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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Nitroderm TTS 5 Transdermal Patch belongs to the class of anti-anginal drugs, which is used in the treatment of angina pectoris. It works by relaxing the blood vessels and thus helps boost blood supply to the heart. Some of the common side effects include headache, hypotension, dizziness, light-headedness, and blurred vision.
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Manufacturer/Marketer :

Novartis India Ltd

Consume Type :

TOPICAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Nitroderm TTS 5 Transdermal Patch

Nitroderm TTS 5 Transdermal Patch belongs to the class of anti-anginal medication primarily used to prevent angina pectoris due to coronary artery disease. It can be used as monotherapy or in combination with other anti-anginal agents. Angina occurs when the heart does not get a sufficient amount of blood.

Nitroderm TTS 5 Transdermal Patch contains glyceryl trinitrate, a natural vasodilator that works by relaxing the blood vessels (veins and arteries). This boosts the blood supply to the heart, allowing more oxygen to reach the heart muscles and reducing chest pain. Thus, it prevents angina.

Use Nitroderm TTS 5 Transdermal Patch exactly as prescribed by the healthcare professional. Sometimes, Nitroderm TTS 5 Transdermal Patch may cause nausea, vomiting, headache, and application site reactions such as redness, itching or burning sensation. Most of these side effects are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Nitroderm TTS 5 Transdermal Patch, if you are pregnant, suspect you are pregnant, planning pregnancy, or if you are breastfeeding. Notify your doctor if you are wearing a patch (Nitroderm TTS 5 Transdermal Patch) before an MRI scan, diathermy treatment (treatment using hot wires) and before electrical therapy on the heart. Avoiding alcohol is recommended to rule out possible side effects like fainting or dizziness. 

Uses of Nitroderm TTS 5 Transdermal Patch

Treatment of Angina pectoris

Directions for Use

Transdermal patch: Apply the patch to the clean and dry area of the skin as advised by a doctor.Ointment/Cream: It is only for external use. Take a small amount of the ointment/cream on the fingertip and apply it as a thin layer on the clean and dry chest area as prescribed by your doctor. Avoid contact of this medicine with your nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Nitroderm TTS 5 Transdermal Patch contains Glyceryl trinitrate, a natural vasodilator primarily used to prevent angina pectoris due to coronary artery disease. Nitroderm TTS 5 Transdermal Patch works by relaxing the muscles surrounding blood vessels, making the heart's job easier. Nitroderm TTS 5 Transdermal Patch provides a non-invasive and painless way of medication delivery, with the added benefit of providing a consistent therapeutic dosage over a set time period.

How Nitroderm TTS 5 Transdermal Patch Works

Nitroderm TTS 5 Transdermal Patch contains glyceryl trinitrate, a natural vasodilator that works by relaxing the blood vessels (veins and arteries). This boosts the blood supply to the heart, allowing more oxygen to reach the heart muscles and reducing chest pain. Thus, it prevents angina.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nitroderm TTS 5 Transdermal Patch

  • Nausea
  • Vomiting
  • Headache
  • Application site reactions (redness, itching or burning sensation)

What if I have taken an overdose of Nitroderm TTS 5 Transdermal Patch

Use Nitroderm TTS 5 Transdermal Patch as directed by your doctor. An overdose may cause shortness of breath, Slow breathing, blurred vision, double vision, involuntary eye movements, and an inability to feel a heartbeat (palpitations). If you experience any of these symptoms, seek emergency medical help.

Drug Warnings

Inform your doctor if you are allergic to any of the components in Nitroderm TTS 5 Transdermal Patch. Do not use Nitroderm TTS 5 Transdermal Patch if you take any medication for erectile dysfunction (male impotence). It is not recommended to take Nitroderm TTS 5 Transdermal Patch if you have headache, vomiting or seizures due to raised pressure inside the skull. Please check with your doctor before using Nitroderm TTS 5 Transdermal Patch if you have/had anaemia, low blood pressure, stroke, head injury, heart, kidney, liver or lung disease. Before starting Nitroderm TTS 5 Transdermal Patch, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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Glyceryl trinitrateMethylergometrine
Critical
Glyceryl trinitrateVardenafil
Critical

Drug-Drug Interactions

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Glyceryl trinitrateMethylergometrine
Critical
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Methylergometrine with Nitroderm TTS 5 Transdermal Patch can increase the levels and side effects of Methylergometrine.

How to manage the interaction:
Taking Methylergometrine with Nitroderm TTS 5 Transdermal Patch is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, headache, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateVardenafil
Critical
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Taking Vardenafil and Nitroderm TTS 5 Transdermal Patch together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Vardenafil and Nitroderm TTS 5 Transdermal Patch is generally avoided as it can lead to an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateAvanafil
Critical
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Taking Avanafil and Nitroderm TTS 5 Transdermal Patch together can increase the risk or severity of low blood pressure.

How to manage the interaction:
Combining Avanafil and Nitroderm TTS 5 Transdermal Patch is generally avoided as it can lead to an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity), consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateChloroprocaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Chloroprocaine and Nitroderm TTS 5 Transdermal Patch can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Chloroprocaine and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateTetracaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Tetracaine and Nitroderm TTS 5 Transdermal Patch has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Tetracaine and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateMepivacaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Mepivacaine and Nitroderm TTS 5 Transdermal Patch has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Mepivacaine and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateEtidocaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Etidocaine and Nitroderm TTS 5 Transdermal Patch can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Etidocaine and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discoloration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateLevobupivacaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Levobupivacaine and Nitroderm TTS 5 Transdermal Patch can increase the risk of developing methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Levobupivacaine and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting your doctor.
Glyceryl trinitrateSodium nitrite
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of Sodium nitrite and Nitroderm TTS 5 Transdermal Patch has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Sodium nitrite and Nitroderm TTS 5 Transdermal Patch together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without first consulting your doctor.
Glyceryl trinitrateBupivacaine
Severe
How does the drug interact with Nitroderm TTS 5 Transdermal Patch:
Coadministration of bupivacaine and Nitroderm TTS 5 Transdermal Patch can increase the risk and severity of developing methemoglobinemia, (Red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Nitroderm TTS 5 Transdermal Patch together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Consume low salt and a low-fat diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption.
  • Choose healthy fats and cut down on trans fat.
  • Include omega-3 fatty acids, fibre-rich food, fruits, and vegetables.
  • Get active by doing physical activities such as swimming, brisk walking, or jogging. Take the stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

ANTIANGINALS
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Alcohol

Unsafe

Concomitant use of nitrates and alcohol may cause hypotension. So intake of alcohol should be avoided with Nitroderm TTS 5 Transdermal Patch.

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Pregnancy

Caution

Inform your doctor if you are pregnant or planning pregnancy before using this Nitroderm TTS 5 Transdermal Patch. Your doctor will weigh the benefits and potential risks before prescribing Nitroderm TTS 5 Transdermal Patch.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother before using this Nitroderm TTS 5 Transdermal Patch. Your doctor will weigh the benefits and potential risks before prescribing Nitroderm TTS 5 Transdermal Patch.

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Driving

Caution

Nitroderm TTS 5 Transdermal Patch may cause dizziness. So, driving vehicles and operating machinery which requires concentration should be avoided.

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Liver

Caution

Inform your doctor before using Nitroderm TTS 5 Transdermal Patch if you have liver problems or a history of liver conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor before using Nitroderm TTS 5 Transdermal Patch if you have kidney problems or a history of kidney conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

The safety and effectiveness of Nitroderm TTS 5 Transdermal Patch in children have not been established.

FAQs

Nitroderm TTS 5 Transdermal Patch belongs to the class of anti-anginal medication primarily used to prevent angina pectoris due to coronary artery disease. It can be used as monotherapy or in combination with other anti-anginal agents.
Nitroderm TTS 5 Transdermal Patch relaxes the muscles surrounding blood vessels, making the heart's job easier. When used on a regular and long-term basis, this helps to prevent angina episodes.
Patients may benefit from Nitroderm TTS 5 Transdermal Patch over oral formulations in terms of convenience of administration, easy treatment regimes, and avoidance of the first-pass and peak dosage effects.
No, you should not combine Nitroderm TTS 5 Transdermal Patch with an erectile dysfunction medicine such as sildenafil, vardenafil, or tadalafil since it may interfere with the blood pressure-lowering action of Nitroderm TTS 5 Transdermal Patch.
Yes, headache is the most common side effect encountered while using Nitroderm TTS 5 Transdermal Patch. Please drink more fluids if you have headache. If the problem persists, consult your doctor.
It is recommended not to use Nitroderm TTS 5 Transdermal Patch in patients with hypotension (low blood pressure); inform your doctor before using Nitroderm TTS 5 Transdermal Patch if you have ever had hypotension.
You may be prescribed antianginal drugs when patches are not adequate to prevent angina attacks. However, take antianginal drugs in addition to patches only if prescribed by your doctor.
It is recommended not to use Nitroderm TTS 5 Transdermal Patch in patients with severe anaemia (doesn't have enough healthy red blood cells); inform your doctor before using Nitroderm TTS 5 Transdermal Patch if you have ever had anaemia.

Country of origin

Switzerland

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - NIT0011

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