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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:36 PM IST
Midazom 0.5 Nasal Spray 50 mdi is used to treat Seizure clusters (acute repetitive seizures). It contains Midazolam, which increases GABA activity (a chemical messenger in the brain). Thus, it suppresses the excessive and abnormal activity of nerve cells in the brain and controls Seizures. Common side effects of Midazom 0.5 Nasal Spray 50 mdi are headache, drowsiness, runny nose, throat irritation, and nasal discomfort.
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Composition

MIDAZOLAM-0.5MG

Manufacturer/Marketer

Mindneuro Pharma

Consume Type

NASAL

Return Policy

Not Returnable

Expires on or after

Jan-26

for this medicine

About Midazom 0.5 Nasal Spray 50 mdi

Midazom 0.5 Nasal Spray 50 mdi belongs to a class of drugs called benzodiazepines used for the short-term treatment of seizure clusters. Seizure clusters are episodes of elevated seizure activity, defined as two or more seizures occurring within a 24-hour period. They are upsetting situations that can leave you feeling anxious, frustrated, or helpless.

Midazom 0.5 Nasal Spray 50 mdi contains Midazolam which works by increasing GABA activity (a chemical messenger in the brain). Thus, Midazom 0.5 Nasal Spray 50 mdi suppresses the excessive and abnormal activity of nerve cells in the brain and controls fits.

Use Midazom 0.5 Nasal Spray 50 mdi as prescribed and for the duration as your doctor has prescribed it for you based on your medical condition. Sometimes, it may cause side effects such as headache, drowsiness, runny nose, throat irritation, and nasal discomfort. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant, planning for pregnancy or are breastfeeding, please inform your doctor before taking Midazom 0.5 Nasal Spray 50 mdi. Midazom 0.5 Nasal Spray 50 mdi is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid consumption of alcohol with Midazom 0.5 Nasal Spray 50 mdi as it may cause increased drowsiness. Avoid driving or operating machinery until you know how Midazom 0.5 Nasal Spray 50 mdi affects you. Avoid using Midazom 0.5 Nasal Spray 50 mdi if you have acute narrow-angle glaucoma (eye problem). Do not take Midazom 0.5 Nasal Spray 50 mdi with opioids until and unless prescribed by a doctor, as it may increase the risk of breathing problems, severe drowsiness or coma.

Uses of Midazom 0.5 Nasal Spray 50 mdi

Treatment of Seizure clusters (acute repetitive seizures)

Medicinal Benefits

Midazom 0.5 Nasal Spray 50 mdi contains Midazolam used to treat acute (sudden) repetitive fits. Midazom 0.5 Nasal Spray 50 mdi increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thus, it suppresses the excessive and abnormal activity of nerve cells in the brain and controls fits.

Directions for Use

Insert the tip of the bottle into a nostril while closing the other nostril and spray towards the sides of the nostril. Keep your head straight and breathe gently.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Midazom 0.5 Nasal Spray 50 mdi

  • Headache
  • Drowsiness
  • Runny nose
  • Throat irritation
  • Nasal discomfort

Drug Warnings

If you are allergic to Midazolam or any other medicines, please tell your doctor. If you are pregnant, planning for pregnancy, or breastfeeding, please inform your doctor before using Midazom 0.5 Nasal Spray 50 mdi. Midazom 0.5 Nasal Spray 50 mdi is not recommended for children below 12 years as the safety and effectiveness were not established. Avoid consumption of alcohol with Midazom 0.5 Nasal Spray 50 mdi as it may cause drowsiness. Avoid driving or operating machinery until you know how Midazom 0.5 Nasal Spray 50 mdi affects you. Avoid using Midazom 0.5 Nasal Spray 50 mdi if you have acute narrow-angle glaucoma (eye problem). Do not take Midazom 0.5 Nasal Spray 50 mdi with opioids until and unless prescribed by a doctor, as it may increase the risk of breathing problems, severe drowsiness or coma. Get medical help immediately if you experience unusually excessive sleepiness or shallow or slowed breathing while using Midazom 0.5 Nasal Spray 50 mdi.

Drug Interactions

Drug-Drug Interaction: Inform your doctor about all the other medicines you are taking, including prescription and over-the-counter medicines and herbal and vitamin supplements.

Drug-Food Interaction: Avoid alcohol consumption with Midazom 0.5 Nasal Spray 50 mdi as it may increase drowsiness or dizziness.

Drug-Disease Interaction: Avoid using Midazom 0.5 Nasal Spray 50 mdi if you have acute narrow-angle glaucoma (eye problem). If you have a history of drug abuse, mood problems, depression, suicidal thoughts or behaviour, asthma, bronchitis, chronic obstructive pulmonary disease or other breathing problems, kidney, liver or heart problems, inform your doctor before taking Midazom 0.5 Nasal Spray 50 mdi.

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercise and maintain a healthy body weight.
  • Maintain a diet rich in fruits, vegetables and whole grains. Avoid fried foods, high-fat dairy products, pastries and processed foods, as they may worsen anxiety.
  • Follow a regular sleep pattern. Do not take a nap during day time.
  • Avoid watching tv and using mobiles or laptops just before bedtime.
  • Avoid consumption of alcohol as it may increase drowsiness.

Special Advise

  • Do not use Midazom 0.5 Nasal Spray 50 mdi for more than 1 seizure cluster episode every three days and for more than five seizure cluster episodes per month. Please consult your doctor if you have concerns.

Disease/Condition Glossary

Seizure clusters: Seizure clusters are also known as acute repetitive seizures. These are instances of increased seizure activity, defined as two or more seizures occurring within a 24-hour period. They are stressful circumstances that can leave you feeling nervous, frustrated, or powerless. Stress, sickness with fever, sleep deprivation, missing prescriptions, and the use of alcohol or other non-medical substances are all potential causes of seizure clusters.

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Alcohol

Unsafe

Avoid consumption of alcohol with Midazom 0.5 Nasal Spray 50 mdi as it may increase drowsiness.

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Pregnancy

Caution

If you are pregnant or planning for pregnancy, inform your doctor before using Midazom 0.5 Nasal Spray 50 mdi. Babies born to mothers receiving Midazom 0.5 Nasal Spray 50 mdi late in pregnancy may be at risk of feeding or breathing problems, withdrawal symptoms or dangerously low body temperature.

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Breast Feeding

Caution

Midazom 0.5 Nasal Spray 50 mdi may be excreted in breast milk and may harm your baby. Therefore, discuss with your doctor the best way to feed your baby if you use Midazom 0.5 Nasal Spray 50 mdi.

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Driving

Caution

Avoid driving or operating machinery until you know how Midazom 0.5 Nasal Spray 50 mdi affects you.

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Liver

Consult your doctor

If you have liver problems, consult your doctor before using Midazom 0.5 Nasal Spray 50 mdi.

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Kidney

Consult your doctor

If you have kidney diseases/conditions, consult your doctor before using Midazom 0.5 Nasal Spray 50 mdi.

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Children

Unsafe

Midazom 0.5 Nasal Spray 50 mdi is not recommended for children below 12 years as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Ground Gloor, Shubham Apartment Near India Overseas Bank, Sardarnagar, Ahmedabad-382475, India
Other Info - MID0075

Author Details

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FAQs

Midazom 0.5 Nasal Spray 50 mdi is used to treat Seizure clusters (acute repetitive seizures).
Midazom 0.5 Nasal Spray 50 mdi contains Midazolam, which works by increasing the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby preventing fits by stabilizing the electrical activity of nerve cells in the brain.
If the seizure cluster continues after 10 minutes of the first dose, you can use the second dose of Midazom 0.5 Nasal Spray 50 mdi if advised by your doctor. However, the second dose should be given in the other nostril. Do not use more than two doses to treat a seizure cluster.
You are not recommended to take Midazom 0.5 Nasal Spray 50 mdi with opioids, alcohol or other central nervous system depressants as it may cause breathing problems, severe drowsiness or coma. Therefore, please consult your doctor before taking Midazom 0.5 Nasal Spray 50 mdi with any other medicines.
You are not recommended to stop using Midazom 0.5 Nasal Spray 50 mdi suddenly without consulting your doctor as it may cause withdrawal symptoms such as hallucinations, nervousness, shaking, muscle pain or cramps. Therefore, use Midazom 0.5 Nasal Spray 50 mdi for as long as your doctor has prescribed it, and if you experience any difficulty while using Midazom 0.5 Nasal Spray 50 mdi, please consult your doctor so that the dose may be reduced gradually.
Yes, Midazom 0.5 Nasal Spray 50 mdi may cause physical dependence if used for prolonged periods. Therefore, use Midazom 0.5 Nasal Spray 50 mdi only in the dose and for the duration as advised by your doctor.

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