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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 22, 2024 | 7:37 PM IST
Mantaglial-10 Tablet 10's is used to treat moderate to severe Alzheimer's disease. It contains Memantine, which decreases the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease. In some cases, it may cause common side effects, such as headache, sleepiness, dizziness, diarrhoea, constipation, balance disorders, and high blood pressure. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Prescription drug

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Composition

MEMANTINE-10MG

Manufacturer/Marketer

Glial Life Science Llp

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Mantaglial-10 Tablet 10's

Mantaglial-10 Tablet 10's belongs to a group of medicines called anti-dementia agents used to treat moderate to severe Alzheimer's disease. Alzheimer's disease is a neurological disorder that causes dementia (memory loss) and slowly destroys the ability to think, learn, communicate, and handle daily activities.

Mantaglial-10 Tablet 10's contains 'Memantine', which is an NMDA receptor antagonist. It acts on the N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals that play an essential role in memory. Mantaglial-10 Tablet 10's decreases the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease.

Take Mantaglial-10 Tablet 10's with or without food. You are advised to take Mantaglial-10 Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, sleepiness, dizziness, diarrhoea, constipation, balance disorders, and high blood pressure. You are advised to talk to your doctor if you experience any of these side effects persistently.

Please do not stop taking Mantaglial-10 Tablet 10's without consulting your doctor. Consult your doctor before taking Mantaglial-10 Tablet 10's if you are pregnant or breastfeeding. Avoid driving or operating machinery as Mantaglial-10 Tablet 10's causes dizziness and sleepiness and may affect reactivity. Avoid consuming alcohol along with Mantaglial-10 Tablet 10's as it could lead to increased dizziness. Mantaglial-10 Tablet 10's is not recommended for children below 18 years as the safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Mantaglial-10 Tablet 10's

Treatment of Alzheimer's disease

Medicinal Benefits

Mantaglial-10 Tablet 10's belongs to a group of anti-dementia agents called NMDA receptor antagonists. Mantaglial-10 Tablet 10's is used to treat moderate to severe dementia (memory loss) of Alzheimer's disease. Mantaglial-10 Tablet 10's acts on the N-methyl-D-aspartate (NMDA) receptors involved in transmitting nerve signals, which play an important role in memory. Mantaglial-10 Tablet 10's works by decreasing the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease.

Directions for Use

Swallow the medicine as a whole with a glass of water; do not chew or crush the tablet/capsule.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Mantaglial-10 Tablet 10's

  • Headache
  • Sleepiness
  • Dizziness
  • Confusion
  • Diarrhea
  • Constipation
  • Balance disorders
  • High blood pressure
  • Shortness of breath
  • Elevated liver function tests

Drug Warnings

Do not take Mantaglial-10 Tablet 10's if you are allergic to any of its contents. Inform your doctor if you have/had epilepsy (fits), heart attack, congestive heart failure, or uncontrolled high blood pressure. Talk to your doctor if you change your diet from normal to strict vegetarian or if you are having any kidney problems or urinary tract infections. Avoid taking amantadine (used to treat Parkinson's disease), ketamine (anesthetic), dextromethorphan (used to treat cough), and other NMDA-antagonists at the same time. Consult your doctor before taking Mantaglial-10 Tablet 10's if you are pregnant or breastfeeding. Avoid driving or operating machinery as Mantaglial-10 Tablet 10's causes dizziness, sleepiness, and may affect reactivity. Avoid consuming alcohol along with Mantaglial-10 Tablet 10's as it could lead to increased dizziness. Mantaglial-10 Tablet 10's is not recommended for children below 18years as the safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Mantaglial-10 Tablet 10's may have interaction with antiparkinson's (amantadine), anaesthetic (ketamine), anti-tussive (dextromethorphan), skeletal muscle relaxant (dantrolene, baclofen), antacid (cimetidine, ranitidine), anti-arrhythmic (procainamide, quinidine), anti-malarial (quinine), an alkaloid (nicotine), diuretic (hydrochlorothiazide), dopaminergic agonist (levodopa, bromocriptine), anti-psychotic (quetiapine), anticonvulsants (used to treat fits), barbiturates (used to induce sleep), neuroleptics (used to treat mental disorders), and oral anticoagulants.

Drug-Food Interactions: Avoid alcohol consumption while taking Mantaglial-10 Tablet 10's as it might cause increased dizziness and sleepiness. Avoid smoking as nicotine might interact with the working of Mantaglial-10 Tablet 10's.

Drug-Disease Interactions: Inform your doctor if you have high blood pressure, liver or kidney impairment.

Drug-Drug Interactions Checker List

  • AMANTADINE
  • DEXTROMETHORPHAN
  • BACLOFEN
  • CIMETIDINE
  • RANITIDINE
  • PROCAINAMIDE
  • QUINIDINE
  • QUININE
  • NICOTINE
  • HYDROCHLOROTHIAZIDE
  • LEVODOPA
  • BROMOCRIPTINE
  • QUETIAPINE
  • DANTROLENE
  • KETAMINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practicing meditation or yoga.
  • Include fruits and vegetables in your diet as they contain anti-oxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt, and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Special Advise

  • Regularly monitor blood pressure levels while taking Mantaglial-10 Tablet 10's as it may cause high blood pressure.

Disease/Condition Glossary

Alzheimer's disease: Alzheimer's disease is a neurological disorder that causes dementia (memory loss) and slowly destroys the ability to think, learn, communicate, and, eventually, the ability to handle daily activities. It is the most common cause of dementia (memory loss) in adults. Dementia is the loss of cognitive functioning, such as remembering, thinking, and reasoning. The causes of this disease are abnormal functioning of brain cells, which cause a disturbance in communication between them. The risk factors are age, family history, and genetics of a person. Alzheimer's disease symptoms include memory loss, trouble with familiar tasks, difficulties with problem-solving, trouble with writing or talking, disorientation, problems with reasoning or judgment, and mood and personality changes. In most people, the symptoms of Alzheimer's appear in their mid-60s.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mantaglial-10 Tablet 10's as it may cause increased dizziness.

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Pregnancy

Caution

Mantaglial-10 Tablet 10's belongs to pregnancy category B. Caution should be exercised; it is advisable to consult a doctor before using Mantaglial-10 Tablet 10's.

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Breast Feeding

Caution

It is not recommended to breastfeed while taking Mantaglial-10 Tablet 10's. Consult your doctor before taking Mantaglial-10 Tablet 10's if you are breastfeeding.

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Driving

Unsafe

Mantaglial-10 Tablet 10's causes dizziness, sleepiness and might change your reactivity. Do not drive or operate machinery.

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Liver

Caution

Mantaglial-10 Tablet 10's should be used with caution in patients with severe hepatic impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with severe kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Mantaglial-10 Tablet 10's is not recommended for children below 18years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

7, Kishan Park 2, Ctm Cross Rd, Near Kailash Colony, Near Purvadip Society, Amraiwadi, Ahmedabad, Gujarat 380026
Other Info - MAN0523

Author Details

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FAQs

Mantaglial-10 Tablet 10's is used to treat moderate to severe Alzheimer's disease, a neurological disorder that causes dementia (memory loss) and slowly destroys the ability to think, learn, communicate, and handle daily activities.
Mantaglial-10 Tablet 10's acts on the N-methyl-D-aspartate (NMDA) receptors involved in the transmission of nerve signals which play an important role in learning and memory. Mantaglial-10 Tablet 10's decreases the brain's abnormal activity and may improve the ability to think and remember or might slow the loss of these abilities in people with Alzheimer's disease.
Mantaglial-10 Tablet 10's is used to treat dementia associated with Alzheimer's disease. Dementia (memory loss) is the loss of cognitive functioning, such as remembering, thinking, and reasoning.
Mantaglial-10 Tablet 10's does not cure Alzheimer's disease. Mantaglial-10 Tablet 10's improves the ability to think and remember or slow the loss of these abilities in people with Alzheimer's disease. Research is still in progress for the cure of Alzheimer's disease.
Do not discontinue Mantaglial-10 Tablet 10's without consulting your doctor. To treat your condition effectually continue taking Mantaglial-10 Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Mantaglial-10 Tablet 10's.
Diarrhoea could be a side-effect of Mantaglial-10 Tablet 10's. Drink plenty of fluids and eat fibre rich food if you experience diarrhoea. Consult your doctor if you experience excessive diarrhoea or if you find blood in stools.
Mantaglial-10 Tablet 10's may cause high blood pressure. Regular monitoring of blood pressure levels is advised while taking Mantaglial-10 Tablet 10's. Consult your doctor if you experience any fluctuations.
Mantaglial-10 Tablet 10's does not have the potential for abuse. It is not a habit-forming drug.
Take Mantaglial-10 Tablet 10's as advised by the doctor. To help you remember to take Mantaglial-10 Tablet 10's, take it at around the same time daily. Mantaglial-10 Tablet 10's should be swallowed as a whole with water; do not crush or chew it.
Mantaglial-10 Tablet 10's starts working in 3-8 hours. However, it can take up to 3 months to notice full benefits.
The signs and symptoms of overdose include confusion, agitation, weakness, visual hallucinations, vertigo, coma, slowed movement, excess sleepiness, dizziness, lethargy (lack of energy), loss of consciousness, increased blood pressure, ECG changes, slow heart rate, psychosis, restlessness, stupor, unsteady gait (unstable pattern of walking), and vomiting. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.
Mantaglial-10 Tablet 10's decreases the brain's abnormal activity and may improve the ability to think and remember.
Dementia is the loss of cognitive functioning, such as remembering, thinking, and reasoning. The causes of this disease are abnormal functioning of brain cells, which leads to a disturbance in communication between them.
Do not discontinue Mantaglial-10 Tablet 10's without consulting your doctor. To treat your condition effectively, keep taking Mantaglial-10 Tablet 10's for the prescribed duration.
Mantaglial-10 Tablet 10's causes sleepiness as a side effect. Therefore, avoid driving or operating machinery.
Mantaglial-10 Tablet 10's can be combined with donepezil if prescribed by the doctor.
Consult the doctor if you are taking antiparkinson's (amantadine), anaesthetic (ketamine), anti-tussive (dextromethorphan), skeletal muscle relaxant (dantrolene, baclofen), antacid (cimetidine, ranitidine), anti-arrhythmic (procainamide, quinidine), anti-malarial (quinine), an alkaloid (nicotine), diuretic (hydrochlorothiazide), dopaminergic agonist (levodopa, bromocriptine), anti-psychotic (quetiapine), anticonvulsants (used to treat fits), barbiturates (used to induce sleep), neuroleptics (used to treat mental disorders), and oral anticoagulants.
Mantaglial-10 Tablet 10's may have interaction with cardiac medicines like anti-arrhythmic (procainamide, quinidine), and diuretic (hydrochlorothiazide). Consult the doctor before taking these medicines with Mantaglial-10 Tablet 10's.
Mantaglial-10 Tablet 10's can be taken with or without food.
Mantaglial-10 Tablet 10's may cause common side effects such as headache, sleepiness, dizziness, diarrhoea, constipation, balance disorders, and high blood pressure. You are advised to talk to your doctor if you experience any of these side effects persistently.
Pregnant women should take Mantaglial-10 Tablet 10's only if prescribed by the doctor. It is advisable to consult a doctor before using Mantaglial-10 Tablet 10's if you are pregnant, think you may be pregnant or planning for pregnancy.
Breastfeeding is not recommended while taking Mantaglial-10 Tablet 10's. Consult your doctor before taking Mantaglial-10 Tablet 10's if you are breastfeeding.
Mantaglial-10 Tablet 10's should be used with caution in patients with kidney or liver disease and only if prescribed by the doctor. Please consult the doctor if you have liver or kidney problems.

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