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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:52 PM IST
Olmat-40 H Tablet is used to treat high blood pressure (hypertension). It contains Olmesartan medoximil and Hydrochlorothiazide, which relaxes and widens the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Also, it removes extra water/fluid and certain electrolyte overload from the body. In some cases, you may experience side effects such as nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness, and decreased blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer

Micro Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Olmat-40 H Tablet

Olmat-40 H Tablet belongs to a group of medications called 'anti-hypertensives' primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Olmat-40 H Tablet is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Olmat-40 H Tablet lowers blood pressure and fluid overload.

You can take Olmat-40 H Tablet with food or without food with a glass of water. Do not chew, bite, or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness, and decreased blood pressure. Most of these side effects of Olmat-40 H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Olmat-40 H Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark colour urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, or heart disease or are diabetic. If you are pregnant or breastfeeding, do not take Olmat-40 H Tablet as it is a category D pregnancy drug and may harm the baby. Do not use Olmat-40 H Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), and have or have had cardiogenic shock (sudden stopping of blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine.

Uses of Olmat-40 H Tablet

Treatment of Hypertension (high blood pressure)

Medicinal Benefits

Olmat-40 H Tablet is primarily used to treat high blood pressure. Olmat-40 H Tablet is a combination of two medicines: Olmesartan and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin and relaxes blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Hydrochlorothiazide (diuretic or water pill); removes extra water and certain electrolytes from the body. Together, both lower fluid overload, and blood pressure, improve blood flow and reduce the future risk of a heart attack.

Directions for Use

Swallow the medicine as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Olmat-40 H Tablet

  • Stuffy nose/sore throat
  • Nausea
  • Upset stomach
  • Headache
  • High level of uric acid
  • Diarrhoea
  • Electrolyte imbalance
  • Dehydration
  • Dizziness
  • Decreased blood pressure

Drug Warnings

Do not use Olmat-40 H Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Olmat-40 H Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Olmat-40 H Tablet may pass into breast milk, so before starting Olmat-40 H Tablet , either you need to stop nursing, or you should not take Olmat-40 H Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Olmat-40 H Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Olmat-40 H Tablet to avoid any electrolyte imbalance. 

Drug Interactions

Drug-Drug Interactions: This medicine may interact with an antidepressant (lithium), heart rhythm-controlling medicines (digoxin), blood thinner (aspirin), antidiabetic medicines (metformin, insulin), medicines used to treat erectile dysfunction (sildenafil), medicines used to lower cholesterol levels (simvastatin), immunosuppressants (cyclosporine), and other anti-hypertensive medicines (atenolol, aliskiren, enalapril, lisinopril, ramipril, metoprolol), pain killers (ibuprofen), medicines for treating stomach ulcers (carbenoxolone).

Drug-Food Interactions: Olmat-40 H Tablet may interact with high potassium-containing food and drinks. So, if you are using any of the OTC items, please tell your doctor. Also, alcohol should not be consumed while taking Olmat-40 H Tablet .

Drug-Disease Interactions: The efficacy of Olmat-40 H Tablet is affected, and the disease condition may even worsen if taken in patients with a recent or history of heart attack, low blood pressure, low potassium level, low electrolytes (sodium, potassium, calcium, etc.), anuria (non-passage of urine), angioedema (an allergic condition with swelling under the skin), lupus (an autoimmune disease), kidney disease, liver disease, asthma, diabetes.

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • ASPIRIN
  • METFORMIN
  • INSULIN
  • SILDENAFIL
  • SIMVASTATIN
  • CYCLOSPORINE
  • ATENOLOL
  • ALISKIREN
  • LISINOPRIL
  • RAMIPRIL
  • METOPROLOL
  • IBUPROFEN
  • CARBENOXOLONE

Habit Forming

No

Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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Alcohol

Unsafe

You are recommended not to consume alcohol and Olmat-40 H Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Caution

Olmat-40 H Tablet is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Caution

Olmat-40 H Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding for using Olmat-40 H Tablet , or you need to stop takingOlmat-40 H Tablet .

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Driving

Unsafe

Drive with caution. Olmat-40 H Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Olmat-40 H Tablet to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Caution

Olmat-40 H Tablet to be taken with caution, especially if you have a kidney disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Caution

Efficacy and safety of Olmat-40 H Tablet have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - OLM0046

Author Details

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FAQs

Olmat-40 H Tablet is used to treat high blood pressure (hypertension), a chronic condition in which the blood's force against the artery wall is high.
Olmat-40 H Tablet is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Olmat-40 H Tablet lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.
Yes, Olmat-40 H Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Olmat-40 H Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
It's unlikely that Olmat-40 H Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
In case you have missed a dose of Olmat-40 H Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Olmat-40 H Tablet will lead to low blood pressure.
Olmat-40 H Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Olmat-40 H Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in future.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Please inform your doctor before surgery if you are taking Olmat-40 H Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
Do not use Olmat-40 H Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Olmat-40 H Tablet with other blood pressure-lowering pills like 'aliskiren' immediately stop taking both together and consult a doctor.
Olmat-40 H Tablet may start to lower blood pressure within a few days to a week, but its full effect is usually reache after 2 to 8 weeks of use. Therefore, continue using Olmat-40 H Tablet for the prescribed duration to treat your condition effectively.
Your doctor may recommend taking your first dose of Olmat-40 H Tablet before bedtime, as it can cause dizziness. After the initial dose, you can take it at any time of day. While most people take it in the morning, the timing isn't critical—just aim to take it at the same time each day.
Dizziness is a common side effect of Olmat-40 H Tablet . Avoid driving or operating machinery if you experience dizziness.
While taking Olmat-40 H Tablet , it’s helpful to make lifestyle changes that can improve both your blood pressure and your overall health. Try to maintain a healthy weight, get at least 30 minutes of exercise each day, and eat a balanced diet that includes plenty of whole grains, fruits, vegetables, and low-fat dairy. Reduce your sodium and alcohol intake, and avoid smoking. To manage stress, consider mindfulness practices and stay connected with supportive friends or family. Regularly check your blood pressure, and include omega-3-rich foods in your diet. For cooking, choose healthier oils like olive, canola, soybean, or coconut oil.
Olmat-40 H Tablet may cause weight gain in some people, but it's not common. This may happen because the medication can lead to fluid retention, higher sodium levels, or increased appetite. If you notice significant weight gain, it's a good idea to talk to your doctor for advice.
In rare cases, Olmat-40 H Tablet may cause serious side effects like bladder pain, bloating, blurred vision, chest pain, increased urination, or unusual weight gain or loss. While not everyone experiences these side effects, if they do occur, you should consult your doctor immediately.
It's unlikely that Olmat-40 H Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
Take Olmat-40 H Tablet exactly as your doctor has instructed to manage your high blood pressure (hypertension). Since this is a long-term treatment, it's important to take it regularly as prescribed. Be sure to have regular check-ups with your doctor to track your blood pressure, adjust your dosage if needed, and ensure that the medication is working well for you. By sticking to your doctor's advice and attending follow-up appointments, you can better control your blood pressure and reduce the risk of complications.
You can take Olmat-40 H Tablet with or without food as advised by the doctor. Swallow it as a whole with water.
Common side effects of Olmat-40 H Tablet include a stuffy nose, sore throat, nausea, upset stomach, headache, high uric acid levels, diarrhoea, electrolyte imbalances, dehydration, dizziness, and low blood pressure. These side effects typically don’t need medical attention and usually improve over time. However, if they persist or worsen, it's important to consult your doctor.
Olmat-40 H Tablet is not recommended during pregnancy, as it is classified as a Category D medication. This means it may harm the foetus and could cause damage to the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor about alternative treatments.
Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.
Olmat-40 H Tablet should be stored in a cool and dry place away from the sunlight. Keep it out reach from children and pets.

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