Ofrise-OZ Tablet belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults.

Ofrise-OZ Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase, which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Ofrise-OZ Tablet helps in treating bacterial infections.

Take Ofrise-OZ Tablet as prescribed. In some cases, Ofrise-OZ Tablet may cause side effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Talk to your doctor if you experience pain in tendons, swelling, and inflammation as Ofrise-OZ Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor before taking Ofrise-OZ Tablet if you are pregnant or breastfeeding. Ofrise-OZ Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Ofrise-OZ Tablet as it may cause increased dizziness. Ofrise-OZ Tablet is not recommended for use in children.

Ofrise-OZ Tablet belongs to the group of medicines called antibiotics used to treat urinary tract infections, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults. Ofrise-OZ Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase, which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby killing the bacteria. Together, Ofrise-OZ Tablet helps in treating bacterial infections. Ofrise-OZ Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

• Nausea
• Vomiting
• Abdominal pain
• Headache
• Dizziness

Do not take Ofrise-OZ Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics; or if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor before taking Ofrise-OZ Tablet if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes, rheumatoid arthritis, multiple sclerosis, heart, kidney or liver problems. Consult your doctor before taking Ofrise-OZ Tablet if you are pregnant or breastfeeding. Ofrise-OZ Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Ofrise-OZ Tablet as it may cause increased dizziness.

Drug-Drug Interactions: Ofrise-OZ Tablet may interact with pain killers (aspirin, ibuprofen), antibiotics (azithromycin, sulfamethoxazole, trimethoprim, metronidazole, erythromycin), corticosteroids (dexamethasone), anti-diabetic (metformin), bronchodilator (albuterol), and diuretics (furosemide).

Drug-Food Interactions: Avoid consuming milk and dairy products.

Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), tendonitis (inflammation in tendons), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), crystalluria (cloudy urine), diabetes, kidney, liver and heart problems.

• ASPIRIN
• IBUPROFEN
• AZITHROMYCIN
• TRIMETHOPRIM+SULFAMETHOXAZOLE
• METRONIDAZOLE
• ERYTHROMYCIN
• DEXAMETHASONE
• METFORMIN
• ALBUTEROL
• FUROSEMIDE

• Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.

• Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.

• Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.

• Avoid consumption of alcohol and usage of tobacco.

• Ofrise-OZ Tablet may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Ofrise-OZ Tablet contains ofloxacin which might produce false-positive urine screening results for opiates. Inform the person doing the tests that you are taking Ofrise-OZ Tablet .

• Ofrise-OZ Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Ofrise-OZ Tablet .

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. It can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

Diarrhoea: Diarrhoea is the condition in which there is a frequent need to empty the bowels. It is characterized by loose and watery stools. The causes of diarrhoea include food intolerance, food allergy, adverse reaction to any medicine, viral infection, bacterial infection, intestinal disease, parasitic infection, and stomach or gallbladder surgery. The symptoms of diarrhoea include nausea, abdominal pain/cramps, dehydration, bloating, frequent urge to empty the bowels, and a large volume of stools or watery stools.