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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 26, 2024 | 7:06 PM IST
Mecob12-G Tablet 10's is used to treat neuropathic pain. It contains Gabapentin and Methylcobalamin which rejuvenate and protect damaged nerve cells. In some cases, this medicine may cause side effects such as dizziness, sleepiness, tiredness, nausea and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Adduco Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Mecob12-G Tablet 10's

Mecob12-G Tablet 10's belongs to a class of 'anticonvulsants,' primarily used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia. Epilepsy is a neurological condition in which the brain's activity becomes abnormal with seizure episodes, sometimes losing awareness or consciousness. Neuralgia is a chronic pain condition of the nerves that occurs due to nerve damage or other neurological conditions like neuropathy, trigeminal neuralgia or shingles.

Mecob12-G Tablet 10's consists of two drugs: Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin treats seizures or fits by balancing chemical messengers (neurotransmitters) in the brain, further reducing their abnormal excitement in the brain. Methylcobalamin is a coenzyme form of vitamin B12. It rejuvenates and protects damaged nerve cells by producing a substance called myelin. It also regulates body functions, such as cell multiplication, blood formation, and protein synthesis. Together, Mecob12-G Tablet 10's helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Your doctor will decide the dosage and duration based on your medical condition. Sometimes, Mecob12-G Tablet 10's may have common side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

Let your doctor know if you are using any prescription, non-prescription drugs, and herbal products before starting Mecob12-G Tablet 10's. If you are a pregnant or breastfeeding mother, please consult your doctor before taking Mecob12-G Tablet 10's. Mecob12-G Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Mecob12-G Tablet 10's should not be given to children under three years old as safety and effectiveness have not been established. Avoid consuming alcohol along with Mecob12-G Tablet 10's as it could lead to increased dizziness and sleepiness. 

Uses of Mecob12-G Tablet 10's

Treatment of Neuropathic pain and Epilepsy (fits).

Medicinal Benefits

Mecob12-G Tablet 10's is used to treat post-herpetic neuralgia and epilepsy. It contains Gabapentin (anti-convulsant) and Methylcobalamin (Mecobalamin or vitamin B12). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain and lowers the risk of seizures. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. It is also used to treat alcoholic neuropathy and diabetic neuropathy (nerve damage due to high blood sugar levels).

Directions for Use

Take Mecob12-G Tablet 10's with or without food. Swallow it as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mecob12-G Tablet 10's

  • Dizziness

  • Sleepiness

  • Tiredness

  • Nausea 

  • Vomiting 

Drug Warnings

Inform your doctor before taking Mecob12-G Tablet 10's if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Consult your doctor if you are on haemodialysis and experience muscle pain or weakness, persistent stomach pain, nausea, and vomiting. Please do not stop taking Mecob12-G Tablet 10's without consulting your doctor as it could cause withdrawal symptoms. Pregnant and breastfeeding women should consult their doctor before taking Mecob12-G Tablet 10's. Consult your doctor immediately if you experience suicidal tendencies. Keep Mecob12-G Tablet 10's away from direct sunlight. Do not store Mecob12-G Tablet 10's above 25ºC and keep it away from direct sunlight.

Drug Interactions

Drug-Drug Interaction: Mecob12-G Tablet 10's may interact with pain killers (hydrocodone, acetaminophen), antidepressants (duloxetine, escitalopram, sertraline), muscle relaxants (cyclobenzaprine), anti-anxiety drugs (alprazolam), fits medicines (pregabalin), antipsychotics (quetiapine), antibiotics (chloramphenicol), and anti-diabetics (metformin).

Drug-Food Interaction: Avoid alcohol consumption while taking Mecob12-G Tablet 10's as it might cause increased dizziness and sleepiness.

Drug-Disease Interaction: Mecob12-G Tablet 10's may interact with disease conditions such as suicidal tendencies, renal dysfunction, and haemodialysis.

Drug-Drug Interactions Checker List

  • HYDROCODONE
  • ACETAMINOPHEN
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • CYCLOBENZAPRINE
  • ALPRAZOLAM
  • PREGABALIN
  • QUETIAPINE
  • CHLORAMPHENICOL
  • METFORMIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet as they can help in improving nerve health and preventing nerve pain.

  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.

  • Exercising regularly helps in improving overall health and combating pain. 

  • Rest well; get plenty of sleep.

  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreases numbness and pain.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Physical relaxation and massages can help provide symptomatic relief.

  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.

  • Acupuncture can be helpful by stimulating pressure points.

  • Using essential oils for massages can help increase circulation and boosts healing.

Special Advise

  • Close monitoring for suicidal thoughts/behaviour is required in people using Mecob12-G Tablet 10's. 

  • Using Mecob12-G Tablet 10's in children 3-12 years of age can cause emotional changes, aggressive behaviour, concentration problems, restlessness, school performance changes, and hyperactivity. 

  • Let your doctor and the laboratory staff know if you are using Mecob12-G Tablet 10's since Gabapentin may interfere with laboratory tests. 

Disease/Condition Glossary

Epilepsy is the central nervous system's disorder in which brain activity becomes abnormal, leading to rapid fits/seizures episodes with unusual behaviour and loss of awareness. Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy fits.

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mecob12-G Tablet 10's as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Mecob12-G Tablet 10's is not recommended during pregnancy unless prescribed by a doctor. Let your doctor know if you are pregnant or planning to conceive before taking Mecob12-G Tablet 10's.

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Breast Feeding

Caution

Gabapentin in Mecob12-G Tablet 10's is excreted into breast milk. Please consult your doctor before taking Mecob12-G Tablet 10's if you are breastfeeding.

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Driving

Unsafe

Mecob12-G Tablet 10's causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are mentally and physically alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Mecob12-G Tablet 10's. Dose adjustment may be needed in patients with liver impairment.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before taking Mecob12-G Tablet 10's. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Mecob12-G Tablet 10's is not recommended in children less than three years of age. The doctor will prescribe the dosage of Mecob12-G Tablet 10's based on the child's age and weight.

Country of origin

India

Manufacturer/Marketer address

517, First Floor, MKN Road, Alandur, Chennai - 600 016, Tamil Nadu, India.
Other Info - MEC0840

Author Details

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FAQs

Mecob12-G Tablet 10's is used to treat partial seizures (epilepsy) and various conditions of nerve pain/damage like post-herpetic neuralgia.
Mecob12-G Tablet 10's works by controlling the abnormal electrical activity of the brain that causes seizures (fits). It also helps in the rejuvenation and protection of damaged nerve cells.
Mecob12-G Tablet 10's may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a balanced diet.
People taking Mecob12-G Tablet 10's should be closely monitored for suicidal thoughts or behaviour. Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.
If Mecob12-G Tablet 10's is taken along with antacid medicines containing aluminium and magnesium, it may lower the absorption of Mecob12-G Tablet 10's from the stomach. To avoid this, maintain a gap of two hours between Mecob12-G Tablet 10's and antacid medicines.
If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.
Neuropathic pain is a chronic progressive nerve disease that occurs due to damaged sensory nerves. Neuropathic pain is stabbing, tingling, and sharp while muscle pain is dull and steady or crampy and spasmodic.
Inform your doctor before taking Mecob12-G Tablet 10's if you have a medical history of heart problems, bipolar syndrome, and nervous system disorders. Pregnant and breastfeeding women should consult their doctor before taking Mecob12-G Tablet 10's.
Mecob12-G Tablet 10's is a combination medicine containing Gabapentin (anticonvulsant) and Methylcobalamin (Mecobalamin or vitamin B12). It is used to treat neuropathic pain.
Peripheral neuropathy affects the nerves outside your brain or spinal cord. It causes tingling sensation, pain, numbness and burning sensation.
Do not discontinue Mecob12-G Tablet 10's without consulting your doctor. To treat your condition effectively, keep taking Mecob12-G Tablet 10's for the prescribed duration.
Mecob12-G Tablet 10's may cause sleepiness as a side effect. Do not drive or operate machinery unless you are alert.
No, do not take a higher than the recommended dose of Mecob12-G Tablet 10's as it might cause an overdose. Take Mecob12-G Tablet 10's in the dose and duration prescribed by the doctor.
Store Mecob12-G Tablet 10's at room temperature, in a dry place. Keep out of sight and reach of children.
Mecob12-G Tablet 10's may cause side effects like dizziness, sleepiness, tiredness, nausea and vomiting. These side effects do not require medical attention and gradually resolve over time. However, you are advised to talk to your doctor if you experience these side effects for a longer duration.

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