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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:49 PM IST
Navtil 5mg Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere's disease. It contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre, thereby preventing nausea and vomiting. Besides this, it also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. It may cause side effects such as dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Navtil 5mg Tablet

Navtil 5mg Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness. 

Navtil 5mg Tablet contains Prochlorperazine, which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, Navtil 5mg Tablet also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. 

Take Navtil 5mg Tablet as prescribed by your doctor. You are advised to take Navtil 5mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling.  Most of these side effects of Navtil 5mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Navtil 5mg Tablet if you are known to be allergic to Navtil 5mg Tablet. Navtil 5mg Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Navtil 5mg Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Navtil 5mg Tablet is not recommended for children below 1 year of age. Avoid exposure to direct sunlight while taking Navtil 5mg Tablet as it may cause the skin to be more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Navtil 5mg Tablet.

Uses of Navtil 5mg Tablet

Treatment of Nausea and vomiting in migraine, Schizophrenia, Anxiety disorder.

Medicinal Benefits

Navtil 5mg Tablet contains Prochlorperazine, which inhibits dopamine secretion that induces the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Navtil 5mg Tablet prevents nausea and vomiting. Also, Navtil 5mg Tablet controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Avoid contact of tablet with your skin for a very long time as it may cause swelling, skin redness, and itching (contact skin sensitization).Tablet MD: Place the mouth-dissolving tablet in the mouth and allow it to dissolve. Do not swallow. Avoid handling the tablets with wet hands.Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Navtil 5mg Tablet

  • Dry mouth

  • Drowsiness
  • Headache
  • Dizziness
  • Stuffy nose
  • Irritability
  • Missed menstrual periods
  • Impotence (difficulty in maintaining an erection)
  • Anxiety
  • Skin rash
  • Skin redness, itching or swelling

Drug Warnings

Do not take Navtil 5mg Tablet if you are known to be allergic to Navtil 5mg Tablet. Navtil 5mg Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Navtil 5mg Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Navtil 5mg Tablet is not recommended for children below 1 year of age. Avoid consumption of alcohol with Navtil 5mg Tablet as it may increase adverse effects. You are recommended to avoid contact of Navtil 5mg Tablet with the skin for a long time as it may cause swelling, redness or itching of the skin. Avoid exposure to direct sunlight while taking Navtil 5mg Tablet as it may cause skin to more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Navtil 5mg Tablet.

Drug Interactions

Drug-Drug Interaction: Navtil 5mg Tablet may have interaction with high blood pressure-lowering medicines (metoprolol), opioid analgesics (fentanyl, hydrocodone), laxative (polyethylene glycol 3350), anticonvulsants (pregabalin), antihistamines (diphenhydramine), anti-anxiety drugs (lorazepam, alprazolam), antidepressants (duloxetine), anti-sickness drug (ondansetron).

Drug-Food Interaction: Avoid the intake of alcohol while taking Navtil 5mg Tablet as it may increase side effects and cause breathing difficulties.

Drug-Disease Interaction: If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Navtil 5mg Tablet.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • FENTANYL
  • HYDROCODONE
  • POLYETHYLENE GLYCOL
  • PREGABALIN
  • DIPHENHYDRAMINE
  • LORAZEPAM
  • ALPRAZOLAM
  • DULOXETINE
  • ONDANSETRON

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.

  • If you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.

  • Include more cool beverages in your food like flavoured gelatin, carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.

  • Drink any other liquid at least 30 minutes after eating food.

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.

  • Avoid consumption of alcohol as it may increase adverse effects.

Special Advise

Avoid exposure to direct sunlight while taking Navtil 5mg Tablet as it may cause the skin to be more sensitive to sunlight.

Disease/Condition Glossary

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. The anxiety symptoms include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.

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Alcohol

Unsafe

Avoid consumption of alcohol with Navtil 5mg Tablet as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Unsafe

Navtil 5mg Tablet is a Category C pregnancy drug. It is not recommended for use during pregnancy, especially in the third trimester as it may cause adverse effects in the baby such as breathing problems, drowsiness, shaking, muscle stiffness or weakness. However, please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Please consult a doctor if you are a breastfeeding mother as Navtil 5mg Tablet may not be safe to use in breastfeeding mothers.

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Driving

Caution

Navtil 5mg Tablet may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Navtil 5mg Tablet.

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Liver

Caution

Take Navtil 5mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Navtil 5mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Navtil 5mg Tablet may be given to children above 1 year of age if prescribed by a doctor.

Country of origin

India
Other Info - NA94237

Author Details

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FAQs

Navtil 5mg Tablet is used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome.
Navtil 5mg Tablet contains Prochlorperazine, an antipsychotic drug that works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Navtil 5mg Tablet prevents nausea and vomiting. Also, Navtil 5mg Tablet decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia.
Yes, Navtil 5mg Tablet may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).
Navtil 5mg Tablet may cause photosensitivity (extreme sensitivity to sunlight). Therefore, it is recommended to avoid exposure to direct sunlight while taking Navtil 5mg Tablet.
You are not recommended to take Navtil 5mg Tablet with alprazolam as co-administration of these medicines may increase adverse effects such as confusion, drowsiness, dizziness and difficulty in concentrating. However, please contact your doctor before using Navtil 5mg Tablet with other medicines.
Navtil 5mg Tablet should be used with caution in diabetes patients as it may cause an increase in blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Navtil 5mg Tablet if you are diabetic.
Navtil 5mg Tablet may cause skin redness, itching and swelling if it comes in contact with the skin for a long time. Therefore, avoid contact of Navtil 5mg Tablet with the skin for a long time as it may cause contact skin sensitization.
Yes, Navtil 5mg Tablet does expire. Please verify the expiry date on the pack and it refers to the last day of that month. Navtil 5mg Tablet should not be used after the expiry date.
No, Navtil 5mg Tablet is not available over the counter. It is a prescription medication. Because it contains prochlorperazine, which can have significant side effects and requires medical supervision.
Navtil 5mg Tablet is generally safe to use when taken as prescribed by your doctor. Do not exceed the recommended daily dose. It's important to follow your doctor's instructions.
You can take Navtil 5mg Tablet for as long as it is advised by your doctor. If you have any difficulty while taking Navtil 5mg Tablet, please consult your doctor.
No, Navtil 5mg Tablet is not known to be addictive. However, it's important to use Navtil 5mg Tablet only as prescribed by your doctor and not to exceed the recommended dosage.
The common side effects of Navtil 5mg Tablet are dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling. If any of these side effects persist or worsen, please consult your doctor.

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