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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Methnex G 300mg/500mcg Capsule is used to treat neuropathic pain. It contains Gabapentin and Methylcobalamin which rejuvenate and protect damaged nerve cells. In some cases, this medicine may cause side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Nexbon Lifesciences

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Methnex G 300mg/500mcg Capsule

Methnex G 300mg/500mcg Capsule belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Methnex G 300mg/500mcg Capsule consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Methnex G 300mg/500mcg Capsule helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Methnex G 300mg/500mcg Capsule may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Methnex G 300mg/500mcg Capsule. If you are a pregnant or breastfeeding mother, please consult your doctor before taking Methnex G 300mg/500mcg Capsule. Methnex G 300mg/500mcg Capsule causes drowsiness and dizziness, so drive only if you are alert. Methnex G 300mg/500mcg Capsule should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Methnex G 300mg/500mcg Capsule as it could lead to increased dizziness and sleepiness. 

Uses of Methnex G 300mg/500mcg Capsule

Treatment of Neuropathic pain and Epilepsy (fits).

Medicinal Benefits

Methnex G 300mg/500mcg Capsule is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

Directions for Use

Take Methnex G 300mg/500mcg Capsule with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Methnex G 300mg/500mcg Capsule

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

Drug Warnings

Inform your doctor before taking Methnex G 300mg/500mcg Capsule if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Methnex G 300mg/500mcg Capsule without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Methnex G 300mg/500mcg Capsule. Consult your doctor immediately if you experience suicidal tendencies. Keep Methnex G 300mg/500mcg Capsule away from direct sunlight. Do not store Methnex G 300mg/500mcg Capsule above 25ºC and keep it away from direct sunlight.

Drug Interactions

Drug-Drug Interaction: Methnex G 300mg/500mcg Capsule may interact with pain killers (hydrocodone, acetaminophen), antidepressants (duloxetine, escitalopram, sertraline), muscle relaxants (cyclobenzaprine), anti-anxiety drugs (alprazolam), fits medicines (pregabalin), antipsychotics (quetiapine), antibiotics (chloramphenicol), and anti-diabetics (metformin).

Drug-Food Interaction: Avoid alcohol consumption while taking Methnex G 300mg/500mcg Capsule as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Methnex G 300mg/500mcg Capsule may interact with disease conditions such as suicidal tendencies, renal dysfunction, and haemodialysis.

Drug-Drug Interactions Checker List

  • HYDROCODONE
  • ACETAMINOPHEN
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • CYCLOBENZAPRINE
  • ALPRAZOLAM
  • PREGABALIN
  • QUETIAPINE
  • CHLORAMPHENICOL
  • METFORMIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Special Advise

  • Close monitoring for suicidal thoughts/behaviour is required in people using Methnex G 300mg/500mcg Capsule. 

  • Using Methnex G 300mg/500mcg Capsule in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes, and hyperactivity. 

  • Let your doctor and the laboratory staff know if you are using Methnex G 300mg/500mcg Capsule since Gabapentin may interfere with laboratory tests. 

Disease/Condition Glossary

Epilepsy is the central nervous system's disorder in which brain activity becomes abnormal, leading to rapid fits/seizures episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy fits.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Methnex G 300mg/500mcg Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Methnex G 300mg/500mcg Capsule is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Methnex G 300mg/500mcg Capsule.

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Breast Feeding

Caution

Gabapentin in Methnex G 300mg/500mcg Capsule is excreted into breast milk. Please consult your doctor before taking Methnex G 300mg/500mcg Capsule if you are breastfeeding.

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Driving

Unsafe

Methnex G 300mg/500mcg Capsule causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Methnex G 300mg/500mcg Capsule. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Methnex G 300mg/500mcg Capsule. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Methnex G 300mg/500mcg Capsule is not recommended in children less than three years of age. The doctor will prescribe the dosage of Methnex G 300mg/500mcg Capsule based on the child's age and weight.

Manufacturer/Marketer address

Noor Pharmaceuticals- OM Rice Mill Colony, Near Gulab Nagar Chowk, Jagadhri, Yamuna Nagar, 135003, Haryana, India
Other Info - ME66764

Author Details

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FAQs

Methnex G 300mg/500mcg Capsule is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Methnex G 300mg/500mcg Capsule works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Methnex G 300mg/500mcg Capsule may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Methnex G 300mg/500mcg Capsule should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Methnex G 300mg/500mcg Capsule is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Methnex G 300mg/500mcg Capsule from the stomach. To avoid this, maintain a gap of two hours between Methnex G 300mg/500mcg Capsule and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Neuropathic pain is a chronic progressive nerve disease that occurs due to damaged sensory nerves. Neuropathic pain is stabbing, tingling, and sharp while muscle pain is dull and steady or crampy and spasmodic.
Inform your doctor before taking Methnex G 300mg/500mcg Capsule if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Pregnant and breastfeeding women should consult their doctor before taking Methnex G 300mg/500mcg Capsule.
Methnex G 300mg/500mcg Capsule is a combination medicine containing Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). It is used to treat neuropathic pain.
Peripheral neuropathy affects the nerves outside your brain or spinal cord. It causes tingling sensation, pain, numbness and burning sensation.
Do not discontinue Methnex G 300mg/500mcg Capsule without consulting your doctor. To treat your condition effectively, keep taking Methnex G 300mg/500mcg Capsule for the prescribed duration.
Methnex G 300mg/500mcg Capsule may cause sleepiness as a side effect. Do not drive or operate machinery unless you are alert.
No, do not take a higher than the recommended dose of Methnex G 300mg/500mcg Capsule as it might cause an overdose. Take Methnex G 300mg/500mcg Capsule in the dose and duration prescribed by the doctor.
Store Methnex G 300mg/500mcg Capsule at room temperature, in a dry place. Keep out of sight and reach of children.
Methnex G 300mg/500mcg Capsule may cause side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

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