
• Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of ORNICEF TABLET. 
• Avoid intake of alcoholic beverages with ORNICEF TABLET as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the ORNICEF TABLET in fighting off infections.

• ORNICEF TABLET contains ornidazole, which may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Regularly monitor these tests if you are taking ORNICEF TABLET.
• Cefixime in ORNICEF TABLET may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunization/vaccinations while using this medication unless your doctor tells you to.

Bacterial infection: It is a condition in which harmful bacteria enter, multiply, and infect the body. They can target any part of the body and multiply very quickly. These infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. When you get infected with these germs, you can experience generalized symptoms, like fevers, chills and fatigue. Few harmful bacteria that commonly cause infections include Streptococcus, Staphylococcus and E. coli. Anyone can get a bacterial infection, but people with a weak immune system or taking immunosuppressive medicines like steroids are more prone to infections.