Nesprex 20mg Tablet DT used to relieve symptoms like pain, inflammation and joint stiffness associated with rheumatoid arthritis and osteoarthritis. Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering (cartilage). Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage.

Nesprex 20mg Tablet DT contains 'Piroxicam' that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

Take Nesprex 20mg Tablet DT as prescribed. In some cases, you may experience certain common side effects, such as diarrhoea, dizziness, nausea, vomiting, and stomach pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to speak to your doctor if you experience these side effects persistently.

Nesprex 20mg Tablet DT can increase your risk of a fatal heart attack or stroke. So, if you have had any recent heart bypass surgery, do not take Nesprex 20mg Tablet DT unless prescribed by the doctor. Nesprex 20mg Tablet DT increases the chances of stomach ulcers and bleeding. Consult your doctor before taking Nesprex 20mg Tablet DT if you are pregnant or breastfeeding. Nesprex 20mg Tablet DT may cause dizziness, so drive with caution. Nesprex 20mg Tablet DT is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol along with Nesprex 20mg Tablet DT as it could lead to increased dizziness. It could also increase the risk of stomach bleeding.

Nesprex 20mg Tablet DT belongs to the group of painkillers known as NSAIDs (Non-Steroidal Anti-Inflammatory Drugs). Nesprex 20mg Tablet DT is used to relieve symptoms associated with osteoarthritis, and rheumatoid arthritis, such as stiffness, swelling, and joint pain. Nesprex 20mg Tablet DT works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.

• Diarrhoea
• Dizziness
• Nausea
• Vomiting
• Stomach pain

Nesprex 20mg Tablet DT may increase the risk of serious heart-related problems, like heart attack and stroke. So, if you are a heart patient, let your doctor know before taking Nesprex 20mg Tablet DT. Besides this, Nesprex 20mg Tablet DT may also cause stomach and intestinal bleeding/ulcers, so let your doctor know if you have these problems. Do not take Nesprex 20mg Tablet DT if you have had heart bypass surgery or coronary artery bypass graft surgery (CABG) as it can increase your risk of a heart attack or stroke. Consult your doctor before taking Nesprex 20mg Tablet DT if you are pregnant or breastfeeding. Nesprex 20mg Tablet DT may cause drowsiness and dizziness, so drive only if you are alert. Nesprex 20mg Tablet DT is not recommended for children as safety has not been established. Avoid consuming alcohol along with Nesprex 20mg Tablet DT as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Tell your doctor before taking Nesprex 20mg Tablet DT if you have asthma, water retention (oedema) or high blood pressure, stuff/runny nose, nasal polyps, liver or kidney problems.

Drug-Drug Interactions: Nesprex 20mg Tablet DT may have interaction with anti-depressants (duloxetine, sertraline), anti-hypertensives (metoprolol), drugs used to treat arthritis (celecoxib).

Drug-Food Interactions: Avoid consuming alcohol along with Nesprex 20mg Tablet DT as it could lead to increased drowsiness and dizziness. It could also lead to an increase in the risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have/had heart failure, fluid retention (oedema), asthma, gastrointestinal ulcer/bleeding, high blood pressure, hyperkalemia (high levels of potassium), thrombosis (formation of clots), anaemia (low red blood cells), rash, platelet aggregation inhibition, kidney and liver problems.

• DULOXETINE
• SERTRALINE
• METOPROLOL
• CELECOXIB

• Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.

• Performing yoga may also help in improving joint flexibility and pain management.

• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

• Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.

• Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.

• De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.

• Acupuncture, massage, and physical therapy may also be helpful.

• Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

• Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

• Avoid smoking and alcohol consumption.

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons might include a past injury such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function.