Nicoduce 48mg Injection belongs to a class of medication called 'vasodilators' used to prevent or treat angina pectoris (heart-related chest pain) in adults who cannot take beta-blockers (blood pressure-lowering pills). Angina pectoris is a kind of chest pain due to decreased blood flow to the heart. It is a symptom of coronary artery disease.

Nicoduce 48mg Injection contains Nicorandil, a potassium-channel activator that opens potassium channels present on the muscle cells within the walls of blood vessels and relaxes these muscle cells and widens blood vessels. Thereby, Nicoduce 48mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicoduce 48mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart.

Nicoduce 48mg Injection will be administered by a healthcare professional; do not self-administer. Some people may experience headache, nausea, vomiting, dizziness, weakness or flushing (reddening of the skin). Most of these side effects of Nicoduce 48mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

If you are allergic to Nicorandil or any other medicines, inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Nicoduce 48mg Injection. Drive only if you are alert as Nicoduce 48mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicoduce 48mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicoduce 48mg Injection as it may affect blood pressure.

Nicoduce 48mg Injection contains Nicorandil, a potassium-channel activator used to prevent or treat angina pectoris (chest pain). Nicoduce 48mg Injection works by opening potassium channels present on the muscle cells within the blood vessels' walls and relaxing these muscle cells and widening blood vessels. Thereby, Nicoduce 48mg Injection reduces the heart's workload by making it easier for the heart to pump blood around the body and does not require much oxygen. Also, Nicoduce 48mg Injection helps to prevent angina by increasing oxygen and blood supply to the heart muscle by widening coronary arteries within the heart. Nicoduce 48mg Injection is given to adults who cannot tolerate other heart medicines such as calcium antagonists or beta-blockers. 

• Headache
• Nausea
• Vomiting
• Dizziness
• Weakness
• Flushing (reddening of the skin)

If you are allergic to Nicorandil or any other medicines, please tell your doctor. Avoid taking Nicoduce 48mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (accumulation of fluid in the lungs) or any heart problems. If you are pregnant or breastfeeding, please consult a doctor. Nicoduce 48mg Injection is not recommended for children as safety and effectiveness were not established. Drive only if you are alert as Nicoduce 48mg Injection may cause dizziness or weakness. Avoid alcohol consumption with Nicoduce 48mg Injection as it may cause severely low blood pressure. Avoid taking vardenafil, sildenafil, tadalafil and riociguat with Nicoduce 48mg Injection as it may affect blood pressure. If you notice in blood in stools while taking Nicoduce 48mg Injection, inform your doctor immediately as it may be due to ulcers in the stomach, intestines or back passage. 

Drug-Drug Interaction: Nicoduce 48mg Injection may interact with medicines used to treat erectile dysfunction (vardenafil, sildenafil, tadalafil), drugs to treat pulmonary hypertension (riociguat), medicine to treat premature ejaculation (dapoxetine), pain reliever (aspirin), steroids (prednisolone), high blood pressure-lowering medicines (lisinopril, ramipril, losartan, valsartan, candesartan).

Drug-Food Interaction: Nicoduce 48mg Injection may interact with alcohol. Therefore, avoid alcohol intake while taking Nicoduce 48mg Injection as it may cause severe low blood pressure.

Drug-Disease Interaction: Avoid taking Nicoduce 48mg Injection if you have hypotension (severe low blood pressure), low blood volume, pulmonary oedema (build-up of fluid in the lungs) or any heart problems.

• VARDENAFIL
• SILDENAFIL
• TADALAFIL
• RIOCIGAUT
• DAPOXETINE
• ASPIRIN
• PREDNISOLONE
• LISINOPRIL
• RAMIPRIL
• LOSARTAN
• VALSARTAN
• CANDESARTAN

• Follow a cholesterol-lowering diet.
• Consume low-salt and a low-fat diet.
• Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
• Limit salt and sugar intake.
• Avoid smoking and alcohol consumption.
• Choose healthy fats and cut down on trans fat.
• Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
• Get active by doing any physical activity such as swimming, brisk walking or jogging. Take the stairs instead of elevators/lifts.

Angina pectoris: Angina pectoris is a type of chest pain caused by decreased blood flow to the heart, resulting in inadequate oxygen supply to the heart muscle. Emotional stress or physical activity are common causes of chest pain. Angina is a sign that you have coronary artery disease. Angina symptoms include dizziness, shortness of breath, nausea, fatigue, anxiety, or excessive sweating. Smoking, diabetes, being overweight, high blood pressure, high cholesterol, not exercising, or a family history of heart disease are all risk factors for angina.